AbstractAsymmetric hydroboration of simple and unactivated terminal alkenes (α-olefins), feedstock chemicals derived from the petrochemical industry, has not been efficiently realized for past decades. Using a bulky ANIPE ligand, we achieved a rare example of highly enantioselective copper-catalyzed Markovnikov hydroboration of α-olefins. The chiral secondary alkylboronic ester products were obtained in moderate to good yields and regioselectivities with excellent enantioselectivities.1 Introduction2 Conditions Optimization3 Substrate Scope4 Application5 Mechanistic Discussion6 Conclusions and Future Directions
<p>One facile and efficient strategy for the hydrosilylation of steric 1,1-disubstituted
terminal alkenes is demonstrated. Investigations on substrate scope and control
experiments revealed the necessity of thioether in promoting this process under
a simple iridium catalysis system. This convenient and feasible method is
expected to be useful in the synthesis of sulfur-containing organosilicon
polymers with different side-chains.</p><p><br></p>
A Rh(III) catalyzed allylic C H amidation of substituted alkenes with in situ generated iminoiodinanes is demonstrated. The present protocol is compatible with differently functionalized unactivated terminal alkenes and internal...
The palladium-catalyzed 1,1-alkynylbromination of terminal alkenes with a silyl-protected alkynyl bromide is reported. The method tolerates a diverse range of alkenes including vinylarenes, acrylates, and even electronically unbiased alkene derivatives...
The ruthenium carbene pincer complex 2 was synthesized treating the benzo annulated cycloheptatriene bisphosphine 1 with RuCl3. Addition of three equivalents of hydrogen to the carbocyclic carbene complex 2 was...
A metal-free oxidative alkene alkylation/alkynylation of 1,4-enyn-3-ols with alkylaldehydes has been achieved, which offers a general access to the challenging quaternary carbon-containing but-3-yn-1-ones. The method features with excellent functional group...
Palladium-catalyzed 1,1-alkynylbromination of alkenes with alkynyl bromides