A straightforward and efficient synthesis of acridine derivatives via a copper-catalyzed cascade
reaction among isoxazoles and diaryliodonium salts is achieved. Various mono-, multi-substituted
and 9-substituted acridine derivatives could be obtained in moderate to good yields. The process has
gone through tandem double arylation and Friedel-Crafts reactions.
AbstractA copper-catalyzed tandem reaction has been developed for the synthesis of 1,2,3-triazole-fused indole derivatives. This protocol allowed us to access a wide range of 1,2,3-triazole-fused indole derivatives in moderate to excellent yields. The 1,2,3-triazole-fused indole derivatives emit blue and greenish light when excited at 365 nm. The products were further explored for their quantum efficiency and photophysical properties.
Reactions of alkynoates with different types of radical precursors under metal-free conditions affording single-site-addition poly-substituted alkenes were reported.
Synthesis of Carbazoles by a Diverted Bischler–Napieralski Cascade Reaction
