An area specifically devoted to tool use in human left inferior parietal lobule

AbstractA comparative fMRI study by Peeters et al. (2009) provided evidence that a specific sector of left inferior parietal lobule is devoted to tool use in humans, but not in monkeys. We propose that this area represents the neural substrate of the human capacity to understand tool use by using causal reasoning.

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A brain network that supports consensus-seeking and conflict-resolving of college couples’ shopping interaction

Scientific Reports ◽

10.1038/s41598-020-74699-1 ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

HanShin Jo ◽

Chiu-Yueh Chen ◽

Der-Yow Chen ◽

Ming-Hung Weng ◽

Chun-Chia Kung

Keyword(s):

Brain Network ◽

The Other ◽

Inferior Parietal Lobule ◽

Social Decision ◽

Decision Network ◽

Fmri Study ◽

The Social ◽

Neural Substrate ◽

Preference Ratings ◽

Parietal Lobule

Abstract One of the typical campus scenes is the social interaction between college couples, and the lesson couples must keep learning is to adapt to each other. This fMRI study investigated the shopping interactions of 30 college couples, one lying inside and the other outside the scanner, beholding the same item from two connected PCs, making preference ratings and subsequent buy/not-buy decisions. The behavioral results showed the clear modulation of significant others’ preferences onto one’s own decisions, and the contrast of the “shop-together vs. shop-alone”, and the “congruent (both liked or disliked the item, 68%) vs. incongruent (one liked but the other disliked, and vice versa)” together trials, both revealed bilateral temporal parietal junction (TPJ) among other reward-related regions, likely reflecting mentalizing during preference harmony. Moreover, when contrasting “own-high/other-low vs. own-low/other-high” incongruent trials, left anterior inferior parietal lobule (l-aIPL) was parametrically mapped, and the “yield (e.g., own-high/not-buy) vs. insist (e.g., own-low/not-buy)” modulation further revealed left lateral-IPL (l-lIPL), together with left TPJ forming a local social decision network that was further constrained by the mediation analysis among left TPJ–lIPL–aIPL. In sum, these results exemplify, via the two-person fMRI, the neural substrate of shopping interactions between couples.

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Consensus-seeking and conflict-resolving ---an fMRI study on college couples’ shopping interaction

10.1101/2020.03.11.986786 ◽

2020 ◽

Author(s):

HanShin Jo ◽

Chiu-Yueh Chen ◽

Der-Yow Chen ◽

Ming-Hung Weng ◽

Chun-Chia Kung

Keyword(s):

Social Interaction ◽

The Other ◽

Inferior Parietal Lobule ◽

Social Decision ◽

Decision Network ◽

Fmri Study ◽

The Social ◽

Neural Substrate ◽

Preference Ratings ◽

Parietal Lobule

AbstractOne of the typical campus scenes is the social interaction between college couples, and the lesson couples must keep learning is to adapt to each other. This fMRI study investigated the shopping interactions of 30 college couples, one lying inside and the other outside the scanner, beholding the same item from two connected PCs, making preference ratings and subsequent buy/not-buy decisions. The behavioral results showed the clear modulation of significant others’ preferences onto one’s own decisions, and the contrast of the “shop-together vs. shop-alone”, and the “congruent (both liked or disliked the item, 68%) vs. incongruent (one liked but the other disliked, and vice versa)” together trials, both revealed bilateral temporal parietal junction (TPJ) among other reward-related regions, likely reflecting mentalizing during preference harmony. Moreover, when contrasting “own-high/other-low vs. own-low/other-high” incongruent trials, left anterior inferior parietal lobule (l-aIPL) was parametrically mapped, and the “yield (e.g., own-high/not-buy) vs. insist (e.g., own-low/not-buy)” modulation further revealed left lateral-IPL (l-lIPL), together with left TPJ forming a local social decision network that was further constrained by the mediation analysis among left TPJ-lIPL-aIPL. In sum, these results exemplify, via the two-person fMRI, the neural substrate of shopping interactions between couples.

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Diminished activation of the right Inferior Parietal Lobule as a neural substrate of impaired cartoon-jokes comprehension in schizophrenia outpatients

Schizophrenia Research ◽

10.1016/j.schres.2018.01.004 ◽

2018 ◽

Vol 197 ◽

pp. 593-595 ◽

Cited By ~ 3

Author(s):

Przemysław Adamczyk ◽

Miroslaw Wyczesany ◽

Aleksandra Domagalik ◽

Kamil Cepuch ◽

Artur Daren ◽

...

Keyword(s):

Inferior Parietal Lobule ◽

Neural Substrate ◽

Parietal Lobule ◽

The Right

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Structural Disconnection of the Tool Use Network after Left Hemisphere Stroke Predicts Limb Apraxia Severity

Cerebral Cortex Communications ◽

10.1093/texcom/tgaa035 ◽

2020 ◽

Vol 1 (1) ◽

Author(s):

Frank E Garcea ◽

Clint Greene ◽

Scott T Grafton ◽

Laurel J Buxbaum

Keyword(s):

Left Hemisphere ◽

Temporal Lobe ◽

Tool Use ◽

Critical Issue ◽

Inferior Parietal Lobule ◽

Sensory Motor ◽

Limb Apraxia ◽

Parietal Lobule ◽

Skilled Action ◽

Left Hemisphere Stroke

Abstract Producing a tool use gesture is a complex process drawing upon the integration of stored knowledge of tools and their associated actions with sensory–motor mechanisms supporting the planning and control of hand and arm actions. Understanding how sensory–motor systems in parietal cortex interface with semantic representations of actions and objects in the temporal lobe remains a critical issue and is hypothesized to be a key determinant of the severity of limb apraxia, a deficit in producing skilled action after left hemisphere stroke. We used voxel-based and connectome-based lesion-symptom mapping with data from 57 left hemisphere stroke participants to assess the lesion sites and structural disconnection patterns associated with poor tool use gesturing. We found that structural disconnection among the left inferior parietal lobule, lateral and ventral temporal cortices, and middle and superior frontal gyri predicted the severity of tool use gesturing performance. Control analyses demonstrated that reductions in right-hand grip strength were associated with motor system disconnection, largely bypassing regions supporting tool use gesturing. Our findings provide evidence that limb apraxia may arise, in part, from a disconnection between conceptual representations in the temporal lobe and mechanisms enabling skilled action production in the inferior parietal lobule.

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