Reactions of functional groups: An approach for the basic course in organic chemistry

1962 ◽  
Vol 39 (6) ◽  
pp. 303
Author(s):  
Ludwig Bauer ◽  
Ralph Daniels
Keyword(s):  
Organic Chemistry ◽  
Functional Groups ◽  
Basic Course

ORGANIC CHEMISTRY: FUNCTIONAL GROUPS AND THE MOLECULES OF BIOCHEMISTRY

Chemistry ◽  
1980 ◽  
pp. 1009-1042
Author(s):  
Therald Moeller ◽  
John C. Bailar ◽  
Jacob Kleinberg ◽  
Cyrus O. Guss ◽  
Mary E. Castellion ◽  
...  
Keyword(s):  
Organic Chemistry ◽  
Functional Groups

scholarly journals Study of Effectiveness of Pattern Based Teaching Method on Students’ Long-Term Retention of Contents in Organic Chemistry

2021 ◽  
Vol 3 (5) ◽  
pp. 26-35
Author(s):  
Chandra Prakash Pokharna ◽  
Neetu Bharatiyaa
Keyword(s):  
Organic Chemistry ◽  
Functional Groups ◽  
Systematic Approach ◽  
Teaching Method ◽  
Control Groups ◽  
Traditional Lecture ◽  
Term Retention ◽  
The Subject ◽  
Long Term Retention

Organic chemistry is a subject which students find difficult because of complex reactions and mechanisms involved. The main aim of this study was to study the students' understanding of the concepts of organic chemistry by pattern based teaching method (PBT). Pattern Based Teaching is a systematic approach in teaching chemistry where the reactions and mechanisms are systematized into a particular pattern for different functional groups. The students are made to understand the basic concepts how to introduce a particular functional group and how functional groups give reactions with different type of reagents. The present paper reports the effect of this innovative teaching method on students' long term retention of organic chemistry course material. Long term retention of contents was examined by conducting two tests-pretest (based on traditional lecture teaching) and a post-test (conducted after PBT). Students' of first year undergraduate class of two different colleges of Kishangarh city of Ajmer district of Rajasthan were used for the study. These students were divided into six groups and two of them were taught by the author by PBT method. The rest four groups were control groups taught by the traditional lecture based teaching method. Students performance after PBT method was compared to that in a traditional lecture based teaching method. Our analysis showed that the out of the six sample groups of students used in our study, the highest mean scores (10.46 and 13.36) were of the two experimental groups. The four control groups had mean scores in the range 7-10. This investigation thus suggests that pattern-based teaching in organic chemistry is a powerful and systematic approach which facilitates students’ long-term retention of contents of the subject. It promotes active learning and creates students’ interest in the subject.

scholarly journals Synthetic exploration of sulfinyl radicals using sulfinyl sulfones

2021 ◽  
Author(s):  
Zikun Wang ◽  
Zhansong Zhang ◽  
Wanjun Zhao ◽  
Paramasivam Sivaguru ◽  
Zanoni Giuseppe ◽  
...  
Keyword(s):  
Organic Chemistry ◽  
Functional Groups ◽  
Radical Addition ◽  
Single Step ◽  
Unsaturated Hydrocarbons ◽  
Radical Coupling ◽  
Extensive Range ◽  
Mechanistic Investigations ◽  
Sulfinyl Radical ◽  
Synthetic Application

Abstract Sulfinyl radicals – one of the fundamental classes of S-centered radicals – have eluded synthetic application in organic chemistry for over 60 years, despite their potential to assemble valuable sulfoxide compounds. Here we report the successful generation and use of sulfinyl radicals in a dual radical addition / radical coupling with unsaturated hydrocarbons, where readily-accessed sulfinyl sulfones serve as the sulfinyl radical precursor. The strategy provides an entry to a variety of previously inaccessible linear and cyclic disulfurized adducts in a single step, and demonstrates excellent tolerance to an extensive range of hydrocarbons and functional groups. Experimental and theoretical mechanistic investigations suggest that these reactions proceed through sequential sulfonyl and sulfinyl radical addition.

scholarly journals Nickel-Catalyzed Site- and Stereoselective Reductive Alkylalkynylation of Alkynes

2020 ◽  
Author(s):  
Yi Jiang ◽  
Jiaoting Pan ◽  
Tao Yang ◽  
Joel Jun Han Lim ◽  
Yu Zhao ◽  
...  
Keyword(s):  
Organic Chemistry ◽  
Functional Groups ◽  
Multicomponent Reaction ◽  
Alkyl Group ◽  
Crucial Role ◽  
Building Blocks ◽  
Radical Addition ◽  
Active Esters ◽  
Redox Active

Development of a catalytic multicomponent reaction by orthogonal activation of readily available substrates for the streamlined difunctionalization of alkynes is a compelling objective in organic chemistry. Alkyne carboalkynylation, in particular, offers a direct entry to valuable 1,3-enynes with different substitution patterns. Here, we show that the synthesis of stereodefined 1,3-enynes featuring a trisubstituted olefin is achieved by merging alkynes, alkynyl bromides and redox-active <i>N</i>-(acyloxy)phthalimides through nickel-catalyzed reductive alkylalkynylation. Products are generated in up to 89% yield as single regio- and <i>E</i> isomers. Transformations are tolerant of diverse functional groups and the resulting 1,3-enynes are amenable to further elaboration to synthetically useful building blocks. With olefin-tethered <i>N</i>-(acyloxy)phthalimides, a cascade radical addition/cyclization/alkynylation process can be implemented to obtain 1,5-enynes. The present study underscores the crucial role of redox-active esters as superior alkyl group donors compared to haloalkanes in reductive alkyne dicarbofunctionalizations.

scholarly journals One pot conversion of benzophenone imine into the relevant 2-aza-allenium

2017 ◽  
Vol 53 (2) ◽  
pp. 364-367 ◽  
Author(s):  
Marco Bortoluzzi ◽  
Tiziana Funaioli ◽  
Fabio Marchetti ◽  
Guido Pampaloni ◽  
Calogero Pinzino ◽  
...  
Keyword(s):  
Organic Chemistry ◽  
Functional Groups ◽  
One Pot ◽  
New Feature

WCl6-mediated partial conversion of benzophenone imine into tetraphenyl-2-aza-allenium,viaN2elimination and intermolecular CN fusion, provides a new feature in the chemistry of one of the most strategic functional groups in organic chemistry.

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