Steroid-Induced Mania: A Case Report

2012 ◽  
Vol 29 (3) ◽  
pp. 194-195 ◽  
Author(s):  
Carol Cassidy ◽  
Shobhna Sahay ◽  
Fiona McNicholas
Keyword(s):  
Case Report ◽  
Side Effects ◽  
Children And Adolescents ◽  
Lymphocytic Leukaemia ◽  
Early Recognition ◽  
Age Group ◽  
Medical Conditions ◽  
Acute Lymphocytic Leukaemia ◽  
Psychiatric Complications ◽  
Psychiatric Side Effects

AbstractCorticosteroids are commonly used in the treatment of a variety of medical conditions in children and adolescents. However, adverse psychiatric side effects can occur which pose challenges in treatment of medical conditions. This case highlights some of these challenges, in particular the treatment of steroid-induced psychiatric complications in Acute Lymphocytic Leukaemia (ALL). It also accentuates the importance of awareness among pediatricians of the potential adverse psychiatric effects when prescribing corticosteroids in this age group. Families need to be advised accordingly to ensure early recognition and treatment.

scholarly journals Antibiomania: a case report of clarithromycin and amoxicillin-clavulanic acid induced manic episodes separately

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Edith Paula Meszaros ◽  
Catheline Stancu ◽  
Alessandra Costanza ◽  
Marie Besson ◽  
François Sarasin ◽  
...  
Keyword(s):  
Case Report ◽  
Clavulanic Acid ◽  
Psychiatric Symptoms ◽  
Early Recognition ◽  
Manic Episode ◽  
Psychiatric Symptomatology ◽  
Acid Therapy ◽  
Clinical Reminder ◽  
Amoxicillin Clavulanic Acid ◽  
Psychiatric Side Effects

Abstract Background Antibiomania is a rare but recognized side effect with yet unclear definite pathogenesis although multiple hypotheses have been proposed. The novelty of this case is the suspected pharmacodynamic drug-drug interaction between clarithromycin and amoxicillin-clavulanic acid. Case presentation We present the occurrence of a brief manic episode concerning a 50-year-old man with no psychiatric history, first started on amoxicillin-clavulanic acid therapy and then switched to clarithromycin for left basal pneumonia. Shortly after the antibiotic prescription, he presented psychiatric symptomatology (logorrhea, elevated mood, irritability, increase in physical activity and delusions). The antibiotic was stopped and the patient received lorazepam (2.5 mg p.o.) to treat psychomotor agitation. Approximately 12 h after clarithromycin cessation, amelioration was already observed, supporting the diagnosis of a clarithromycin-induced manic episode. Amoxicillin-clavulanic acid was then reintroduced because of the pneumonia and psychiatric symptoms reemerged. This second antibiotic was also stopped, and 1 week later, the patient was symptom-free. Conclusion The emergence of psychiatric side effects related to antibiotherapy, which is a common treatment, can greatly impact a patient’s quality of life. Early recognition and intervention could substantially influence the administered medical care and recovery. Moreover, given the widespread use of antibiotics including in combination, we thought our case report might be clinically useful as a clinical reminder relevant to the use of antibiotic combinations.

scholarly journals Ethambutol toxic optic neuropathy: A case report and review

2018 ◽  
Vol 77 (1) ◽  
Author(s):  
Kevin C. Phillips ◽  
Peter C. Clarke-Farr
Keyword(s):  
Case Report ◽  
Side Effects ◽  
Optic Neuropathy ◽  
Vision Loss ◽  
Early Recognition ◽  
Treatment Cessation ◽  
Toxic Optic Neuropathy ◽  
Vision Restoration

This article presents a case of ethambutol toxic optic neuropathy determined during the routine optometric examination of a 66-year-old man. Ethambutol is an established drug for the treatment of tuberculosis, but has significant side effects, notably optic neuropathy. The prognosis for vision restoration is unpredictable, with the possibility of permanent vision loss. Treatment cessation is the only option to limit ocular damage; therefore, the early recognition of ethambutol optic neuropathy by optometrists is essential.

Induced psychosis after withdrawal of varenicline: a case report

2011 ◽  
Vol 23 (5) ◽  
pp. 252-255
Author(s):  
María T. López Arteaga ◽  
Carlos Amo ◽  
Eva M. Sánchez Morla ◽  
Marina Sánchez Román
Keyword(s):  
Case Report ◽  
Side Effects ◽  
Single Case ◽  
Psychotic Symptoms ◽  
Psychiatric History ◽  
Single Case Report ◽  
Withdrawal Of Treatment ◽  
Discontinuation Of Treatment ◽  
Poor Tolerance ◽  
Psychiatric Side Effects

López Arteaga MT, Amo C, Sánchez Morla EM, Sánchez Román M. Induced psychosis after withdrawal of varenicline: a case report.Objective: Varenicline has been associated with psychiatric side effects, and cases with psychotic symptoms during treatment have been reported, few of them after the withdrawal. We describe a case with no current or previous medical or psychiatric history.Method: A single case report.Results: The patient without previous psychiatric pathology, following the withdrawal of treatment with varenicline, experiences delirium and behavioural disturbances. There was a remission of symptoms after 3 weeks of treatment with risperidone.Conclusion: Discontinuation of treatment with varenicline due to poor tolerance for side effects (nausea and insomnia) could trigger psychotic symptoms in subjects with no personal or family psychiatric history.

scholarly journals How safe is soy in infancy? Case report of thelarche in an infant

