Cysteine Cyclic Pyrrole–Imidazole Polyamide for Sequence-Specific Recognition in the DNA Minor Groove

2011 ◽  
Vol 133 (46) ◽  
pp. 18924-18930 ◽  
Author(s):  
Hironobu Morinaga ◽  
Toshikazu Bando ◽  
Toshiki Takagaki ◽  
Makoto Yamamoto ◽  
Kaori Hashiya ◽  
...  
Keyword(s):  
Minor Groove ◽  
Dna Minor Groove ◽  
Specific Recognition

scholarly journals Small Sequence‐Sensitive Compounds for Specific Recognition of the G⋅C Base Pair in DNA Minor Groove

2020 ◽  
Vol 26 (20) ◽  
pp. 4539-4551 ◽  
Author(s):  
Abdelbasset A. Farahat ◽  
Pu Guo ◽  
Hadir Shoeib ◽  
Ananya Paul ◽  
David W. Boykin ◽  
...  
Keyword(s):  
Base Pair ◽  
Minor Groove ◽  
Dna Minor Groove ◽  
Specific Recognition

scholarly journals The Thiophene “Sigma-Hole” as a Concept for Preorganized, Specific Recognition of G⋅C Base Pairs in the DNA Minor Groove

2016 ◽  
Vol 22 (43) ◽  
pp. 15404-15412 ◽  
Author(s):  
Pu Guo ◽  
Ananya Paul ◽  
Arvind Kumar ◽  
Abdelbasset A. Farahat ◽  
Dhiraj Kumar ◽  
...  
Keyword(s):  
Minor Groove ◽  
Base Pairs ◽  
Dna Minor Groove ◽  
Specific Recognition ◽  
Sigma Hole

scholarly journals Sequence-specific recognition of DNA minor groove by an NIR-fluorescence switch-on probe and its potential applications

2015 ◽  
Vol 43 (18) ◽  
pp. 8651-8663 ◽  
Author(s):  
Nagarjun Narayanaswamy ◽  
Shubhajit Das ◽  
Pralok K. Samanta ◽  
Khadija Banu ◽  
Guru Prasad Sharma ◽  
...  
Keyword(s):  
Minor Groove ◽  
Dna Minor Groove ◽  
Specific Recognition ◽  
Nir Fluorescence ◽  
Fluorescence Switch ◽  
Potential Applications

scholarly journals Extending the σ-Hole Motif for Sequence-Specific Recognition of the DNA Minor Groove

Biochemistry ◽  
2020 ◽  
Vol 59 (18) ◽  
pp. 1756-1768
Author(s):  
Pu Guo ◽  
Abdelbasset A. Farahat ◽  
Ananya Paul ◽  
Arvind Kumar ◽  
David W. Boykin ◽  
...  
Keyword(s):  
Minor Groove ◽  
Dna Minor Groove ◽  
Specific Recognition

scholarly journals Engineered Modular Heterocyclic-Diamidines for Sequence-Specific Recognition of Mixed AT/GC Base Pairs at the DNA Minor Groove

2021 ◽  
Author(s):  
Pu Guo ◽  
Abdelbasset A. Farahat ◽  
Ananya Paul ◽  
David W Boykin ◽  
W. David Wilson
Keyword(s):  
Minor Groove ◽  
Synthetic Chemistry ◽  
Base Pairs ◽  
Dna Minor Groove ◽  
Specific Recognition ◽  
Minor Groove Binders ◽  
Groove Binders

This report describes a breakthrough in a project to design minor groove binders to recognize any sequence of DNA. A key goal is to invent synthetic chemistry for compound preparation...

scholarly journals Small molecule binders recognize DNA microstructural variations via an induced fit mechanism

2019 ◽  
Vol 21 (4) ◽  
pp. 1841-1851 ◽  
Author(s):  
E. Kathleen Carter ◽  
Sarah Laughlin-Toth ◽  
Thomas Dodd ◽  
W. David Wilson ◽  
Ivaylo Ivanov
Keyword(s):  
Small Molecule ◽  
Minor Groove ◽  
Water Displacement ◽  
Induced Fit ◽  
Site Specific ◽  
Dna Minor Groove ◽  
Specific Recognition

Site-specific recognition through contacts, water displacement, and dynamics of a linked azabenzimidazole-diamidine within the DNA minor groove.

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