Fatty Acids and Fungal Development: Structure-Activity Relationships

1987 ◽  
pp. 329-342 ◽  
Author(s):  
James L. Kerwin
Keyword(s):  
Fatty Acids ◽  
Fungal Development ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Development Structure

Novel Antimicrobial 8-Hydroxyquinoline-Based Agents: Current Development, Structure–Activity Relationships, and Perspectives

2021 ◽  
Author(s):  
Angélica Rocha Joaquim ◽  
Mariana Pies Gionbelli ◽  
Grace Gosmann ◽  
Alexandre Meneghello Fuentefria ◽  
Marcela Silva Lopes ◽  
...  
Keyword(s):  
Current Development ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Development Structure

Synthesis and Cytotoxic Activities of New Fatty Acid Esters of 20(S)-Protopanaxadiol

2011 ◽  
Vol 66 (5-6) ◽  
pp. 199-204 ◽  
Author(s):  
Ning Li ◽  
Yuan Huang ◽  
Wan Xiao ◽  
Xian Li ◽  
Pingya Li ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Fatty Acid Esters ◽  
Cytotoxic Activities ◽  
Structure Activity Relationships ◽  
Lead Compounds ◽  
Structure Activity ◽  
Diphenyltetrazolium Bromide ◽  
Oleoyl Chloride ◽  
Acid Esters

In order to find new lead compounds with antitumour activies, thirteen new fatty acid esters of 20(S)-protopanaxadiol (PPD) were synthesized using oleoyl chloride or fatty acids and N,N’-dicyclohexylcarbodiimide (DCC). Their cytotoxic activities were tested using the MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] method, and the structure- activity relationships between the fatty acid esters of PPD and their cytotoxic activities are discussed.

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