Dendrimer-Modified MoS2 Nanoflakes as a Platform for Combinational Gene Silencing and Photothermal Therapy of Tumors

2017 ◽  
Vol 9 (19) ◽  
pp. 15995-16005 ◽  
Author(s):  
Lingdan Kong ◽  
Lingxi Xing ◽  
Benqing Zhou ◽  
Lianfang Du ◽  
Xiangyang Shi
Keyword(s):  
Gene Silencing ◽  
Photothermal Therapy

The nanomedicine system has successfully inhibited tumor neovascularization using gene silencing, chemotherapy, photothermal therapy, and other therapies

2021 ◽  
Author(s):  
Moataz Dowaidar
Keyword(s):  
Treatment Outcome ◽  
Gene Silencing ◽  
Large Volume ◽  
Photothermal Therapy ◽  
Tumor Model ◽  
Vascular Wall ◽  
Tumor Treatment ◽  
Physical Methods ◽  
Vascular Disruption ◽  
Tumor Neovascularization

Customized nanomedicines can be used in a variety of ways, including angiogenesis suppression, vascular disruption, and vascular infarction. In the angiogenesis suppression approach, VEGF, VEGFR, mTOR, EGFR, bFGF, ROS, and other components have become promising therapeutic targets. The nanomedicine system has successfully inhibited tumor neovascularization using gene silencing, chemotherapy, photothermal therapy, and other therapies. In the vascular disruption approach, VDAs supplied by nanomaterials were bonded with the bonding sites of CA4, COL, PTX, and other medications on microtubules to promote rapid disintegration of tumor vascular wall cells. Combining many medicines increased the tumor treatment outcome even more. For example, disruption of tumor blood arteries caused by nanoparticle-mediated physical methods combined with chemotherapy resulted in effective treatment in a large volume tumor model. The vascular infarction methodology uses a variety of carriers, including nanoparticles, DNA nanorobots, platelet membranes, and others, to carry thrombin, tTF, and other drugs to generate local thrombosis and provide safe and effective tumor treatment.

Gold-nanorods-siRNA nanoplex for improved photothermal therapy by gene silencing

Biomaterials ◽  
2016 ◽  
Vol 78 ◽  
pp. 27-39 ◽  
Author(s):  
Bei-Ke Wang ◽  
Xue-Feng Yu ◽  
Jia-Hong Wang ◽  
Zhi-Bin Li ◽  
Peng-Hui Li ◽  
...  
Keyword(s):  
Gene Silencing ◽  
Gold Nanorods ◽  
Photothermal Therapy

scholarly journals Multifunctional Gold Nanorods for siRNA Gene Silencing and Photothermal Therapy

2014 ◽  
Vol 3 (10) ◽  
pp. 1629-1637 ◽  
Author(s):  
Jianliang Shen ◽  
Han-Cheon Kim ◽  
Chaofeng Mu ◽  
Emanuela Gentile ◽  
Junhua Mai ◽  
...  
Keyword(s):  
Gene Silencing ◽  
Gold Nanorods ◽  
Photothermal Therapy

Dendrimer-Stabilized Gold Nanostars as a Multifunctional Theranostic Nanoplatform for CT Imaging, Photothermal Therapy, and Gene Silencing of Tumors

2016 ◽  
Vol 5 (24) ◽  
pp. 3203-3213 ◽  
Author(s):  
Ping Wei ◽  
Jingwen Chen ◽  
Yong Hu ◽  
Xin Li ◽  
Han Wang ◽  
...  
Keyword(s):  
Gene Silencing ◽  
Photothermal Therapy ◽  
Ct Imaging ◽  
Gold Nanostars

Synergic therapy of melanoma using GNRs-MUA-PEI/siIDO2-FA through targeted gene silencing and plasmonic photothermia

RSC Advances ◽  
2016 ◽  
Vol 6 (81) ◽  
pp. 77577-77589 ◽  
Author(s):  
Yujuan Zhang ◽  
Na Song ◽  
Jiamin Fu ◽  
Yanling Liu ◽  
Xuelin Zhan ◽  
...  
Keyword(s):  
Gene Silencing ◽  
Photothermal Therapy

IDO2 siRNA synergizes GNR-mediated anti-melanoma photothermal therapy.

A novel multifunctional gold nanorod-mediated and tumor-targeted gene silencing of GPC-3 synergizes photothermal therapy for liver cancer

2021 ◽  
Vol 32 (17) ◽  
pp. 175101
Author(s):  
Yanling Liu ◽  
Manman Tan ◽  
Chunjuan Fang ◽  
Xiaoyan Chen ◽  
Huan Liu ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Gene Silencing ◽  
Photothermal Therapy ◽  
Gold Nanorod

968: Gelsolin Gene Silencing Involving Unusual Chromatin Structures and a Novel Stem Loop Structure of the Promoter Region in Human Bladder Cancer

2004 ◽  
Vol 171 (4S) ◽  
pp. 256-257
Author(s):  
Kazunori Haga ◽  
Ataru Sazawa ◽  
Toru Harabayashi ◽  
Nobuo Shinohara ◽  
Minoru Nomoto ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Gene Silencing ◽  
Promoter Region ◽  
Loop Structure ◽  
Human Bladder Cancer ◽  
Human Bladder ◽  
Stem Loop ◽  
Stem Loop Structure
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