Silencing of Pyruvate Kinase M2 via a Metal–Organic Framework Based Theranostic Gene Nanomedicine for Triple-Negative Breast Cancer Therapy

2021 ◽  
Author(s):  
Siming Huang ◽  
Wangshu Zhu ◽  
Fang Zhang ◽  
Guosheng Chen ◽  
Xiaoxue Kou ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Therapy ◽  
Pyruvate Kinase ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Metal Organic Framework ◽  
Breast Cancer Therapy ◽  
Pyruvate Kinase M2 ◽  
Metal Organic ◽  
Organic Framework

Fabrication of curcumin-loaded folic acid-tagged metal organic framework for triple negative breast cancer therapy inin vitroandin vivosystems

2019 ◽  
Vol 43 (1) ◽  
pp. 217-229 ◽  
Author(s):  
Dipranjan Laha ◽  
Kunal Pal ◽  
Angshuman Ray Chowdhuri ◽  
Pravat Kumar Parida ◽  
Sumanta Kumar Sahu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Folic Acid ◽  
Cancer Therapy ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Metal Organic Framework ◽  
Free Drug ◽  
Therapeutic Activity ◽  
Breast Cancer Therapy ◽  
Metal Organic

Curcumin has shown therapeutic activity against triple-negative breast cancer (TNBC) cells, but it shows low efficacy and low bioavailability when administered as a free drug.

Multicomponent-assembled nanodiamond hybrids for targeted and imaging guided triple-negative breast cancer therapy via a ternary collaborative strategy

2021 ◽  
Author(s):  
Xinyue Cui ◽  
Xiongwei Deng ◽  
Zhaoyuan Liang ◽  
Jianqing Lu ◽  
Leihou Shao ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Therapy ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Breast Cancer Therapy

A multicomponent-assembled nanodiamond hybrid theranostic nanoplatform exhibits Cur/PDT/PTT ternary collaborative triple-negative breast cancer therapy via curcumin and IR780 co-delivery.

scholarly journals Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy

2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Yu-Cheng Su ◽  
Pierre-Alain Burnouf ◽  
Kuo-Hsiang Chuang ◽  
Bing-Mae Chen ◽  
Tian-Lu Cheng ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Therapy ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Breast Cancer Therapy

Selective Inhibition of Lysine‐Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple‐Negative Breast Cancer Therapy

2018 ◽  
Vol 130 (40) ◽  
pp. 13275-13279 ◽  
Author(s):  
Guan‐Jun Yang ◽  
Wanhe Wang ◽  
Simon Wing Fai Mok ◽  
Chun Wu ◽  
Betty Yuen Kwan Law ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Therapy ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Selective Inhibition ◽  
Breast Cancer Therapy ◽  
Lysine Specific Demethylase
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