Investigation of smell and taste function in patients with obstructive sleep apnoea syndrome

2019 ◽  
Vol 133 (05) ◽  
pp. 376-379 ◽  
Author(s):  
A Yenigun ◽  
N Degirmenci ◽  
S S Goktas ◽  
R Dogan ◽  
O Ozturan

AbstractObjectiveThis study investigated the relationship between disease severity and taste and smell functions in patients with obstructive sleep apnoea syndrome.MethodsA total of 65 patients with recurrent upper airway obstruction during sleep were included. Participants were divided into four groups according to apnoea-hypopnoea index, obtained on polysomnography. Smell and taste tests were performed on these patients.ResultsA significant difference was observed between the smell thresholds of the groups for the identification test (p = 0.016). In the taste test, significant differences were observed between the groups in terms of sweet, sour, salty and bitter taste test thresholds (p = 0.029, p = 0.0005, p = 0.001 and p = 0.017, respectively).ConclusionAs sleep apnoea severity increased (according to the apnoea-hypopnoea index) in obstructive sleep apnoea syndrome patients, the taste and smell thresholds decreased due to the effect of neuropathy and inflammation in the upper respiratory tract.

Author(s):  
S. P. Rubnikovich ◽  
I. S. Abelskaya ◽  
Yu. L. Denisova ◽  
S. V. Sirak ◽  
V. G. Shishov

The goal of the study was to analyze the upper respiratory tract condition indicators obtained by means of сone beam computed tomography (CBCT) for patients with dentition system diseases and obstructive sleep apnoea syndrome. Patients were divided into 3 study groups. The control group (the 1st study group) included the CBCT data obtained for 33 healthy patients. The 2nd study group included the CBCT data obtained for 136 patients with dentition system diseases (partial secondary edentia combined with chronic generalized periodontitis) without sleep disorder signs. The 3rd study group included the CBCT data obtained for 70 patients with partial secondary edentia combined with deep distal occlusion and obstructive sleep apnoea syndrome (OSAS). The CBCT method using the proposed diagnosis criteria made it possible to identify not only dentition system diseases, but also the dysfunction of the upper respiratory tract, in particular the OSAS causes. It was found with confidence that the reduction of the upper respiratory tract diagnostic indicators by 40 % or more, as compared to the regulatory indicators of healthy patients, led to the dysfunction of the respiratory tract and the apnoea development. Deep distal occlusion and secondary edentia conditioned the presence of the upper respiratory tract concave configuration and the localization of the minimum cross-sectional area below the occlusion plane, which increases the probability of development and progression of the obstructive sleep apnoea syndrome.


2019 ◽  
Vol 19 (4) ◽  
pp. 310
Author(s):  
Redha Al Lawati ◽  
Mohammed A. Al Abri ◽  
Balaji Kuppuswamy ◽  
Amira Al-Kharousi ◽  
Al Yaqdhan Al-Atbi ◽  
...  

Objectives: Obstructive sleep apnoea syndrome (OSAS) is a growing health concern as it is associated with serious comorbidities. OSAS is mainly related to obesity, age, gender and a narrowed upper airway is commonly seen in patients with OSAS. This study aimed to compare spirometry parameters between obese OSAS patients and non-obese OSAS patients when patients moved from sitting to supine. Methods: This cross-sectional study was conducted at Sultan Qaboos University Hospital, Muscat, Oman, between December 2009 and December 2010. Patients with severe OSAS and who were OSAS treatment naïve were recruited. Spirometry was performed in all patients in sitting and supine positions to assess forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), FEV1/FVC, forced expiratory flow (FEF) 50%, FEF 25–75%, maximum forced inspiratory flow and expiratory reserve volume. The mean difference in spirometry parameters between patients in sitting and supine positions was calculated. Results: A total of 27 OSAS patients (19 males and 8 females) were included in this study. There was a significant difference in FEV1/FVC in obese and non-obese patients when changing position (P = 0.03). In addition, there was a significant change between male and female patients’ FVC percentages (P <0.05). Male patients with OSAS had reduced FVC compared to females. There was no significant difference in the remaining spirometry parameters with patients’ change of position. Conclusion: A supine position may cause lower airway obstruction in obese patients with OSAS. The reduced FVC in males possibly contributes to the high prevalence of OSAS in men compared to women.Keywords: Obstructive Sleep Apnea; Obesity; Gender; Spirometry; Posture; Oman.


Sign in / Sign up

Export Citation Format

Share Document