Stereoselective and Site-Specific Allylic Alkylation of Amino Acids and Small Peptides via a Pd/Cu Dual Catalysis

2017 ◽  
Vol 139 (29) ◽  
pp. 9819-9822 ◽  
Author(s):  
Xiaohong Huo ◽  
Rui He ◽  
Jingke Fu ◽  
Jiacheng Zhang ◽  
Guoqiang Yang ◽  
...  
Keyword(s):  
Amino Acids ◽  
Allylic Alkylation ◽  
Small Peptides ◽  
Site Specific ◽  
Dual Catalysis

scholarly journals Selective Recognition of Amino Acids and Peptides by Small Supramolecular Receptors

Molecules ◽  
2020 ◽  
Vol 26 (1) ◽  
pp. 106
Author(s):  
Joana N. Martins ◽  
João Carlos Lima ◽  
Nuno Basílio
Keyword(s):  
Amino Acids ◽  
Selective Recognition ◽  
Great Promise ◽  
Macrocyclic Compounds ◽  
Synthetic Receptors ◽  
Small Peptides ◽  
Molecular Imprinted Polymers ◽  
Polymeric Systems ◽  
Physiological Conditions ◽  
Level Information

To this day, the recognition and high affinity binding of biomolecules in water by synthetic receptors remains challenging, while the necessity for systems for their sensing, transport and modulation persists. This problematic is prevalent for the recognition of peptides, which not only have key roles in many biochemical pathways, as well as having pharmacological and biotechnological applications, but also frequently serve as models for the study of proteins. Taking inspiration in nature and on the interactions that occur between several receptors and peptide sequences, many researchers have developed and applied a variety of different synthetic receptors, as is the case of macrocyclic compounds, molecular imprinted polymers, organometallic cages, among others, to bind amino acids, small peptides and proteins. In this critical review, we present and discuss selected examples of synthetic receptors for amino acids and peptides, with a greater focus on supramolecular receptors, which show great promise for the selective recognition of these biomolecules in physiological conditions. We decided to focus preferentially on small synthetic receptors (leaving out of this review high molecular weight polymeric systems) for which more detailed and accurate molecular level information regarding the main structural and thermodynamic features of the receptor biomolecule assemblies is available.

scholarly journals Biosynthetic production of 13C-labeled amino acids with site-specific enrichment.

1982 ◽  
Vol 257 (3) ◽  
pp. 1224-1230
Author(s):  
D.M. LeMaster ◽  
J.E. Cronan
Keyword(s):  
Amino Acids ◽  
Site Specific

scholarly journals Correction to Efficient Site-Specific Prokaryotic and Eukaryotic Incorporation of Halotyrosine Amino Acids into Proteins

2020 ◽  
Author(s):  
Hyo Sang Jang ◽  
Xiaodong Gu ◽  
Richard B. Cooley ◽  
Joseph J. Porter ◽  
Rachel L. Henson ◽  
...  
Keyword(s):  
Amino Acids ◽  
Site Specific

scholarly journals Identification of the target amino acids in the site-specific inactivation of triose phosphate isomerase by ferrate anion.

1983 ◽  
Vol 258 (21) ◽  
pp. 13148-13154 ◽  
Author(s):  
J Steczko ◽  
M Hermodson ◽  
B Axelrod ◽  
E Dziembor-Kentzer
Keyword(s):  
Amino Acids ◽  
Triose Phosphate Isomerase ◽  
Site Specific ◽  
Triose Phosphate

ChemInform Abstract: Synthesis and Site-Specific Incorporation of Red-Shifted Azobenzene Amino Acids into Proteins.

ChemInform ◽  
2016 ◽  
Vol 47 (19) ◽  
Author(s):  
Alford A. John ◽  
Carlo P. Ramil ◽  
Yulin Tian ◽  
Gang Cheng ◽  
Qing Lin
Keyword(s):  
Amino Acids ◽  
Site Specific

Site-specific mutagenesis with unnatural amino acids

1989 ◽  
Vol 14 (10) ◽  
pp. 400-403 ◽  
Author(s):  
Spencer J. Anthony-Cahill ◽  
Michael C. Griffith ◽  
Christopher J. Noren ◽  
Daniel J. Suich ◽  
Peter G. Schultz
Keyword(s):  
Amino Acids ◽  
Unnatural Amino Acids ◽  
Site Specific
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