surface modification
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Author(s):  
Siti Nurul Akmal Yusof ◽  
Nura Mu'az Muhammad ◽  
Wan Mohd Arif Aziz Japar ◽  
Yutaka Asako ◽  
Chungpyo Hong ◽  
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2022 ◽  
Vol 579 ◽  
pp. 152129
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Haiyun Xie ◽  
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Pei Zhang ◽  
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2022 ◽  
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2022 ◽  
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Omolola Eniola‐Adefeso

2022 ◽  
Vol 23 (2) ◽  
pp. 932
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Dmitry V. Korolev ◽  
Galina A. Shulmeyster ◽  
Natalia V. Evreinova ◽  
Maria S. Syrovatkina ◽  
Maria S. Istomina ◽  
...  

In this paper, we describe the synthesis of multilayer nanoparticles as a platform for the diagnosis and treatment of ischemic injuries. The platform is based on magnetite (MNP) and silica (SNP) nanoparticles, while quinacrine is used as an anti-ischemic agent. The synthesis includes the surface modification of nanoparticles with (3-glycidyloxypropyl)trimethoxysilane (GPMS), the immobilization of quinacrine, and the formation of a chitosan coating, which is used to fix the fluorophore indocyanine green (ICG) and colloidal quantum dots AgInS2/ZnS (CQDs), which serve as secondary radiation sources. The potential theranostic platform was studied in laboratory animals.


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