Millisecond Time-Resolved Solid-State NMR Reveals a Two-Stage Molecular Mechanism for Formation of Complexes between Calmodulin and a Target Peptide from Myosin Light Chain Kinase

Journal of the American Chemical Society ◽

10.1021/jacs.0c11156 ◽

2020 ◽

Vol 142 (50) ◽

pp. 21220-21232

Author(s):

Jaekyun Jeon ◽

Wai-Ming Yau ◽

Robert Tycko

Keyword(s):

Solid State ◽

Molecular Mechanism ◽

Light Chain ◽

Solid State Nmr ◽

Myosin Light Chain Kinase ◽

Myosin Light Chain ◽

Two Stage ◽

Time Resolved ◽

Target Peptide ◽

Formation Of Complexes

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Structure and Function of Myosin Light Chain Kinase of Smooth Muscle: N-Terminal Actin-Binding Domain.

The Kitakanto Medical Journal ◽

10.2974/kmj.47.57 ◽

1997 ◽

Vol 47 (2) ◽

pp. 57-65

Author(s):

Li-Hong Ye

Keyword(s):

Smooth Muscle ◽

Light Chain ◽

Myosin Light Chain Kinase ◽

Myosin Light Chain ◽

Structure And Function ◽

Binding Domain ◽

Actin Binding ◽

Actin Binding Domain ◽

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Faculty Opinions recommendation of AMP-activated protein kinase phosphorylates and desensitizes smooth muscle myosin light chain kinase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1115415.571445 ◽

2008 ◽

Author(s):

Steve Rattigan

Keyword(s):

Smooth Muscle ◽

Protein Kinase ◽

Light Chain ◽

Myosin Light Chain Kinase ◽

Myosin Light Chain ◽

Smooth Muscle Myosin ◽

Amp Activated Protein Kinase ◽

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Faculty Opinions recommendation of Polymorphisms in the myosin light chain kinase gene that confer risk of severe sepsis are associated with a lower risk of asthma.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1163897.625731 ◽

2009 ◽

Author(s):

Alejandro Schaffer

Keyword(s):

Severe Sepsis ◽

Light Chain ◽

Myosin Light Chain Kinase ◽

Myosin Light Chain ◽

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Lipopolysaccharide-Induced Increase in Intestinal Epithelial Tight Permeability Is Mediated by Toll-Like Receptor 4/Myeloid Differentiation Primary Response 88 (MyD88) Activation of Myosin Light Chain Kinase Expression

American Journal Of Pathology ◽

10.1016/j.ajpath.2017.08.005 ◽

2017 ◽

Vol 187 (12) ◽

pp. 2698-2710 ◽

Author(s):

Meghali Nighot ◽

Rana Al-Sadi ◽

Shuhong Guo ◽

Manmeet Rawat ◽

Prashant Nighot ◽

...

Keyword(s):

Light Chain ◽

Myosin Light Chain Kinase ◽

Myosin Light Chain ◽

Primary Response ◽

Myeloid Differentiation ◽

Intestinal Epithelial ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Kinase Expression

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Characterization of the calmodulin-binding and catalytic domains in skeletal muscle myosin light chain kinase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)39177-9 ◽

1985 ◽

Vol 260 (20) ◽

pp. 11275-11285 ◽

Author(s):

A M Edelman ◽

K Takio ◽

D K Blumenthal ◽

R S Hansen ◽

K A Walsh ◽

...

Keyword(s):

Skeletal Muscle ◽

Light Chain ◽

Myosin Light Chain Kinase ◽

Myosin Light Chain ◽

Skeletal Muscle Myosin ◽

Calmodulin Binding ◽

Catalytic Domains ◽

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Protein kinase C modulates in vitro phosphorylation of the smooth muscle heavy meromyosin by myosin light chain kinase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)47225-5 ◽

1984 ◽

Vol 259 (14) ◽

pp. 8808-8814 ◽

Author(s):

M Nishikawa ◽

J R Sellers ◽

R S Adelstein ◽

H Hidaka

Keyword(s):

Smooth Muscle ◽

Protein Kinase C ◽

Protein Kinase ◽

Light Chain ◽

Myosin Light Chain Kinase ◽

Myosin Light Chain ◽

Heavy Meromyosin ◽

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Characterization and bacterial expression of the Dictyostelium myosin light chain kinase cDNA. Identification of an autoinhibitory domain

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)98513-3 ◽

1991 ◽

Vol 266 (24) ◽

pp. 16044-16049

Author(s):

J.L. Tan ◽

J.A. Spudich

Keyword(s):

Light Chain ◽

Myosin Light Chain Kinase ◽

Myosin Light Chain ◽

Bacterial Expression ◽

Autoinhibitory Domain ◽

Dictyostelium Myosin

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Characterization of chicken skeletal muscle myosin light chain kinase. Evidence for muscle-specific isozymes.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(20)71202-0 ◽

1985 ◽

Vol 260 (2) ◽

pp. 1020-1026

Author(s):

M H Nunnally ◽

S B Rybicki ◽

J T Stull

Keyword(s):

Skeletal Muscle ◽

Light Chain ◽

Myosin Light Chain Kinase ◽

Myosin Light Chain ◽

Skeletal Muscle Myosin ◽

Muscle Myosin ◽

Chicken Skeletal Muscle

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Phosphorylation of smooth muscle myosin at two distinct sites by myosin light chain kinase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)39206-2 ◽

1985 ◽

Vol 260 (18) ◽

pp. 10027-10031 ◽

Author(s):

M Ikebe ◽

D J Hartshorne

Keyword(s):

Smooth Muscle ◽

Light Chain ◽

Myosin Light Chain Kinase ◽

Myosin Light Chain ◽

Smooth Muscle Myosin ◽

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The carboxyl terminus of the smooth muscle myosin light chain kinase is expressed as an independent protein, telokin.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)54376-3 ◽

1991 ◽

Vol 266 (35) ◽

pp. 23945-23952

Author(s):

P.J. Gallagher ◽

B.P. Herring

Keyword(s):

Smooth Muscle ◽

Light Chain ◽

Myosin Light Chain Kinase ◽

Myosin Light Chain ◽

Smooth Muscle Myosin ◽

Carboxyl Terminus ◽

Muscle Myosin ◽

Independent Protein

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