Ruthenium-Catalyzed, Chemoselective and Regioselective Oxidation of Polyisobutene

2021 ◽  
Vol 143 (12) ◽  
pp. 4531-4535
Author(s):  
Liye Chen ◽  
Katerina G. Malollari ◽  
Adam Uliana ◽  
John F. Hartwig
Keyword(s):  
Regioselective Oxidation

A Short Synthesis of the Plant Alkaloid 4-Methyl-2,6-naphthyridine

2019 ◽  
Vol 16 (12) ◽  
pp. 931-934 ◽  
Author(s):  
Alexandra Kamlah ◽  
Franz Bracher
Keyword(s):  
Pyridine Ring ◽  
Cross Coupling ◽  
Antirrhinum Majus ◽  
New Synthesis ◽  
Short Synthesis ◽  
Regioselective Oxidation ◽  
Key Steps

: A new synthesis of the 2,6-naphthyridine alkaloid 4-methyl-2,6-naphthyridine from Antirrhinum majus has been developed. Key steps are a regioselective oxidation of 3-bromo-4,5- dimethylpyridine to the corresponding 4-formyl derivative, and the annulation of the second pyridine ring by Suzuki-Miyaura cross-coupling using (E)-2-ethoxyvinylboronic acid pinacol ester as a masked acetaldehyde equivalent. This protocol gives the alkaloid in four steps starting from commercially available 3,4-dimethylpyridine in 15% overall yield. This annulation protocol should be useful for the synthesis of other condensed pyridines as well.

Regioselective oxidation of 2-amino-3-aroyl-4,5-dialkylthiophenes by DMSO

2004 ◽  
Vol 14 (4) ◽  
pp. 929-933 ◽  
Author(s):  
Elizabeth Joshi ◽  
Mahendra D. Chordia ◽  
Timothy L. Macdonald ◽  
Joel Linden ◽  
Ray Olsson
Keyword(s):  
Regioselective Oxidation

A new synthetic method for γ-butyrolactols by the paladium-catalyzed regioselective oxidation of 1-alken-4-ols

1988 ◽  
Vol 29 (40) ◽  
pp. 5181-5184 ◽  
Author(s):  
Junzo Nokami ◽  
Hideki Ogawa ◽  
Shinya Miyamoto ◽  
Tadakatsu Mandai ◽  
Shoji Wakabayashi ◽  
...  
Keyword(s):  
Synthetic Method ◽  
Regioselective Oxidation

Regioselective Oxidation of Fused-Pentagon Chlorofullerenes

2016 ◽  
Vol 55 (2) ◽  
pp. 543-545 ◽  
Author(s):  
Zhen-Qiang Zhang ◽  
Shu-Fen Chen ◽  
Cong-Li Gao ◽  
Ting Zhou ◽  
Gui-Juan Shan ◽  
...  
Keyword(s):  
Regioselective Oxidation
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