A Sol−Gel Method Using Tetraethoxysilane and Acetic Anhydride:  Immobilization of Cubic μ-Oxo Si−Ti Complex in a Silica Matrix

ABSTRACTWe describe the use of immobilized deoxyribonucleic acid (DNA) in a silica matrix as a biorecognition agent for the detection of albendazole sulfoxide (ASU), the primary metabolite of albendazole and a suspected teratogenic and embryotoxic agent. The biomaterial (DNA-containing gel) was synthesized by physical entrapment of salmon sperm in an inorganic silicate matrix by the sol-gel method. Functionality of the DNA-containing gel was evaluated by comparative offline frontal chromatography followed by HPLC analysis of ASU and caffeine (CAF, control) using DNA-containing gel and DNA-free gel. The DNA-containing gel showed relatively high specific retention for ASU, while CAF showed no retention using frontal analysis. We anticipate that the DNA-containing gel can be implemented to identify the interactions of DNA with other active pharmaceutical ingredients (APIs) and their metabolites in a readily available, sensitive and selective frontal chromatography experiment.

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Luminescence properties of the ternary rare earth complexes with β-diketones and 1,10-phenanthroline incorporated in silica matrix by a sol-gel method

Materials Chemistry and Physics ◽

10.1016/s0254-0584(97)80274-x ◽

1997 ◽

Vol 51 (1) ◽

pp. 92-96 ◽

Cited By ~ 65

Author(s):

Bing Yan ◽

Hong-jie Zhang ◽

Shu-bin Wang ◽

Jia-zuan Ni

Keyword(s):

Rare Earth ◽

Sol Gel ◽

Silica Matrix ◽

Rare Earth Complexes ◽

Luminescence Properties ◽

Gel Method ◽

Sol Gel Method

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Iron and Iron-oxide on Silica Nanocomposites Prepared by the Sol-gel Method

Journal of Materials Research ◽

10.1557/jmr.2002.0083 ◽

2002 ◽

Vol 17 (3) ◽

pp. 590-596 ◽

Cited By ~ 15

Author(s):

G. Ennas ◽

M. F. Casula ◽

G. Piccaluga ◽

S. Solinas ◽

M. P. Morales ◽

...

Keyword(s):

Sol Gel ◽

Silica Matrix ◽

Molar Ratio ◽

X Ray Diffraction ◽

Scanning Calorimetry ◽

Gel Method ◽

Sol Gel Method ◽

Silica Nanocomposites ◽

Transmission Electron ◽

Nanometric Particles

γ–Fe2O3/SiO2 and Fe/SiO2 nanocomposites, with a Fe/Si molar ratio of 0.25, were prepared by the sol-gel method starting from ethanolic solutions of tetraethoxysilane and iron (III) nitrate. After gelation the xerogels were oxidated or reduced. Samples were investigated by transmission electron microscopy, x-ray diffraction, differential scanning calorimetry, and thermogravimetry. Magnetic properties of the samples were investigated at room temperature (RT) and at 77 K. Nanometric particles supported in the silica matrix were obtained in all cases. Bigger particles (10 nm) were obtained in the case of Fe/SiO2 nanocomposites with respect to the γ–Fe2O3/SiO2 samples (5–8 nm). A slight effect of sol dilution on particle size was observed only in the case of γ–Fe2O3/SiO2 nanocomposites. A superparamagnetic behavior was shown at RT only by γ–Fe2O3/SiO2 nanocomposites. Iron-based composites exhibited coercivity values higher than 700 Oe at RT.

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Luminescence and thermal stability of sodium tris(pyridine dicarboxylate) terbate(III) complex incorporated in silica matrix by sol-gel method

Materials Research Bulletin ◽

10.1016/s0025-5408(01)00618-3 ◽

2001 ◽

Vol 36 (7-8) ◽

pp. 1335-1346 ◽

Cited By ~ 10

Author(s):

Bao-li An ◽

Jian-qing Ye ◽

Meng-lian Gong ◽

Xian-hong Yin ◽

Yan-sheng Yang ◽

...

Keyword(s):

Thermal Stability ◽

Sol Gel ◽

Silica Matrix ◽

Gel Method ◽

Sol Gel Method ◽

Thermal Stability Of

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Preparation and luminescence properties of the europium complex with α-naphthylacetic acid and 1,10-phenanthroline incorporated in silica matrix by sol–gel method

Materials Chemistry and Physics ◽

10.1016/s0254-0584(02)00541-2 ◽

2003 ◽

Vol 80 (1) ◽

pp. 371-375 ◽

Cited By ~ 2

Author(s):

Chen Ye ◽

Sun Xiao Jun ◽

Cai Wei Min ◽

Yu Ying Ning ◽

Cui Dan

Keyword(s):

Sol Gel ◽

Silica Matrix ◽

Europium Complex ◽

Luminescence Properties ◽

Gel Method ◽

Sol Gel Method ◽

Naphthylacetic Acid

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Eu3+-Doped Y2O3-SiO2 Nanocomposite Obtained by a Sol-Gel Method

MRS Proceedings ◽

10.1557/proc-676-y3.18 ◽

2001 ◽

Vol 676 ◽

Cited By ~ 7

Author(s):

Carla Cannas ◽

Mariano Casu ◽

Roberta Licheri ◽

Anna Musinu ◽

Giorgio Piccaluga ◽

...

Keyword(s):

Amorphous Silica ◽

Sol Gel ◽

Silica Matrix ◽

Luminescence Spectroscopy ◽

X Ray Diffraction ◽

Gel Method ◽

X Ray ◽

Sol Gel Method ◽

Excited Luminescence ◽

The Eu

ABSTRACTA Y2O3-SiO2 nanocomposite doped with Eu3+ was obtained by a sol-gel method and characterized by X-ray diffraction, IR, 29Si NMR and laser-excited luminescence spectroscopy. It was found that small (2-3 nm) yttria nanoparticles are homogeneously dispersed in, and interacting with, the amorphous silica matrix. Luminescence spectroscopy indicates that the Eu3+ ion is preferentially located inside or at the surface of highly disordered Y2O3 nanoparticles. These luminescent nanocomposites form a class of materials which could find applications in the field of phosphors.

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