Panitumumab Modified with Metal-Chelating Polymers (MCP) Complexed to 111In and 177Lu—An EGFR-Targeted Theranostic for Pancreatic Cancer

2018 ◽  
Vol 15 (3) ◽  
pp. 1150-1159 ◽  
Author(s):  
Sadaf Aghevlian ◽  
Yijie Lu ◽  
Mitchell A. Winnik ◽  
David W. Hedley ◽  
Raymond M. Reilly
Keyword(s):  
Pancreatic Cancer ◽  
Metal Chelating ◽  
Chelating Polymers

scholarly journals EGFR-Targeted Metal Chelating Polymers (MCPs) Harboring Multiple Pendant PEG2K Chains for MicroPET/CT Imaging of Patient-Derived Pancreatic Cancer Xenografts

2017 ◽  
Vol 3 (3) ◽  
pp. 279-290 ◽  
Author(s):  
Yijie Lu ◽  
Amanda J. Boyle ◽  
Ping-Jiang Cao ◽  
David Hedley ◽  
Raymond M. Reilly ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Ct Imaging ◽  
Metal Chelating ◽  
Chelating Polymers

Radioimmunotherapy of PANC-1 Human Pancreatic Cancer Xenografts in NRG Mice with Panitumumab Modified with Metal-Chelating Polymers Complexed to177Lu

2018 ◽  
Vol 16 (2) ◽  
pp. 768-778 ◽  
Author(s):  
Sadaf Aghevlian ◽  
Zhongli Cai ◽  
Yijie Lu ◽  
David W. Hedley ◽  
Mitchell A. Winnik ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Human Pancreatic Cancer ◽  
Metal Chelating ◽  
Chelating Polymers

Site-Specific Conjugation of Metal-Chelating Polymers to Anti-Frizzled-2 Antibodies via Microbial Transglutaminase

2021 ◽  
Author(s):  
Penny J. Le ◽  
Shane Miersch ◽  
Matthew W. Forbes ◽  
Nick Jarvik ◽  
Anthony Ku ◽  
...  
Keyword(s):  
Microbial Transglutaminase ◽  
Site Specific ◽  
Metal Chelating ◽  
Chelating Polymers

Metal-Chelating Polymers by Anionic Ring-Opening Polymerization and Their Use in Quantitative Mass Cytometry

2012 ◽  
Vol 13 (8) ◽  
pp. 2359-2369 ◽  
Author(s):  
Nicolas Illy ◽  
Daniel Majonis ◽  
Isaac Herrera ◽  
Olga Ornatsky ◽  
Mitchell A. Winnik
Keyword(s):  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Mass Cytometry ◽  
Metal Chelating ◽  
Anionic Ring ◽  
Chelating Polymers

Assessing the effects of model Maillard compound intake on iron, copper and zinc retention and tissue delivery in adult rats

2016 ◽  
Vol 7 (1) ◽  
pp. 164-170 ◽  
Author(s):  
Irene Roncero-Ramos ◽  
Silvia Pastoriza ◽  
M. Pilar Navarro ◽  
Cristina Delgado-Andrade
Keyword(s):  
Maillard Reaction ◽  
Adult Rats ◽  
Mineral Absorption ◽  
Metal Chelating ◽  
Iron Copper ◽  
Copper And Zinc ◽  
Zinc Retention ◽  
Chelating Polymers

The behaviour of dietary Maillard reaction compounds (MRP) as metal chelating polymers can alter mineral absorption and/or retention.

Metal-Chelating Polymers (MCPs) with Zwitterionic Pendant Groups Complexed to Trastuzumab Exhibit Decreased Liver Accumulation Compared to Polyanionic MCP Immunoconjugates

2015 ◽  
Vol 16 (11) ◽  
pp. 3613-3623 ◽  
Author(s):  
Peng Liu ◽  
Amanda J. Boyle ◽  
Yijie Lu ◽  
Jarrett Adams ◽  
Yuechuan Chi ◽  
...  
Keyword(s):  
Metal Chelating ◽  
Chelating Polymers

Stability and Biodistribution of Thiol-Functionalized and177Lu-Labeled Metal Chelating Polymers Bound to Gold Nanoparticles

2016 ◽  
Vol 17 (4) ◽  
pp. 1292-1302 ◽  
Author(s):  
Simmyung Yook ◽  
Yijie Lu ◽  
Jenny Jooyoung Jeong ◽  
Zhongli Cai ◽  
Lemuel Tong ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Metal Chelating ◽  
Chelating Polymers

Biotinylated Polyacrylamide-Based Metal-Chelating Polymers and Their Influence on Antigen Recognition Following Conjugation to a Trastuzumab Fab Fragment

2012 ◽  
Vol 13 (9) ◽  
pp. 2831-2842 ◽  
Author(s):  
Peng Liu ◽  
Amanda J. Boyle ◽  
Yijie Lu ◽  
Raymond M. Reilly ◽  
Mitchell A. Winnik
Keyword(s):  
Antigen Recognition ◽  
Fab Fragment ◽  
Metal Chelating ◽  
Chelating Polymers
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