Sequence Selective Hydrolysis of Linear DNA Using Conjugates of Zr(IV) Complexes and Peptide Nucleic Acids

Felix H. Zelder; Andriy A. Mokhir; Roland Krämer

doi:10.1021/ic034896v

Sequence Selective Hydrolysis of Linear DNA Using Conjugates of Zr(IV) Complexes and Peptide Nucleic Acids

Inorganic Chemistry ◽

10.1021/ic034896v ◽

2003 ◽

Vol 42 (26) ◽

pp. 8618-8620 ◽

Cited By ~ 48

Author(s):

Felix H. Zelder ◽

Andriy A. Mokhir ◽

Roland Krämer

Keyword(s):

Nucleic Acids ◽

Peptide Nucleic Acids ◽

Selective Hydrolysis ◽

Linear Dna ◽

Hydrolysis Of

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Faculty Opinions recommendation of Sequence selective hydrolysis of linear DNA using conjugates of Zr(IV) complexes and peptide nucleic acids.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1017407.202865 ◽

2004 ◽

Author(s):

Makoto Komiyama

Keyword(s):

Nucleic Acids ◽

Peptide Nucleic Acids ◽

Selective Hydrolysis ◽

Linear Dna ◽

Hydrolysis Of

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End invasion of peptide nucleic acids (PNAs) with mixed-base composition into linear DNA duplexes

Nucleic Acids Research ◽

10.1093/nar/gki933 ◽

2005 ◽

Vol 33 (19) ◽

pp. 6459-6459 ◽

Cited By ~ 8

Author(s):

I. V. Smolina

Keyword(s):

Nucleic Acids ◽

Base Composition ◽

Peptide Nucleic Acids ◽

Dna Duplexes ◽

Linear Dna

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Nonenzymatic hydrolysis of oligoribonucleotides. V. The elements affecting the process of self-hydrolysis.

Acta Biochimica Polonica ◽

10.18388/abp.1999_4192 ◽

1999 ◽

Vol 46 (1) ◽

pp. 145-153 ◽

Cited By ~ 3

Author(s):

A Bibiłło ◽

K Ziomek ◽

M Figlerowicz ◽

R Kierzek

Keyword(s):

Nucleic Acids ◽

Selective Hydrolysis ◽

Chemical Instability ◽

Phosphodiester Bonds ◽

Hydrolysis Of

Chemical instability of some of the phosphodiester bonds, often observed in large RNAs, visualizes the autocatalytic properties of this class of nucleic acids. Unexpectedly, selective hydrolysis occurs also in short oligoribonucleotides (as short as a tetramer or hexamer). Herein, we describe additional experiments which support the conclusion that the hydrolysis is not due to ribonuclease contamination but is of autocatalytic origin and is related to the sequence and structure of single-stranded oligomers. Moreover, we show that the presence in the reaction mixture of polyamines, such as spermidine, is essential for hydrolysis of oligoribonucleotides.

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End invasion of peptide nucleic acids (PNAs) with mixed-base composition into linear DNA duplexes

Nucleic Acids Research ◽

10.1093/nar/gni151 ◽

2005 ◽

Vol 33 (17) ◽

pp. e146-e146 ◽

Cited By ~ 32

Author(s):

I. V. Smolina

Keyword(s):

Nucleic Acids ◽

Base Composition ◽

Peptide Nucleic Acids ◽

Dna Duplexes ◽

Linear Dna

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Molecular insights on the dynamic stability of peptide nucleic acid functionalized carbon and boron nitride nanotubes

Physical Chemistry Chemical Physics ◽

10.1039/d0cp05759b ◽

2021 ◽

Vol 23 (1) ◽

pp. 219-228

Author(s):

Nabanita Saikia ◽

Mohamed Taha ◽

Ravindra Pandey

Keyword(s):

Nucleic Acid ◽

Boron Nitride ◽

Nucleic Acids ◽

Dynamic Stability ◽

Peptide Nucleic Acid ◽

Rational Design ◽

Peptide Nucleic Acids ◽

Boron Nitride Nanotubes ◽

Molecular Hybrids ◽

Single Wall Nanotubes

The rational design of self-assembled nanobio-molecular hybrids of peptide nucleic acids with single-wall nanotubes rely on understanding how biomolecules recognize and mediate intermolecular interactions with the nanomaterial's surface.

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