Kinetic DNA Self-Assembly: Simultaneously Co-folding Complementary DNA Strands into Identical Nanostructures

Author(s):  
Mengxi Zheng ◽  
Zhe Li ◽  
Longfei Liu ◽  
Mo Li ◽  
Victoria E. Paluzzi ◽  
...  
2017 ◽  
Vol 23 (62) ◽  
pp. 15759-15765 ◽  
Author(s):  
Sandeepa Kulala Vittala ◽  
Sajena Kanangat Saraswathi ◽  
Joshy Joseph

2002 ◽  
Vol 82 (1) ◽  
pp. 517-521 ◽  
Author(s):  
Irina Schumakovitch ◽  
Wilfried Grange ◽  
Torsten Strunz ◽  
Patricia Bertoncini ◽  
Hans-Joachim Güntherodt ◽  
...  

2009 ◽  
Vol 37 (17) ◽  
pp. e112-e112 ◽  
Author(s):  
Éva Hegedüs ◽  
Endre Kókai ◽  
Alexander Kotlyar ◽  
Viktor Dombrádi ◽  
Gábor Szabó

2019 ◽  
Vol 21 (1) ◽  
pp. 469-493 ◽  
Author(s):  
Dominic Scalise ◽  
Rebecca Schulman

In recent years, a diverse set of mechanisms have been developed that allow DNA strands with specific sequences to sense information in their environment and to control material assembly, disassembly, and reconfiguration. These sequences could serve as the inputs and outputs for DNA computing circuits, enabling DNA circuits to act as chemical information processors to program complex behavior in chemical and material systems. This review describes processes that can be sensed and controlled within such a paradigm. Specifically, there are interfaces that can release strands of DNA in response to chemical signals, wavelengths of light, pH, or electrical signals, as well as DNA strands that can direct the self-assembly and dynamic reconfiguration of DNA nanostructures, regulate particle assemblies, control encapsulation, and manipulate materials including DNA crystals, hydrogels, and vesicles. These interfaces have the potential to enable chemical circuits to exert algorithmic control over responsive materials, which may ultimately lead to the development of materials that grow, heal, and interact dynamically with their environments.


2002 ◽  
Vol 18 (8) ◽  
pp. 1021-1033 ◽  
Author(s):  
P.-F. Baisnee ◽  
S. Hampson ◽  
P. Baldi

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Chensheng Zhou ◽  
Heng Luo ◽  
Xiaolu Feng ◽  
Xingwang Li ◽  
Jie Zhu ◽  
...  

DNA self-assembly is a nanotechnology that folds DNA into desired shapes. Self-assembled DNA nanostructures, also known as origami, are increasingly valuable in nanomaterial and biosensing applications. Two ways to use DNA nanostructures in medicine are to form nanoarrays, and to work as vehicles in drug delivery. The DNA nanostructures perform well as a biomaterial in these areas because they have spatially addressable and size controllable properties. However, manually designing complementary DNA sequences for self-assembly is a technically demanding and time consuming task, which makes it advantageous for computers to do this job instead. We have developed a web server, FOLDNA, which can automatically design 2D self-assembled DNA nanostructures according to custom pictures and scaffold sequences provided by the users. It is the first web server to provide an entirely automatic design of self-assembled DNA nanostructure, and it takes merely a second to generate comprehensive information for molecular experiments including: scaffold DNA pathways, staple DNA directions, and staple DNA sequences. This program could save as much as several hours in the designing step for each DNA nanostructure. We randomly selected some shapes and corresponding outputs from our server and validated its performance in molecular experiments.


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