Effects of Bulkiness and Hydrophobicity of an Aliphatic Amino Acid in the Recognition Helix of the GAGA Zinc Finger on the Stability of the Hydrophobic Core and DNA Binding Affinity†

Biochemistry ◽  
2008 ◽  
Vol 47 (45) ◽  
pp. 11717-11724 ◽  
Author(s):  
Muthu Dhanasekaran ◽  
Shigeru Negi ◽  
Miki Imanishi ◽  
Michiko Suzuki ◽  
Yukio Sugiura
Keyword(s):  
Amino Acid ◽  
Dna Binding ◽  
Binding Affinity ◽  
Zinc Finger ◽  
Hydrophobic Core ◽  
Aliphatic Amino Acid ◽  
Dna Binding Affinity ◽  
Recognition Helix ◽  
The Stability

scholarly journals C-terminal in Sp1-like artificial zinc-finger proteins plays crucial roles in determining their DNA binding affinity

2013 ◽  
Vol 13 (1) ◽  
pp. 106 ◽  
Author(s):  
Baozhen Zhang ◽  
Shengyan Xiang ◽  
Yanru Yin ◽  
Liankun Gu ◽  
Dajun Deng
Keyword(s):  
Dna Binding ◽  
Binding Affinity ◽  
Zinc Finger ◽  
Zinc Finger Proteins ◽  
Dna Binding Affinity

Multiconnection of Identical Zinc Finger: Implication for DNA Binding Affinity and Unit Modulation of the Three Zinc Finger Domain†

Biochemistry ◽  
2001 ◽  
Vol 40 (9) ◽  
pp. 2932-2941 ◽  
Author(s):  
Makoto Nagaoka ◽  
Tamaki Kaji ◽  
Miki Imanishi ◽  
Yuichiro Hori ◽  
Wataru Nomura ◽  
...  
Keyword(s):  
Dna Binding ◽  
Binding Affinity ◽  
Zinc Finger ◽  
Zinc Finger Domain ◽  
Dna Binding Affinity

A SALL4 zinc finger missense mutation predicted to result in increased DNA binding affinity is associated with cranial midline defects and mild features of Okihiro syndrome

2006 ◽  
Vol 119 (1-2) ◽  
pp. 154-161 ◽  
Author(s):  
Jan Miertus ◽  
Wiktor Borozdin ◽  
Vladimir Frecer ◽  
Giorgio Tonini ◽  
Sara Bertok ◽  
...  
Keyword(s):  
Dna Binding ◽  
Missense Mutation ◽  
Binding Affinity ◽  
Zinc Finger ◽  
Midline Defects ◽  
Dna Binding Affinity
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