scholarly journals Psychiatric Pharmacogenomics: How to Integrate into Clinical Practice

CNS Spectrums ◽  
2017 ◽  
Vol 22 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Stephen M. Stahl
Keyword(s):  
Mental Health ◽  
Clinical Practice ◽  
Treatment Guidelines ◽  
Specific Treatment ◽  
Evidence Based ◽  
First Line ◽  
Specific Symptom ◽  
Symptom Profile ◽  
Evidence Based Treatments ◽  
Mental Health Practices

Pharmacogenomic testing can be integrated into modern mental health practices to help select psychotropic drugs for individuals who have failed first-line evidence-based treatments. This can be done by the process of “equipoise”—namely, balancing the weight of all available evidence. That evidence now includes not only diagnosis-specific treatment guidelines and “personalized” patient information, such as an individual’s specific symptom profile, past response to medications, side effects, family history, and patient preference, but also “precision medicine,” which incorporates the ever-expanding base of pharmacogenomic evidence for how an individual’s own biomarkers alter the odds for that individual’s treatment response or treatment intolerance.

Psychiatric disorders in refugees and immigrants

2021 ◽  
pp. 475-482
Author(s):  
J. David Kinzie
Keyword(s):  
Clinical Practice ◽  
Psychiatric Disorders ◽  
Cultural Values ◽  
Treatment Guidelines ◽  
Good Clinical Practice ◽  
Evidence Based ◽  
Treatment Goals ◽  
Dsm 5 ◽  
Evidence Based Treatments ◽  
Cultural Formulation Interview

In setting treatment goals, the patient’s cultural values and goals, as well as diagnosis, need to be considered by the clinician. Psychiatrists are urged to use the Cultural Formulation Interview of the DSM-5 to aide in assessing patients. With the impacts of globalization and ubiquitous television viewing influencing the culture of the refugees and immigrants, clearly their cultures are in flux and not static, after they arrive in the new country. Doctors and medical approaches are well known to refugees and immigrants. However, they may experience resistance and fear on referral to psychiatrists for reasons of stigma. A sensitive medical approach can help reduce the resistance and fear on the part of the refugee. When a relationship forms, psychosocial issues can be addressed. Treatment guidelines for evidence-based treatments for Western patients exist, but these should be individualized for refugees with individual goals. Good clinical practice and cultural understanding must meet the patient’s personal goals.

scholarly journals Brief Behavioural Activation (Brief BA) for Adolescent Depression: A Pilot Study

2017 ◽  
Vol 46 (2) ◽  
pp. 182-194 ◽  
Author(s):  
Laura Pass ◽  
Carl W. Lejuez ◽  
Shirley Reynolds
Keyword(s):  
Mental Health ◽  
Pilot Study ◽  
Young People ◽  
Adolescent Depression ◽  
Psychological Intervention ◽  
Clinical Effectiveness ◽  
Evidence Based ◽  
Behavioural Activation ◽  
Evidence Based Treatments ◽  
The Uk

Background: Depression in adolescence is a common and serious mental health problem. In the UK, access to evidence-based psychological treatments is limited, and training and employing therapists to deliver these is expensive. Brief behavioural activation for the treatment of depression (BATD) has great potential for use with adolescents and to be delivered by a range of healthcare professionals, but there is limited empirical investigation with this group. Aims: To adapt BATD for depressed adolescents (Brief BA) and conduct a pilot study to assess feasibility, acceptability and clinical effectiveness. Method: Twenty depressed adolescents referred to the local NHS Child and Adolescent Mental Health service (CAMHs) were offered eight sessions of Brief BA followed by a review around one month later. Self- and parent-reported routine outcome measures (ROMs) were collected at every session. Results: Nineteen of the 20 young people fully engaged with the treatment and all reported finding some aspect of Brief BA helpful. Thirteen (65%) required no further psychological intervention following Brief BA, and both young people and parents reported high levels of acceptability and satisfaction with the approach. The pre–post effect size of Brief BA treatment was large. Conclusions: Brief BA is a promising innovation in the treatment of adolescent depression. This approach requires further evaluation to establish effectiveness and cost effectiveness compared with existing evidence-based treatments for adolescent depression. Other questions concern the effectiveness of delivery in other settings and when delivered by a range of professionals.

scholarly journals Psychiatry in the future

2004 ◽  
Vol 28 (8) ◽  
pp. 277-278
Author(s):  
Frank Holloway
Keyword(s):  
Mental Health ◽  
Clinical Practice ◽  
Evidence Based Medicine ◽  
Cochrane Collaboration ◽  
Routine Clinical Practice ◽  
Evidence Based ◽  
Policy Makers ◽  
The Future ◽  
The Cochrane Collaboration ◽  
Based Medicine

In an era of evidence-based medicine, policy-makers and researchers are preoccupied by the task of ensuring that advances in research are implemented in routine clinical practice. This preoccupation has spawned a small but growing research industry of its own, with the development of resources such as the Cochrane Collaboration database and journals such as Evidence-Based Mental Health. In this paper, I adopt a philosophically quite unfashionable methodology – introspection – to address the question: how has research affected my practice?

scholarly journals Correction to: The Effect of a Change Agent on Use of Evidence-Based Mental Health Practices

2018 ◽  
Vol 45 (3) ◽  
pp. 518-518
Author(s):  
Sonya J. Leathers ◽  
Jill E. Spielfogel ◽  
Joan Blakey ◽  
Errick Christian ◽  
Marc S. Atkins
Keyword(s):  
Mental Health ◽  
Change Agent ◽  
Evidence Based ◽  
Health Practices ◽  
Mental Health Practices

scholarly journals Disseminating evidence-based mental health practices

2003 ◽  
Vol 6 (1) ◽  
pp. 4-5 ◽  
Author(s):  
P. Corrigan ◽  
S. McCracken ◽  
B. Blaser
Keyword(s):  
Mental Health ◽  
Evidence Based ◽  
Health Practices ◽  
Mental Health Practices
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