Disulfide bond formation between the active-site thiol and one of the several free thiol groups of chymopapain

Biochemistry ◽  
1986 ◽  
Vol 25 (22) ◽  
pp. 6895-6900 ◽  
Author(s):  
Ibolya Korodi ◽  
Bence Asboth ◽  
Laszlo Polgar
Keyword(s):  
Disulfide Bond ◽  
Active Site ◽  
Bond Formation ◽  
Disulfide Bond Formation ◽  
Thiol Groups ◽  
Free Thiol

scholarly journals Free thiol groups are essential for infectivity of human cytomegalovirus

1999 ◽  
Vol 80 (11) ◽  
pp. 2861-2865 ◽  
Author(s):  
Ali Mirazimi ◽  
Mehrdad Mousavi-Jazi ◽  
Vivi-Anne Sundqvist ◽  
Lennart Svensson
Keyword(s):  
Human Cytomegalovirus ◽  
Disulfide Bond ◽  
Virus Entry ◽  
Bond Formation ◽  
Reducing Agent ◽  
Disulfide Bond Formation ◽  
Thiol Groups ◽  
Nitrobenzoic Acid ◽  
Free Thiol

The membrane-impermeable thiol blocker 5′5-dithiobis 2- nitrobenzoic acid (DTNB) blocked infectivity of human cytomegalovirus (CMV) although the virus still bound to cells. DTNB-treated CMV regained 65% of its infectivity after incubation with the disulfide bond-reducing agent dithiothreitol. These observations suggest that free thiol groups on CMV are required for infectivity and may participate in disulfide bond formation during virus entry.

scholarly journals Oxygen-independent disulfide bond formation in VEGF-A and CA9

2021 ◽  
pp. 100505
Author(s):  
Fiana Levitin ◽  
Sandy Che-Eun Serena Lee ◽  
Stephanie Hulme ◽  
Ryan A. Rumantir ◽  
Amy S. Wong ◽  
...  
Keyword(s):  
Disulfide Bond ◽  
Bond Formation ◽  
Disulfide Bond Formation
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