Meconium ileus: antenatal diagnosis and perinatal care

1996 ◽  
Vol 8 (2) ◽  
pp. 79-93 ◽  
Author(s):  
Michael S Irish ◽  
Yvonne Gollin ◽  
Drucy S Borowitz ◽  
Stuart O'Toole ◽  
Philip L Glick
Keyword(s):  
Cystic Fibrosis ◽  
Intestinal Obstruction ◽  
Clinical Manifestation ◽  
Antenatal Diagnosis ◽  
Perinatal Care ◽  
Meconium Ileus ◽  
Common Causes ◽  
Intestinal Obstructions

Meconium ileus (MI) is one of the most common causes of intestinal obstruction in the newborn accounting for 9–33% of neonatal intestinal obstructions. It is the earliest clinical manifestation of cystic fibrosis (CF), occurring in approximately 16% of patients with CF. However, MI has been reported in the absence of CF.

Long-term intestinal obstruction sequelae and growth in children with cystic fibrosis operated for meconium ileus: expectancies and surprises

2018 ◽  
Vol 53 (8) ◽  
pp. 1504-1508 ◽  
Author(s):  
Anastasia Mentessidou ◽  
Ioanna Loukou ◽  
Georgios Kampouroglou ◽  
Anastasia Livani ◽  
Ioannis Georgopoulos ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Intestinal Obstruction ◽  
Meconium Ileus

scholarly journals Intussusception in cat: case report

2020 ◽  
Vol 13 (6) ◽  
pp. 64
Author(s):  
J. Bartolomei Neto ◽  
A. L. Vasconcelos ◽  
A. S. Ferreira ◽  
F. S. C. Santi ◽  
W. V. Lazarotto ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Intestinal Obstruction ◽  
Foreign Bodies ◽  
Surgical Intervention ◽  
Small Animal ◽  
Electrolyte Imbalance ◽  
Common Causes ◽  
One Year ◽  
The One ◽  
Intestinal Obstructions

Intestinal obstruction is among the most common causes requiring surgical intervention in the small animal clinic. The more proximal and complete the obstruction, the more acute and intense the signs will be and the greater the likelihood of dehydration, electrolyte imbalance and even death. Among the causes of intestinal obstruction, intussusception may be the one with the highest prevalence. It is usually of idiopathic origin, has no racial and sexual predisposition, and its highest incidence is found in young animals. Predisposing factors are often associated, such as parasitism, gastroenteritis and foreign bodies where the treatment is usually surgical. In the present study we describe a case of a feline, female, one year and two months old with intestinal obstruction, presenting with four days' emesis, hypophagia, dehydration and apathy. This work aims to contribute to the knowledge and alert to a rapid differential diagnosis of intestinal obstructions which is a frequent and important disorder in the small animal clinic and is not always diagnosed in time.

Studies in Meconium: Disaccharidase Activities in Meconium From Cystic Fibrosis Patients and Controls

PEDIATRICS ◽  
1975 ◽  
Vol 56 (5) ◽  
pp. 782-787
Author(s):  
I. Antonowicz ◽  
S. Ishida ◽  
H. Shwachman
Keyword(s):  
Cystic Fibrosis ◽  
Early Diagnosis ◽  
Enzymatic Activity ◽  
Clinical Manifestation ◽  
Reducing Sugars ◽  
Specific Activity ◽  
Meconium Ileus

Meconium ileus represents the earliest clinical manifestation of cystic fibrosis. The differences found in the composition and amount of protein, mucoprotein, mucopolysaccharides, and reducing sugars in meconium from newborns with cystic fibrosis might be of significance relative to the pathogenesis and early diagnosis of this disease. We studied the enzymatic activity of disaccharidases (lactase, sucrase, maltase, and palatinase) in meconium of infants with cystic fibrosis and controls. We found an increase in the specific activity of these enzymes in the meconium from infants with cystic fibrosis as compared to the specific activity in meconium from normal infants. The increase in the activities, expressed as micromols per gram of protein per minute was: lactase, 100 times higher; sucrase, 18 times; maltase, 4.8 times; and palatinase, 8.9 times.

scholarly journals Prenatal diagnosis of meconium ileus and meconium peritonitis: Indications for cystic fibrosis testing

2011 ◽  
Vol 139 (7-8) ◽  
pp. 527-530
Author(s):  
Amira Egic ◽  
Zeljko Mikovic ◽  
Vesna Mandic ◽  
Natasa Karadzov
Keyword(s):  
Cystic Fibrosis ◽  
Intestinal Obstruction ◽  
Cytomegalovirus Infection ◽  
Chromosomal Abnormalities ◽  
Disease Risk ◽  
Prenatal Testing ◽  
Anorectal Malformations ◽  
Meconium Ileus ◽  
Meconium Peritonitis ◽  
Foetal Blood

Introduction. More recently, the regions of increased abdominal echogenicity such as echogenic bowel, meconium ileus and meconium peritonitis have been associated with an increased prevalence of a variety of unfavourable outcomes including chromosomal abnormalities, cytomegalovirus infection, intestinal obstruction, anorectal malformations and cystic fibrosis. Earlier prenatal examinations of these severe autosomal recessive diseases had been suggested only to families with history of cystic fibrosis. Recently, systemic examination has been introduced by ultrasound with bowel hyperechogenicity where the fetus is the index case for genetic disease. Risk for cystic fibrosis with this ultrasonography findings ranges from 0-33%. Outline of Cases. Two patients are presented, aged 24 and 29 years, both primigravide. The first one had ultrasonography finding of meconium peritonitis revealed at the 37th week of gestation and the other meconium ileus revealed on ultrasonography at the 29th week of gestation. Both patients had prenatal testing of foetal blood obtained by cordocenthesis, both had normal kariotype and were negative for cytomegalovirus infection. Parental DNA testing for the 2nd patient showed that parents were not carriers for the 29 most frequent mutations. Both neonates had intestinal obstruction, underwent surgery and early postoperative course was normal. Hystopathological finding suggested a possibility of cystic fibrosis for the 1st patient, but parents did not want to be tested and for the 2nd one congenital bowel stenosis as a cause of intestinal obstruction. Conclusion. Ultrasonographic echogenic bowel is an indication for invasive procedures for foetal blood testing for chromosomal abnormalities, congenital infections and parental testing for cystic fibrosis. Only if parental heterozygosity is proven foetus should be tested.

OBTURATOR HERNIA: A CASE REPORT

2016 ◽  
pp. 106-109
Author(s):  
Hoang Minh Thi Nguyen ◽  
Huu Tri Nguyen ◽  
Thanh Thao Nguyen
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Intestinal Obstruction ◽  
Key Words ◽  
Clinical Manifestation ◽  
Elderly Women ◽  
Obturator Hernia ◽  
Abdominal Hernia ◽  
Mechanical Obstruction

Obturator hernia is a rare pelvic hernia which accounts for 1% of all abdominal hernia. Clinical manifestation is ussually unspecific. Obturator hernia is often diagnosed by computed tomography or ultrasound. We present a case of obturator hernia in an elderly women who was successfully diagnosed and treated at Hue Univeristy of Medicine and Pharmacy. Key words: obturator hernia, mechanical obstruction, intestinal obstruction, Richter obturator hernia, strangulation

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