Online Process Control of a Pharmaceutical Intermediate in a Fluidized-Bed Drier Environment Using Near-Infrared Spectroscopy

2010 ◽  
Vol 82 (10) ◽  
pp. 4209-4215 ◽  
Author(s):  
Julia Märk ◽  
Martin Karner ◽  
Max Andre ◽  
Jochen Rueland ◽  
Christian W. Huck
Keyword(s):  
Infrared Spectroscopy ◽  
Process Control ◽  
Fluidized Bed ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Online Process

Online process control of alkaline texturing baths with near-infrared spectroscopy

2010 ◽  
Vol 53 (2) ◽  
pp. 269-273 ◽  
Author(s):  
Martin Zimmer ◽  
Katrin Birmann ◽  
Jochen Rentsch
Keyword(s):  
Infrared Spectroscopy ◽  
Process Control ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Online Process

scholarly journals Application of Near-Infrared Spectroscopy Analysis Technology to Total Nucleosides Quality Control in the Fermented Cordyceps Powder Production Process

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Tiannv Shi ◽  
Yongmei Guan ◽  
Lihua Chen ◽  
Shiyu Huang ◽  
Weifeng Zhu ◽  
...  
Keyword(s):  
Quality Control ◽  
Infrared Spectroscopy ◽  
Production Process ◽  
Process Monitoring ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Powder Preparation ◽  
Spectroscopy Analysis ◽  
Online Process Monitoring ◽  
Online Process

Product quality control is a prerequisite for ensuring safety, effectiveness, and stability. However, because of the different strain species and fermentation processes, there was a significant difference in quality. As a result, they should be clearly distinguished in clinical use. Among them, the fermentation process is critical to achieving consistent product quality. This study aims to introduce near-infrared spectroscopy analysis technology into the production process of fermented Cordyceps powder, including strain culture, strain passage, strain fermentation, strain filtration, strain drying, strain pulverizing, and strain mixing. First, high performance liquid chromatography (HPLC) was used to measure the total nucleosides content in the production process of 30 batches of fermented Cordyceps powder, including uracil, uridine, adenine, guanosine, adenosine, and the process stability and interbatch consistency were analyzed with traditional Chinese medicine (TCM) fingerprinting, followed by the near-infrared spectroscopy (NIRS) combined with partial least squares regression (PLSR) to establish a quantitative analysis model of total nucleosides for online process monitoring of fermented Cordyceps powder preparation products. The model parameters indicate that the established model with good robustness and high measurement precision. It further clarifies that the model can be used for online process monitoring of fermented Cordyceps powder preparation products.

Process Control of Antithrombin III Production by Near-Infrared Spectroscopy

1997 ◽  
pp. 417-421 ◽  
Author(s):  
Sven Harthun ◽  
Kathrin Matischak ◽  
Peter Friedl
Keyword(s):  
Infrared Spectroscopy ◽  
Process Control ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Antithrombin Iii

Determination of fluidized bed granulation end point using near‐infrared spectroscopy and phenomenological analysis

2005 ◽  
Vol 94 (3) ◽  
pp. 604-612 ◽  
Author(s):  
W. Paul Findlay ◽  
Garnet R. Peck ◽  
Kenneth R. Morris
Keyword(s):  
Infrared Spectroscopy ◽  
Fluidized Bed ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Phenomenological Analysis ◽  
End Point

Near-infrared spectroscopy for process control and optimization of biogas plants

2010 ◽  
Vol 10 (6) ◽  
pp. 537-543 ◽  
Author(s):  
Stefan Luck ◽  
Gabriele Büge ◽  
Holger Plettenberg ◽  
Martin Hoffmann
Keyword(s):  
Infrared Spectroscopy ◽  
Process Control ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Biogas Plants

Online Real-Time Monitoring of Moisture in Pharmaceutical Granules During Fluidized Bed Drying Using Near-Infrared Spectroscopy

Yakhak Hoeji ◽  
2016 ◽  
Vol 60 (2) ◽  
pp. 85-91
Author(s):  
Jaejin Kim ◽  
◽  
Byung-Suk Kim ◽  
Young-Il Lim ◽  
Young-Ah Woo ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Real Time ◽  
Fluidized Bed ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Real Time Monitoring ◽  
Fluidized Bed Drying

Transfer of a near infrared spectroscopy laboratory application to an online process analyser for in situ monitoring of anaerobic digestion

2013 ◽  
Vol 129 ◽  
pp. 39-50 ◽  
Author(s):  
L. Christian Krapf ◽  
Dieter Nast ◽  
Andreas Gronauer ◽  
Urs Schmidhalter ◽  
Hauke Heuwinkel
Keyword(s):  
Infrared Spectroscopy ◽  
Anaerobic Digestion ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
In Situ Monitoring ◽  
Online Process
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