Portal vein thrombosis in Fontan-associated liver disease

2020 ◽  
Vol 30 (6) ◽  
pp. 883-885
Author(s):  
Renate Kaulitz ◽  
Ludger Sieverding ◽  
Michael Hofbeck

AbstractA 25-year-old patient with signs of cirrhosis on ultrasound and CT presented with portal vein thrombosis on routine follow-up examinations; retrograde hepatic wedge angiography demonstrated only the right-sided portal vein branch. Development of a portosystemic collateral vessel to the left-sided renal vein prevented signs of hypersplenism. This unique complication of portal vein thrombosis should be considered during long-term surveillance.

2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Paolo Magistri ◽  
Giuseppe Tarantino ◽  
Tiziana Olivieri ◽  
Annarita Pecchi ◽  
Roberto Ballarin ◽  
...  

Background. In the context of cirrhosis, portal vein thrombosis (PVT) is present in 2.1% to 26% of patients. PVT is no longer considered an absolute contraindication for liver transplantation, and nowadays, surgical strategies depend on the extent of PVT. Complete PVT is associated with higher morbidity rates and poor prognosis, while comparable long-term outcomes can be achieved as long as physiological portal inflow is restored. Materials and Methods. We report our experience with a 45-year-old patient undergoing liver transplant with a PVT (stage III-b). To restore portal vein inflow to the liver, an extra-anatomic jump graft from the right colic vein with donor iliac vein interposition was constructed. Results. The patient recovered well, with a progressive improvement of the general conditions, and was finally discharged on p.o.d. 14. No anastomotic defects were found at the postoperative CT scan 10 months after the surgery. Conclusion. Our technical innovation represents a valid and safe alternative to the cavoportal hemitransposition, providing a proper flow restoration and reproducing a physiological setting, while avoiding the complications related to the cavoportal shunt. We believe that the reconstitution of liver portal inflow should be obtained with the most physiological approach possible and considering long-term liver function.


2011 ◽  
Vol 9 (11) ◽  
pp. 2208-2214 ◽  
Author(s):  
J. HOEKSTRA ◽  
E. L. BRESSER ◽  
J. H. SMALBERG ◽  
M. C. W. SPAANDER ◽  
F. W. G. LEEBEEK ◽  
...  

2010 ◽  
Vol 90 ◽  
pp. 844
Author(s):  
A. P. Ramos ◽  
C. P.H. Reigada ◽  
E. C. Ataide ◽  
A. R. Cardoso ◽  
C. A. Caruy ◽  
...  

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Yumi Sakamoto ◽  
Keita Sato ◽  
Chieko Ishikawa ◽  
Yumiko Kagawa ◽  
Tomohiro Nakayama ◽  
...  

Abstract Background Lobular dissecting hepatitis (LDH) is a rare form of canine liver cirrhosis that may be accompanied by portal hypertension in American Cocker Spaniels. In human patients with liver cirrhosis, portal vein thrombosis (PVT) is a common complication. However, PVT has not been reported in dogs with LDH. Herein, we describe the long-term follow-up of PVT in an American Cocker Spaniel with LDH. Case presentation An 8-year-old neutered male American Cocker Spaniel presented with a 1-month history of severe abdominal effusion. The dog was histopathologically diagnosed with LDH and treated with low-dose prednisolone on day 14. On day 115, computed tomography angiography (CTA) confirmed the presence of a thrombus in the portal vein. Therefore, the dog was subcutaneously administered with the anticoagulant dalteparin, and low-dose prednisolone was continued. As a follow-up for PVT, CTA examinations were performed on days 207, 515, 886, and 1168, and the dog’s antithrombin and D-dimer levels were measured. Following anticoagulant therapy, the dog was confirmed to have gradually increased antithrombin activity and decreased D-dimer concentrations. In addition, although the thrombus was confirmed to be in the same area of the portal vein system by CTA, atrophy and increased CT values due to organization were observed during the follow-up period. The dog’s condition remained stable without clinical signs until day 1112 when it developed hepatic encephalopathy. The dog died on day 1208. On postmortem examination, histopathologically, the liver showed marked bile duct hyperplasia and fibrosis with chronic thrombus in the portal vein. Conclusions This case demonstrated that low-dose glucocorticoid combined with dalteparin allowed long-term follow-up of PVT in an American Cocker Spaniel with LDH.


2000 ◽  
Vol 6 (3) ◽  
pp. C5-C5
Author(s):  
T FISHBEIN ◽  
M BENHAIM ◽  
D HILTZIG ◽  
S EMRE ◽  
P SHEINER ◽  
...  

2008 ◽  
Vol 67 (6) ◽  
pp. 821-827 ◽  
Author(s):  
Manon C.W. Spaander ◽  
Sarwa Darwish Murad ◽  
Henk R. van Buuren ◽  
Bettina E. Hansen ◽  
Ernst J. Kuipers ◽  
...  

2017 ◽  
Vol 01 (01) ◽  
pp. 20-26
Author(s):  
Abbas Chamsuddin ◽  
Lama Nazzal ◽  
Thomas Heffron ◽  
Osama Gaber ◽  
Raja Achou ◽  
...  

AbstractIntroduction: We describe a technique we call “Meso-transjugular intrahepatic portosystemic shunt (MTIPS)” for relief of portal hypertension secondary to portal vein thrombosis (PVT) using combined surgical and endovascular technique. Materials and Methods: Nine adult patients with PVT underwent transjugular intrahepatic portosystemic shunt through a combined transjugular and mesenteric approach (MTIPS), in which a peripheral mesenteric vein was exposed through a minilaparotomy approach. The right hepatic vein was accessed through a transjugular approach. Mechanical thrombectomy, thrombolysis, and angioplasty were performed when feasible to clear PVT. Results: All patients had technically successful procedures. Patients were followed up for a mean time of 13.3 months (range: 8 days to 3 years). All patients are still alive and asymptomatic. Conclusion: We conclude that MTIPS is effective for the relief of portal hypertension secondary to PVT.


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