An Intersubunit Disulfide Bond Prevents in Vitro Aggregation of a Superoxide Dismutase-1 Mutant Linked to Familial Amytrophic Lateral Sclerosis†

50bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis

10.1080/17482960802103107 ◽

2008 ◽

Vol 9 (4) ◽

pp. 229-237 ◽

Cited By ~ 19

Author(s):

Wendy J. Broom ◽

Matthew Greenway ◽

Ghazaleh Sadri-Vakili ◽

Carsten Russ ◽

Kristen E. Auwarter ◽

...

Keyword(s):

Superoxide Dismutase ◽

Age Of Onset ◽

Sporadic Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase 1 ◽

Transgenic mouse model for familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation

Neuropathology ◽

10.1046/j.1440-1789.2001.00361.x ◽

2001 ◽

Vol 21 (1) ◽

pp. 82-92 ◽

Cited By ~ 72

Author(s):

Noriyuki Shibata

Keyword(s):

Superoxide Dismutase ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Familial Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase 1 ◽

Glial nuclear aggregates of superoxide dismutase-1 are regularly present in patients with amyotrophic lateral sclerosis

Acta Neuropathologica ◽

10.1007/s00401-011-0805-3 ◽

2011 ◽

Vol 121 (5) ◽

pp. 623-634 ◽

Cited By ~ 101

Author(s):

Karin Forsberg ◽

Peter M. Andersen ◽

Stefan L. Marklund ◽

Thomas Brännström

Keyword(s):

Superoxide Dismutase ◽

Superoxide Dismutase 1 ◽

Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.94.14.7606 ◽

1997 ◽

Vol 94 (14) ◽

pp. 7606-7611 ◽

Cited By ~ 200

Author(s):

L. I. Bruijn ◽

M. F. Beal ◽

M. W. Becher ◽

J. B. Schulz ◽

P. C. Wong ◽

...

Keyword(s):

Superoxide Dismutase ◽

Hydroxyl Radicals ◽

Tyrosine Nitration ◽

Superoxide Dismutase 1 ◽

Familial Als ◽

Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells

Journal of Neurochemistry ◽

10.1111/j.1471-4159.2007.05053.x ◽

2008 ◽

Vol 104 (4) ◽

pp. 993-1005 ◽

Cited By ~ 51

Author(s):

Yeo Kyoung Oh ◽

Ki Soon Shin ◽

Junying Yuan ◽

Shin Jung Kang

Keyword(s):

Superoxide Dismutase ◽

Superoxide Dismutase 1 ◽

Neuro2a Cells ◽

Conjugates of Superoxide Dismutase 1 with Amphiphilic Poly(2-oxazoline) Block Copolymers for Enhanced Brain Delivery: Synthesis, Characterization and Evaluation in Vitro and in Vivo

Molecular Pharmaceutics ◽

10.1021/mp300496x ◽

2012 ◽

Vol 10 (1) ◽

pp. 360-377 ◽

Cited By ~ 53

Author(s):

Jing Tong ◽

Xiang Yi ◽

Robert Luxenhofer ◽

William A. Banks ◽

Rainer Jordan ◽

...

Keyword(s):

Superoxide Dismutase ◽

Block Copolymers ◽

Brain Delivery ◽

Superoxide Dismutase 1

New consensus research on neuropathological aspects of familial amyotrophic lateral sclerosis with superoxide dismutase 1 (SOD1) gene mutations: Inclusions containing SOD1 in neurons and astrocytes

Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders ◽

10.1080/14660820050515160 ◽

2000 ◽

Vol 1 (3) ◽

pp. 163-184 ◽

Cited By ~ 106

Author(s):

Shinsuke Kato ◽

Miki Takikawa ◽

Kenji Nakashima ◽

Asao Hirano ◽

Don W Cleveland ◽

...

Keyword(s):

Superoxide Dismutase ◽

Gene Mutations ◽

Familial Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase 1 ◽

Sod1 Gene ◽

Impaired Fertilizing Ability of Superoxide Dismutase 1-Deficient Mouse Sperm During In Vitro Fertilization1

Biology of Reproduction ◽

10.1095/biolreprod.112.102129 ◽

2012 ◽

Vol 87 (5) ◽

Cited By ~ 26

Author(s):

Satoshi Tsunoda ◽

Natsuko Kawano ◽

Kenji Miyado ◽

Naoko Kimura ◽

Junichi Fujii

Keyword(s):

Superoxide Dismutase ◽

Deficient Mouse ◽

Superoxide Dismutase 1 ◽

Mouse Sperm ◽

Fertilizing Ability

Neuropathology of familial amyotrophic lateral sclerosis patients with superoxide dismutase 1 gene mutation

Neuropathology ◽

10.1111/j.1440-1789.1998.tb00132.x ◽

1998 ◽

Vol 18 (4) ◽

pp. 363-369 ◽

Cited By ~ 14

Author(s):

Asao Hirano

Keyword(s):

Superoxide Dismutase ◽

Gene Mutation ◽

Familial Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase 1 ◽

Phenotype of Transgenic Mice Carrying a Very Low Copy Number of the Mutant Human G93A Superoxide Dismutase-1 Gene Associated with Amyotrophic Lateral Sclerosis

PLoS ONE ◽

10.1371/journal.pone.0099879 ◽

2014 ◽

Vol 9 (6) ◽

pp. e99879 ◽

Cited By ~ 8

Author(s):

Jeffrey S. Deitch ◽

Guillermo M. Alexander ◽

Andrew Bensinger ◽

Steven Yang ◽

Juliann T. Jiang ◽

...

Keyword(s):

Superoxide Dismutase ◽

Transgenic Mice ◽

Copy Number ◽

Superoxide Dismutase 1 ◽

Low Copy Number ◽