In the present paper the segregating behaviour of solids of different size and density in gas-fluidized beds is studied. In particular, the attention is focussed on pairs composed of a bigger/less dense species and a smaller/denser species. Typical industrial examples of such combinations are encountered in fluidized beds of biomass/sand mixtures. Their behaviour is not easily predictable, as the segregation tendency promoted by the difference in density is counteracted by the difference in size. While typically the denser component is expected to appear predominantly at the bottom of the fluidized bed, experiments on mixtures exhibiting the reverse behaviour have been reported (e.g. Chiba et al., 1980).A simple model to predict the segregation direction of the components, i.e. which species will segregate to the top of the bed (the flotsam), depending upon their difference in properties (size, density) and the mixture composition, is discussed. The predicted behaviour is compared with experimental data available in the literature and agreement is found for the majority of them. For one mixture, experiments are conducted as well as computational simulations based on the combined Discrete Element Method and Computational Fluid Dynamics (DEM-CFD) approach. This allows investigating how an initially mixed bed upon suspension evolves as a result of the segregation prevalence in the bed.