Synthetic Route to Enaminones via Metal-Free Four-Component Sequential Reactions of Aryl Olefins with CHCl3, Et3N, and TBHP

2021 ◽  
Author(s):  
Jiantao Zhang ◽  
Peng Zhou ◽  
Aiguo Yin ◽  
Shuhua Zhang ◽  
Weibing Liu
Keyword(s):  
Synthetic Route ◽  
Metal Free ◽  
Aryl Olefins ◽  
Sequential Reactions

Organic Photoredox Catalysis for Pschorr Reaction: A Metal-Free and Mild Approach to 6H-Benzo[c]chromenes

Synlett ◽  
2018 ◽  
Vol 29 (17) ◽  
pp. 2311-2315 ◽  
Author(s):  
Gaofeng Feng ◽  
Jing-Yao He ◽  
Qi-Fan Bai ◽  
Chengan Jin
Keyword(s):  
Diazonium Salts ◽  
Eosin Y ◽  
Photoredox Catalysis ◽  
Synthetic Route ◽  
Metal Free ◽  
Mild Conditions ◽  
Pschorr Reaction

An expedient organic photoredox Pschorr reaction has been developed that opens up a synthetic route to 6H-benzo[c]chromenes. The process can be performed under mild conditions by using eosin Y as a photoredox catalyst and acetonitrile as the solvent. The diazonium salts can be either preformed or generated in situ from the corresponding amines with t-BuONO. The process is amenable to gram-sale synthesis of 6H-benzo[c]chromenes, which can be further transformed into both 6H-benzo[c]chromen-6-ones through oxidation or to 6H-benzo[c]chromen-6-amine through sp3 C–H bond amination. The protocol provides an attractive route for the synthesis of a library of 6H-benzo[c]chromes.

A metal-free heterogeneous photocatalyst for the selective oxidative cleavage of CC bonds in aryl olefins via harvesting direct solar energy

2020 ◽  
Vol 22 (14) ◽  
pp. 4516-4522 ◽  
Author(s):  
Yu Zhang ◽  
Nareh Hatami ◽  
Niklas Simon Lange ◽  
Emanuel Ronge ◽  
Waldemar Schilling ◽  
...  
Keyword(s):  
Solar Energy ◽  
Oxidative Cleavage ◽  
Metal Free ◽  
Carbon Nitrides ◽  
Aryl Olefins ◽  
Polymeric Carbon

A mild protocol has been developed using polymeric carbon nitrides (PCN) as metal-free heterogeneous photocatalyst to convert olefins into the corresponding carbonyls which even can be applied in the gram scale synthesis using direct solar energy.

ChemInform Abstract: Green Chemistry: Solvent- and Metal-Free Prins Cyclization. Application to Sequential Reactions.

ChemInform ◽  
2012 ◽  
Vol 43 (17) ◽  
pp. no-no
Author(s):  
Damien Clarisse ◽  
Beatrice Pelotier ◽  
Olivier Piva ◽  
Fabienne Fache
Keyword(s):  
Green Chemistry ◽  
Prins Cyclization ◽  
Metal Free ◽  
Sequential Reactions

A Synthetic Route to Metal-free Corrins

1967 ◽  
Vol 6 (10) ◽  
pp. 866-868 ◽  
Author(s):  
A. Fischli ◽  
A. Eschenmoser
Keyword(s):  
Synthetic Route ◽  
Metal Free

ChemInform Abstract: An Expeditious and Metal-Free Synthetic Route Towards Quinolones, Naphthyridones and Benzonaphthyridones.

ChemInform ◽  
2015 ◽  
Vol 46 (17) ◽  
pp. no-no
Author(s):  
Napoleon John Victor ◽  
Kannoth Manheri Muraleedharan
Keyword(s):  
Synthetic Route ◽  
Metal Free

Application of primary halogenated hydrocarbons for the synthesis of 3-aryl and 3-alkyl indolizines

2017 ◽  
Vol 15 (23) ◽  
pp. 5016-5024 ◽  
Author(s):  
Yan Liu ◽  
Huayou Hu ◽  
Junyu Zhou ◽  
Wenhui Wang ◽  
Youliang He ◽  
...  
Keyword(s):  
Transition Metal ◽  
Halogenated Hydrocarbons ◽  
Tandem Reaction ◽  
Synthetic Route ◽  
Metal Free ◽  
First Time

A transition-metal-free synthetic route to 3-aryl and 3-alkyl indolizines from electron-deficient alkenes, pyridines and primary halogenated hydrocarbons is reported for the first time using a tandem reaction.

A New Protocol for Total Synthesis of Natural Product Frutinone A and Its Derivatives

2016 ◽  
Vol 69 (1) ◽  
pp. 98 ◽  
Author(s):  
Kang Lei ◽  
Dong-Wei Sun ◽  
Yuan-Yuan Tao ◽  
Xiao-Hua Xu
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Good Yield ◽  
Substitution Reaction ◽  
High Tolerance ◽  
Synthetic Route ◽  
Reaction Conditions ◽  
One Pot ◽  
Metal Free ◽  
Intramolecular Nucleophilic Substitution

A new protocol for total synthesis of natural product frutinone A was accomplished in three steps by using inexpensive 2′-hydroxyacetophenone as starting material. The key intermediate 3-(2-chlorobenzoyl)-4-hydroxycoumarin was synthesized in one pot through Baker–Venkataraman rearrangement of 2-acetylphenyl 2-chlorobenzoate followed by introduction of methyl chloroformate under basic conditions. Then, base-promoted intramolecular nucleophilic substitution reaction of 3-(2-chlorobenzoyl)-4-hydroxycoumarin provided frutinone A in excellent yield. The synthetic route features good yield, transition metal-free and mild reaction conditions, and high tolerance for functionality, thereby allowing easy substitutions around the frutinone A core.

N- and O-doped mesoporous carbons derived from rice grains: efficient metal-free electrocatalysts for hydrazine oxidation

2016 ◽  
Vol 52 (93) ◽  
pp. 13588-13591 ◽  
Author(s):  
Katherine Koh ◽  
Yuying Meng ◽  
Xiaoxi Huang ◽  
Xiaoxin Zou ◽  
Manish Chhowalla ◽  
...  
Keyword(s):  
Hydrothermal Synthesis ◽  
Mesoporous Carbon ◽  
Oxidation Reaction ◽  
Mesoporous Carbons ◽  
Synthetic Route ◽  
Metal Free ◽  
Rice Grains ◽  
Highly Efficient ◽  
Hydrazine Oxidation ◽  
First Time

A novel synthetic route, combining hydrothermal synthesis, templating and pyrolysis, is demonstrated for the first time on biomass to produce highly efficient, metal-free mesoporous carbon electrocatalysts for the hydrazine oxidation reaction.

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