Integrating Medicinal Chemistry, Organic/Combinatorial Chemistry, and Computational Chemistry for the Discovery of Selective Estrogen Receptor Modulators with Forecaster, a Novel Platform for Drug Discovery

Chemocentric Informatics Approach to Drug Discovery: Identification and Experimental Validation of Selective Estrogen Receptor Modulators as Ligands of 5-Hydroxytryptamine-6 Receptors and as Potential Cognition Enhancers

Journal of Medicinal Chemistry ◽

10.1021/jm2011657 ◽

2012 ◽

Vol 55 (12) ◽

pp. 5704-5719 ◽

Cited By ~ 26

Author(s):

Rima Hajjo ◽

Vincent Setola ◽

Bryan L. Roth ◽

Alexander Tropsha

Keyword(s):

Estrogen Receptor ◽

Drug Discovery ◽

Experimental Validation ◽

Medicinal Chemistry and Emerging Strategies Applied to the Development of Selective Estrogen Receptor Modulators (SERMs)

Current Medicinal Chemistry ◽

10.2174/092986707780598023 ◽

2007 ◽

Vol 14 (11) ◽

pp. 1249-1261 ◽

Cited By ~ 43

Author(s):

Musiliyu Musa ◽

M. Omar F. Khan ◽

John Cooperwood

Keyword(s):

Estrogen Receptor ◽

Medicinal Chemistry ◽

A review of selective estrogen receptor modulators in the treatment of breast and endometrial cancer

Seminars in Oncology ◽

10.1053/sonc.2002.34065 ◽

2002 ◽

Vol 29 (3 Suppl 11) ◽

pp. 129-133 ◽

Cited By ~ 27

Author(s):

Stephen Chan

Keyword(s):

Estrogen Receptor ◽

Endometrial Cancer ◽

Faculty Opinions recommendation of FDA-approved selective estrogen receptor modulators inhibit Ebola virus infection.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718030692.793484645 ◽

2013 ◽

Author(s):

Anne Moscona ◽

Laura M Palermo ◽

Matteo Porotto

Keyword(s):

Estrogen Receptor ◽

Virus Infection ◽

Ebola Virus ◽

Receptor Modulators ◽

Ebola Virus Infection

Definition of the Molecular Mechanisms Which Distinguish Between Selective Estrogen Receptor Modulators (SERMs) and Full Antiestrogens

10.21236/ada426883 ◽

2004 ◽

Author(s):

Huey-Jing Huang

Keyword(s):

Estrogen Receptor ◽

Molecular Mechanisms ◽

Definition Of ◽

Definition of the Molecular Mechanisms Which Distinguish Between Selective Estrogen Receptor Modulators (SERMs) and Full Antiestrogens

10.21236/ada436900 ◽

2005 ◽

Author(s):

Huey-Jing Huang

Keyword(s):

Estrogen Receptor ◽

Molecular Mechanisms ◽

Definition Of ◽

Can biomarkers direct the optimal use of aromatase inhibitors versus selective estrogen receptor modulators?

Nature Clinical Practice Oncology ◽

10.1038/ncponc0444 ◽

2006 ◽

Vol 3 (3) ◽

pp. 134-135

Author(s):

Rachel Schiff ◽

Adrian V Lee

Keyword(s):

Estrogen Receptor ◽

Aromatase Inhibitors ◽

A Novel Strategy to Improve Women’s Health: Selective Estrogen Receptor Modulators

Estrogen Receptor and Breast Cancer - Cancer Drug Discovery and Development ◽

10.1007/978-3-319-99350-8_8 ◽

2018 ◽

pp. 189-213 ◽

Cited By ~ 2

Author(s):

Balkees Abderrahman ◽

V. Craig Jordan

Keyword(s):

Estrogen Receptor ◽

Women’S Health ◽

Women's Health ◽

Novel Strategy ◽

Selective estrogen receptor modulators prevent neointima formation after vascular injury

Molecular and Cellular Endocrinology ◽

10.1016/j.mce.2004.08.004 ◽

2004 ◽

Vol 227 (1-2) ◽

pp. 9-20 ◽

Cited By ~ 12

Author(s):

Hanna Savolainen-Peltonen ◽

Nina-Maria Luoto ◽

Lauri Kangas ◽

Pekka Häyry

Keyword(s):

Estrogen Receptor ◽

Vascular Injury ◽

Neointima Formation ◽

Current Status of Selective Estrogen Receptor Modulators (SERMs)

The Cancer Journal ◽

10.1097/00130404-200301000-00003 ◽

2003 ◽

Vol 9 (1) ◽

pp. 4-14 ◽

Cited By ~ 5

Author(s):

Suzanne D. Conzen

Keyword(s):

Estrogen Receptor ◽

Current Status ◽