Electron Donor–Acceptor Effect-Induced Organic/Inorganic Nanohybrids with Low Energy Gap for Highly Efficient Photothermal Therapy

Author(s):  
Guiju Zhang ◽  
Kunle Li ◽  
Shan He ◽  
Li Wang ◽  
Shanyue Guan ◽  
...  
2019 ◽  
Vol 55 (61) ◽  
pp. 8967-8970 ◽  
Author(s):  
Yu Cai ◽  
Zheng Wei ◽  
Chuanhui Song ◽  
Chuanchao Tang ◽  
Xiaoyu Huang ◽  
...  

Acceptor–donor–acceptor structured ITIC small molecule based nanoparticles are explored for highly efficient photothermal therapy application.


2015 ◽  
Vol 51 (87) ◽  
pp. 15796-15799 ◽  
Author(s):  
Mikihiro Hayashi ◽  
Kazuya Otsubo ◽  
Tatsuhisa Kato ◽  
Kunihisa Sugimoto ◽  
Akihiko Fujiwara ◽  
...  

We prepared a compact, planar, low-energy-gap molecule with donor–acceptor–donor (D–A–D) nature for the first time based on a bimetal dithiolene complex.


2013 ◽  
Vol 1 (16) ◽  
pp. 5165 ◽  
Author(s):  
Abdulaziz A. B. Alghamdi ◽  
Darren C. Watters ◽  
Hunan Yi ◽  
Solyman Al-Faifi ◽  
Mohammed S. Almeataq ◽  
...  

2020 ◽  
Author(s):  
José Tiago Menezes Correia ◽  
Gustavo Piva da Silva ◽  
Camila Menezes Kisukuri ◽  
Elias André ◽  
Bruno Pires ◽  
...  

A metal- and catalyst-free photoinduced radical cascade hydroalkylation of 1,7-enynes has been disclosed. The process is triggered by a SET event involving a photoexcited electron-donor-aceptor complex between NHPI ester and Hantzsch ester, which decomposes to afford a tertiary radical that is readily trapped by the enyne. <a>The method provides an operationally simple, robust and step-economical approach to the construction of diversely functionalized dihydroquinolinones bearing quaternary-centers. A sequential one-pot hydroalkylation-isomerization approach is also allowed giving access to a family of quinolinones. A wide substrate scope and high functional group tolerance was observed in both approaches</a>.


2020 ◽  
Author(s):  
zhihong sun ◽  
Guanjun Deng ◽  
Xinghua Peng ◽  
Xiuli Xu ◽  
Lanlan Liu ◽  
...  

Recently, photothermal-immuno synergistic therapy under mild temperature (~ 45 °C) has got broad interest in cancer treatment. Inhibition the intratumorally HSPs production is the key to accomplish highly efficient and mild photothermal therapy. In this work, we developed biomimetic nanoterminators with mature DCs functions by coating the mature dendritic cell membrane on photothermal nanoagents. As-prepared nanoterminators could automatically locate on T cell in the complex tumor-immune microenvironment and promote the T cells proliferation, activation and cytokine secretion, which could not only inhibit the expression of heat shock proteins to cooperate on highly efficient mild photothermal therapy (~42°C), but also promote tumor apoptosis during the treatment. More importantly, this nanoterminator could serve as vaccine to trigger anti-tumor immune response of the whole body, which would be promising to long-life tumor inhibition and termination.


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