Amino acid sequence of amyloid-related apoprotein (apoSAA1) from human high-density lipoprotein

Biochemistry ◽  
1982 ◽  
Vol 21 (14) ◽  
pp. 3298-3303 ◽  
Author(s):  
David C. Parmelee ◽  
Koiti Titani ◽  
Lowell H. Ericsson ◽  
Nils Eriksen ◽  
Earl P. Benditt ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
High Density Lipoprotein ◽  
Density Lipoprotein ◽  
High Density ◽  
Human High Density Lipoprotein

scholarly journals Amino Acid Sequence of Human apoLp-Gln-II (apoA-II), an Apolipoprotein Isolated from the High-Density Lipoprotein Complex

1972 ◽  
Vol 69 (5) ◽  
pp. 1304-1308 ◽  
Author(s):  
H. B. Brewer ◽  
S. E. Lux ◽  
R. Ronan ◽  
K. M. John
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
High Density Lipoprotein ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Complex

scholarly journals The Specific Amino Acid Sequence between Helices 7 and 8 Influences the Binding Specificity of Human Apolipoprotein A-I for High Density Lipoprotein (HDL) Subclasses

2008 ◽  
Vol 283 (23) ◽  
pp. 15779-15788 ◽  
Author(s):  
Ronald Carnemolla ◽  
Xuefeng Ren ◽  
Tapan K. Biswas ◽  
Stephen C. Meredith ◽  
Catherine A. Reardon ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
High Density Lipoprotein ◽  
Density Lipoprotein ◽  
Binding Specificity ◽  
High Density ◽  
Specific Amino Acid ◽  
Human Apolipoprotein ◽  
Apolipoprotein A

scholarly journals The interaction of apoA-I from human high density lipoprotein with lysolecithin.

1975 ◽  
Vol 250 (18) ◽  
pp. 7300-7306 ◽  
Author(s):  
J Gwynne ◽  
G Palumbo ◽  
H B Brewer ◽  
H Edelhoch
Keyword(s):  
High Density Lipoprotein ◽  
Density Lipoprotein ◽  
High Density ◽  
Human High Density Lipoprotein

scholarly journals Serum amyloid A-containing human high density lipoprotein 3. Density, size, and apolipoprotein composition.

1986 ◽  
Vol 261 (21) ◽  
pp. 9644-9651 ◽  
Author(s):  
G A Coetzee ◽  
A F Strachan ◽  
D R van der Westhuyzen ◽  
H C Hoppe ◽  
M S Jeenah ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Serum Amyloid A ◽  
Density Lipoprotein ◽  
High Density ◽  
Serum Amyloid ◽  
Amyloid A ◽  
Human High Density Lipoprotein

scholarly journals Binding of high density lipoprotein to cultured fibroblasts after chemical alteration of apoprotein amino acid residues.

1986 ◽  
Vol 261 (1) ◽  
pp. 495-503 ◽  
Author(s):  
E A Brinton ◽  
J F Oram ◽  
C H Chen ◽  
J J Albers ◽  
E L Bierman
Keyword(s):  
Amino Acid ◽  
High Density Lipoprotein ◽  
Density Lipoprotein ◽  
High Density ◽  
Amino Acid Residues ◽  
Cultured Fibroblasts ◽  
Chemical Alteration

Effect of polyenephosphatidylcholine on cholesterol uptake by human high density lipoprotein

1981 ◽  
Vol 39 (4) ◽  
pp. 527-542 ◽  
Author(s):  
O. Zierenberg ◽  
G. Assmann ◽  
G. Schmitz ◽  
M. Rosseneu
Keyword(s):  
High Density Lipoprotein ◽  
Density Lipoprotein ◽  
High Density ◽  
Cholesterol Uptake ◽  
Human High Density Lipoprotein

scholarly journals In Vitro Generation of Human High-Density-Lipoprotein-Resistant Trypanosoma brucei brucei

2006 ◽  
Vol 5 (8) ◽  
pp. 1276-1286 ◽  
Author(s):  
Sara D. Faulkner ◽  
Monika W. Oli ◽  
Rudo Kieft ◽  
Laura Cotlin ◽  
Justin Widener ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Trypanosoma Brucei ◽  
Density Lipoprotein ◽  
High Density ◽  
Surface Glycoprotein ◽  
Trypanosoma Brucei Brucei ◽  
African Trypanosomes ◽  
Expression Site ◽  
Human High Density Lipoprotein

ABSTRACT The host range of African trypanosomes is influenced by innate protective molecules in the blood of primates. A subfraction of human high-density lipoprotein (HDL) containing apolipoprotein A-I, apolipoprotein L-I, and haptoglobin-related protein is toxic to Trypanosoma brucei brucei but not the human sleeping sickness parasite Trypanosoma brucei rhodesiense. It is thought that T. b. rhodesiense evolved from a T. b. brucei-like ancestor and expresses a defense protein that ablates the antitrypanosomal activity of human HDL. To directly investigate this possibility, we developed an in vitro selection to generate human HDL-resistant T. b. brucei. Here we show that conversion of T. b. brucei from human HDL sensitive to resistant correlates with changes in the expression of the variant surface glycoprotein (VSG) and abolished uptake of the cytotoxic human HDLs. Complete transcriptome analysis of the HDL-susceptible and -resistant trypanosomes confirmed that VSG switching had occurred but failed to reveal the expression of other genes specifically associated with human HDL resistance, including the serum resistance-associated gene (SRA) of T. b. rhodesiense. In addition, we found that while the original active expression site was still utilized, expression of three expression site-associated genes (ESAG) was altered in the HDL-resistant trypanosomes. These findings demonstrate that resistance to human HDLs can be acquired by T. b. brucei.

Characteristics of Six Fractions Obtained from Human High Density Lipoprotein

1972 ◽  
pp. 41-45
Author(s):  
GERMáN CAMEJO ◽  
VICTOR MUñOZ ◽  
ELBA AVILA
Keyword(s):  
High Density Lipoprotein ◽  
Density Lipoprotein ◽  
High Density ◽  
Human High Density Lipoprotein
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