The texts of the Dead Sea Scrolls are great importance for the reconstruction of the theological and ideological factors of the authors of the New Testament and can shed light on the understanding of some difficult passages of the New Testament. It is well known that the text of 1 Thessalonians 4:4 became Crux Interpretum for its researchers. Since the period of the Church Fathers, the text has had three conflicting interpretations. Modern research has continued this trend. The discovery in the 40s of the XX century Dead Sea Scrolls, gave a new look at some problematic texts of the New Testament. Thus, the two texts 4QSamb and 4Q416 2 ii 21 shed light on the discussion of 1 Thessalonians 4:4. But a closer examination revealed that their interpretation was also ambiguous, which in turn gave rise to a new wave of discussion. So, three options for understanding the texts were proposed. Consensus has not yet been reached. The text of 4QSamb was studied by F. Cross, D. Freedman, P. Andersen. Text 4Q416 2 ii 21 has been the subject of many publications, among the most important are the following: J. Stragnell, D. Harrington, T. Elgwin, J. Smith, M. Kister, B. Wald, F. Martinez. The purpose of the study is to critically analyze the interpretations of two texts from the corpus of Dead Sea Scrolls, 4QSamb and 4Q416 2 ii 21. The article examines two important texts from the Dead Sea Scrolls, 4QSamb and 4Q416 2 ii 21, which shed light on a possible interpretation of a passage from Paul's corpus, 1 Thessalonians 4: 4. The 4QSamb study by scientists led to two interpretations of this passage. The article shows that understanding 4QSamb has a sexual context, and can locally indicate the male genitalia. The study of the text 4Q416 2 ii 21 led to the emergence of three radically different interpretations. Although each approach is well-argued and has its advantages, the paper has shown that the interpretation proposed by Elgwin Thorleif is more true in view of paleographic research, lexical analysis, and the immediate context of the passage. The article showed that the word כלי in the texts is used as a euphemism in the meaning of the male genitalia. This conclusion provides an important context for understanding 1 Thessalonians 4:4, that the interpretation of the word σκεῦός in this text must take into account the possibility of its interpretation in the sense of male "genitals".