Probing Conformational Exchange Dynamics in a Short-Lived Protein Folding Intermediate by Real-Time Relaxation–Dispersion NMR

2017 ◽  
Vol 139 (3) ◽  
pp. 1065-1068 ◽  
Author(s):  
Rémi Franco ◽  
Sergio Gil-Caballero ◽  
Isabel Ayala ◽  
Adrien Favier ◽  
Bernhard Brutscher
Keyword(s):  
Protein Folding ◽  
Real Time ◽  
Relaxation Dispersion ◽  
Conformational Exchange ◽  
Folding Intermediate ◽  
Time Relaxation ◽  
Relaxation Dispersion Nmr

scholarly journals The Energetics of a Three-State Protein Folding System Probed by High-Pressure Relaxation Dispersion NMR Spectroscopy

2015 ◽  
Vol 54 (38) ◽  
pp. 11157-11161 ◽  
Author(s):  
Vitali Tugarinov ◽  
David S. Libich ◽  
Virginia Meyer ◽  
Julien Roche ◽  
G. Marius Clore
Keyword(s):  
High Pressure ◽  
Protein Folding ◽  
Nmr Spectroscopy ◽  
Relaxation Dispersion ◽  
Pressure Relaxation ◽  
Relaxation Dispersion Nmr

Real-Time NMR Characterization of Structure and Dynamics in a Transiently Populated Protein Folding Intermediate

2012 ◽  
Vol 134 (19) ◽  
pp. 8066-8069 ◽  
Author(s):  
Enrico Rennella ◽  
Thomas Cutuil ◽  
Paul Schanda ◽  
Isabel Ayala ◽  
Vincent Forge ◽  
...  
Keyword(s):  
Protein Folding ◽  
Real Time ◽  
Folding Intermediate ◽  
Structure And Dynamics ◽  
Nmr Characterization

scholarly journals Atomistic picture of conformational exchange in a T4 lysozyme cavity mutant: an experiment-guided molecular dynamics study

2016 ◽  
Vol 7 (6) ◽  
pp. 3602-3613 ◽  
Author(s):  
Pramodh Vallurupalli ◽  
Nilmadhab Chakrabarti ◽  
Régis Pomès ◽  
Lewis E. Kay
Keyword(s):  
Molecular Dynamics ◽  
Molecular Dynamics Simulations ◽  
Relaxation Dispersion ◽  
Conformational Exchange ◽  
T4 Lysozyme ◽  
Nmr Techniques ◽  
Relaxation Dispersion Nmr ◽  
Dynamics Simulations

Relaxation-dispersion NMR techniques and molecular dynamics simulations have been used to understand how a cavity mutant of T4 lysozyme interconverts between two compact conformations.

scholarly journals Relaxation Dispersion NMR Spectroscopy as a Tool for Detailed Studies of Protein Folding

2009 ◽  
Vol 96 (6) ◽  
pp. 2045-2054 ◽  
Author(s):  
Philipp Neudecker ◽  
Patrik Lundström ◽  
Lewis E. Kay
Keyword(s):  
Protein Folding ◽  
Nmr Spectroscopy ◽  
Relaxation Dispersion ◽  
Relaxation Dispersion Nmr

The Energetics of a Three-State Protein Folding System Probed by High-Pressure Relaxation Dispersion NMR Spectroscopy

2015 ◽  
Vol 127 (38) ◽  
pp. 11309-11313
Author(s):  
Vitali Tugarinov ◽  
David S. Libich ◽  
Virginia Meyer ◽  
Julien Roche ◽  
G. Marius Clore
Keyword(s):  
High Pressure ◽  
Protein Folding ◽  
Nmr Spectroscopy ◽  
Relaxation Dispersion ◽  
Pressure Relaxation ◽  
Relaxation Dispersion Nmr

Cooperativity of a Protein Folding Reaction Probed at Multiple Chain Positions by Real-Time 2D NMR Spectroscopy†

Biochemistry ◽  
2000 ◽  
Vol 39 (27) ◽  
pp. 7910-7919 ◽  
Author(s):  
Clemens Steegborn ◽  
Henriette Schneider-Hassloff ◽  
Markus Zeeb ◽  
Jochen Balbach
Keyword(s):  
Protein Folding ◽  
Nmr Spectroscopy ◽  
Real Time ◽  
2D Nmr ◽  
2D Nmr Spectroscopy ◽  
Multiple Chain
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