2021 ◽  
Vol 9 (1) ◽  
pp. 129
Author(s):  
Parijat R. Tripathi ◽  
Rahul Reddy
Keyword(s):  
Case Report ◽  
Side Effects ◽  
Soy Protein ◽  
Milk Protein ◽  
Lactose Intolerance ◽  
Infant Nutrition ◽  
Clinical Indication ◽  
Age Group ◽  
Estradiol Levels

Soy protein based formulas are commonly used in infant nutrition for various indications like lactose intolerance and cow’s milk protein allergy. There are concerns regarding phytoestrogen related and other side effects of these formulas. We are describing a case of possible soy formula induced thelarche in a 7 months infant. There was normalization of estradiol levels with some clinical improvement after stopping soy formula over a follow-up of 12 months duration. We suggest further studies to evaluate hormone levels in infants on soy formulas and to consider it only for appropriate clinical indication and age group.

scholarly journals Mefloquine Long Half-Life is Associated with Sustained Psychiatric Side Effects: A Case Report

2018 ◽  
Vol 02 (01) ◽  
Author(s):  
Eric Constant ◽  
Emmanuel Hermans ◽  
Pierre Wallemacq ◽  
Arnaud Capron
Keyword(s):  
Case Report ◽  
Side Effects ◽  
Half Life ◽  
Psychiatric Side Effects

Combination Chemotherapy for Marrow Relapse in Children and Adolescents with Acute Lymphocytic Leukaemia

2009 ◽  
Vol 26 (4) ◽  
pp. 292-296 ◽  
Author(s):  
Sergio Amadori ◽  
Maria Antonietta ◽  
Aloe Spiriti ◽  
Giovanna Meloni ◽  
Leonardo Pacilli ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Combination Chemotherapy ◽  
Lymphocytic Leukaemia ◽  
Acute Lymphocytic Leukaemia

scholarly journals A Case Report on Scalp edema in a case of HSP in a young adult

2019 ◽  
Vol 8 (2) ◽  
pp. 35-37 ◽  
Author(s):  
S. Thapaliya ◽  
M. Nepal ◽  
B. Nepal ◽  
R. Pathak
Keyword(s):  
Case Report ◽  
Young Adult ◽  
Early Recognition ◽  
Renal Involvement ◽  
Organ Damage ◽  
Small Vessel ◽  
Small Vessel Vasculitis ◽  
Age Group ◽  
Palpable Purpura ◽  
Schonlein Purpura

Henoch Schonlein Purpura (HSP) is a systemic small vessel vasculitis which most commonly affects children. HSP is characterized by non-thrombocytopenic palpable purpura, arthritis or arthalgia, gastrointestinal and renal involvement. Scalp edema is uncommon in children over 3 years. Early recognition, especially outside of the typical age group, with appropriate management can reduce morbidity and organ damage. We present a case of a young adult with HSP who

Psychiatric side effects of interferon-β in multiple sclerosis

2006 ◽  
Vol 21 (3) ◽  
pp. 186-193 ◽  
Author(s):  
J.-L. Goeb ◽  
C. Even ◽  
G. Nicolas ◽  
B. Gohier ◽  
F. Dubas ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Side Effects ◽  
Depressive Disorders ◽  
Antidepressant Treatment ◽  
Treatment Programs ◽  
Psychiatric Status ◽  
History Of ◽  
Major Depressive Disorders ◽  
Psychiatric Complications ◽  
Psychiatric Side Effects

AbstractPsychiatric disorders, especially depression, are frequent in patients with multiple sclerosis (MS). They are attributed both to the psychosocial impact of a chronic, usually progressive, disabling illness and to cerebral demyelination. Besides, drugs such as corticosteroids and possibly interferon (IFN) may also have depressogenic effects. Major depressive disorders and/or suicidal ideation are a major concern and efforts to identify and minimize these reactions are of much importance. Psychiatric side effects, particularly depression, are widely reported with IFN-α and have been suspected with IFN-β but are not yet fully established. Our review of the literature revealed that most studies discard an association between IFN-β and depression or suicide. However, few patients, especially those with a history of depression, might be at higher risk for depression when treated with IFN-β. Overall, considering the uncertainty of a link between IFN-β and depression and/or suicide, as well as the complete remission of psychiatric complications after IFN discontinuation and/or antidepressant treatment, physicians should closely monitor the psychiatric status of patients, but should not refrain from including them in IFN-β treatment programs, even when they have past or present depression.

Steroids, psychosis and poly-substance abuse

2014 ◽  
Vol 32 (2) ◽  
pp. 227-230 ◽  
Author(s):  
R. M. Duffy ◽  
B. D. Kelly
Keyword(s):  
Case Report ◽  
Side Effects ◽  
Substance Misuse ◽  
Medical Personnel ◽  
Psychotic Symptoms ◽  
Psychotic Episode ◽  
Anabolic Androgenic Steroid ◽  
Old Irish ◽  
History Of ◽  
Psychiatric Side Effects

ObjectiveTo review consequences of the changing demographic profile of anabolic-androgenic steroid (AAS) use.MethodCase report and review of key papers.ResultsWe report here a case of a 19-year-old Irish male presenting with both medical and psychiatric side effects of methandrostenolone use. The man had a long-standing history of harmful cannabis use, but had not experienced previous psychotic symptoms. Following use of methandrostenolone, he developed rhabdomyolysis and a psychotic episode with homicidal ideation.DiscussionNon-medical AAS use is a growing problem associated with medical, psychiatric and forensic risks. The population using these drugs has changed with the result of more frequent poly-substance misuse, potentially exacerbating these risks.ConclusionA higher index of suspicion is needed for AAS use. Medical personnel need to be aware of the potential side effects of their use, including the risk of violence. Research is needed to establish the magnitude of the problem in Ireland.

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