Novel Water-Soluble Near-Infrared Cyanine Dyes:  Synthesis, Spectral Properties, and Use in the Preparation of Internally Quenched Fluorescent Probes

2007 ◽  
Vol 18 (4) ◽  
pp. 1303-1317 ◽  
Author(s):  
Cédric Bouteiller ◽  
Guillaume Clavé ◽  
Aude Bernardin ◽  
Bertrand Chipon ◽  
Marc Massonneau ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
Spectral Properties ◽  
Near Infrared ◽  
Cyanine Dyes ◽  
Water Soluble

Syntheses, spectral properties and photostabilities of novel water-soluble near-infrared cyanine dyes

2004 ◽  
Vol 168 (1-2) ◽  
pp. 53-57 ◽  
Author(s):  
Fengling Song ◽  
Xiaojun Peng ◽  
Erhu Lu ◽  
Rong Zhang ◽  
Xiuying Chen ◽  
...  
Keyword(s):  
Spectral Properties ◽  
Near Infrared ◽  
Cyanine Dyes ◽  
Water Soluble

Synthesis of water-soluble near-infrared cyanine dyes functionalized with [(succinimido)oxy]carbonyl group

2003 ◽  
Vol 40 (5) ◽  
pp. 913-916 ◽  
Author(s):  
Lucjan Strekowski ◽  
Christian J. Mason ◽  
Hyeran Lee ◽  
Rajni Gupta ◽  
John Sowell ◽  
...  
Keyword(s):  
Carbonyl Group ◽  
Near Infrared ◽  
Cyanine Dyes ◽  
Water Soluble

Synthesis of Water-Soluble Near-Infrared Cyanine Dyes Functionalized with [(Succinimido)oxy]carbonyl Group.

ChemInform ◽  
2004 ◽  
Vol 35 (11) ◽  
Author(s):  
Lucjan Strekowski ◽  
Christian J. Mason ◽  
Hyeran Lee ◽  
Rajni Gupta ◽  
John Sowell ◽  
...  
Keyword(s):  
Carbonyl Group ◽  
Near Infrared ◽  
Cyanine Dyes ◽  
Water Soluble

Water-soluble pH-sensitive 2,6-bis(substituted ethylidene)-cyclohexanone/hydroxy cyanine dyes that absorb in the visible/near-infrared regions

2004 ◽  
Vol 41 (2) ◽  
pp. 227-232 ◽  
Author(s):  
Lucjan Strekowski ◽  
J. Christian Mason ◽  
Hyeran Lee ◽  
Martial Say ◽  
Gabor Patonay
Keyword(s):  
Near Infrared ◽  
Cyanine Dyes ◽  
Ph Sensitive ◽  
Water Soluble

Molecular Design Strategies for Near-Infrared Ratiometric Fluorescent Probes Based on the Unique Spectral Properties of Aminocyanines

2009 ◽  
Vol 15 (36) ◽  
pp. 9191-9200 ◽  
Author(s):  
Kazuki Kiyose ◽  
Sakiko Aizawa ◽  
Eita Sasaki ◽  
Hirotatsu Kojima ◽  
Kenjiro Hanaoka ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
Spectral Properties ◽  
Near Infrared ◽  
Molecular Design ◽  
Design Strategies

scholarly journals Site-Specific Labeling of Proteins with Near-IR Heptamethine Cyanine Dyes

Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 2900 ◽  
Author(s):  
Chen-Ming Lin ◽  
Syed Usama ◽  
Kevin Burgess
Keyword(s):  
Amino Acids ◽  
Fluorescent Probes ◽  
Near Infrared ◽  
Cyanine Dyes ◽  
Light Penetration ◽  
Selective Labeling ◽  
Site Specific ◽  
Physiological Conditions ◽  
Near Ir ◽  
Aqueous Environments

Convenient labeling of proteins is important for observing its function under physiological conditions. In tissues particularly, heptamethine cyanine dyes (Cy-7) are valuable because they absorb in the near-infrared (NIR) region (750–900 nm) where light penetration is maximal. In this work, we found Cy-7 dyes with a meso-Cl functionality covalently binding to proteins with free Cys residues under physiological conditions (aqueous environments, at near neutral pH, and 37 °C). It transpired that the meso-Cl of the dye was displaced by free thiols in protein, while nucleophilic side-chains from amino acids like Tyr, Lys, and Ser did not react. This finding shows a new possibility for convenient and selective labeling of proteins with NIR fluorescent probes.

Water-soluble near-infrared fluorescent probes enhanced by ionic co-assembly of a four-armed amphiphile with SDBS: Toward application in cell imaging

2020 ◽  
Vol 181 ◽  
pp. 108541
Author(s):  
Lina Zhang ◽  
Shixin Zhou ◽  
Shenxi Min ◽  
Xiaobo Yu ◽  
Guangliang Hou ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
Near Infrared ◽  
Cell Imaging ◽  
Water Soluble
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