Carbonic Anhydrase Inhibitors:  Perfluoroalkyl/Aryl-Substituted Derivatives of Aromatic/Heterocyclic Sulfonamides as Topical Intraocular Pressure-Lowering Agents with Prolonged Duration of Action

Prolonged Duration ◽

Pressure Lowering ◽

Derivatives Of ◽

Aromatic Heterocyclic ◽

Aryl Substituted Derivatives

Carbonic anhydrase inhibitors – part 70. Synthesis and ocular pharmacology of a new class of water-soluble, topically effective intraocular pressure lowering agents derived from nicotinic acid and aromatic/heterocyclic sulfonamides

10.1016/s0223-5234(99)00212-3 ◽

1999 ◽

Vol 34 (10) ◽

pp. 799-808 ◽

Cited By ~ 9

Author(s):

C Supuran

Keyword(s):

Intraocular Pressure ◽

Carbonic Anhydrase ◽

Nicotinic Acid ◽

Water Soluble ◽

New Class ◽

Pressure Lowering ◽

Aromatic Heterocyclic ◽

Ocular Pharmacology

Carbonic Anhydrase Inhibitors. Water-Soluble, Topically Effective Intraocular Pressure Lowering Agents Derived from Isonicotinic Acid and Aromatic/Heterocyclic Sulfonamides: Is the Tail More Important than the Ring?

Journal of Enzyme Inhibition ◽

10.3109/14756369909030336 ◽

1999 ◽

Vol 14 (6) ◽

pp. 457-474 ◽

Cited By ~ 19

Author(s):

Luca Menabuoni ◽

Andrea Scozzafava ◽

Francesco Mincione ◽

Fabrizio Briganti ◽

Giovanna Mincione ◽

...

Keyword(s):

Intraocular Pressure ◽

Carbonic Anhydrase ◽

Isonicotinic Acid ◽

Water Soluble ◽

Pressure Lowering ◽

Aromatic Heterocyclic

Carbonic Anhydrase Inhibitors. Synthesis of Water-Soluble, Topically Effective, Intraocular Pressure-Lowering Aromatic/Heterocyclic Sulfonamides Containing Cationic or Anionic Moieties: Is the Tail More Important than the Ring?1

Journal of Medicinal Chemistry ◽

10.1021/jm9900523 ◽

1999 ◽

Vol 42 (14) ◽

pp. 2641-2650 ◽

Cited By ~ 192

Author(s):

Andrea Scozzafava ◽

Luca Menabuoni ◽

Francesco Mincione ◽

Fabrizio Briganti ◽

Giovanna Mincione ◽

...

Keyword(s):

Intraocular Pressure ◽

Carbonic Anhydrase ◽

Water Soluble ◽

Pressure Lowering ◽

Aromatic Heterocyclic

ChemInform Abstract: Carbonic Anhydrase Inhibitors. Part 70. Synthesis and Ocular Pharmacology of a New Class of Water-Soluble, Topically Effective Intraocular Pressure Lowering Agents Derived from Nicotinic Acid and Aromatic/Heterocyclic Sulfonamides

ChemInform ◽

10.1002/chin.200006134 ◽

2010 ◽

Vol 31 (6) ◽

pp. no-no

Author(s):

Claudiu T. Supuran ◽

Andrea Scozzafava ◽

Luca Menabuoni ◽

Francesco Mincione ◽

Fabrizio Briganti ◽

...

Keyword(s):

Intraocular Pressure ◽

Carbonic Anhydrase ◽

Nicotinic Acid ◽

Water Soluble ◽

New Class ◽

Pressure Lowering ◽

Aromatic Heterocyclic ◽

Ocular Pharmacology

Comparison of Intraocular Pressure Lowering by Topical and Systemic Carbonic Anhydrase Inhibitors in the Rabbit

Journal of Ocular Pharmacology and Therapeutics ◽

10.1089/jop.1999.15.51 ◽

1999 ◽

Vol 15 (1) ◽

pp. 51-57 ◽

Cited By ~ 8

Author(s):

MAHER M. FANOUS ◽

PRATAP CHALLA ◽

THOMAS H. MAREN

Keyword(s):

Intraocular Pressure ◽

Carbonic Anhydrase ◽

Carbonic anhydrase inhibitors – Part 78. Synthesis of water-soluble sulfonamides incorporating β-alanyl moieties, possessing long lasting-intraocular pressure lowering properties via the topical route

10.1016/s0223-5234(00)00130-6 ◽

2000 ◽

Vol 35 (3) ◽

pp. 309-321 ◽

Cited By ~ 9

Author(s):

C Supuran

Keyword(s):

Intraocular Pressure ◽

Carbonic Anhydrase ◽

Water Soluble ◽

2-Benzylpiperazine: A new scaffold for potent human carbonic anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agents

10.1016/j.ejmech.2018.04.002 ◽

2018 ◽

Vol 151 ◽

pp. 363-375 ◽

Cited By ~ 16

Author(s):

Niccolò Chiaramonte ◽

Silvia Bua ◽

Marta Ferraroni ◽

Alessio Nocentini ◽

Alessandro Bonardi ◽

...

Keyword(s):

Intraocular Pressure ◽

Carbonic Anhydrase ◽

Enzyme Inhibition ◽

New Class ◽

Pressure Lowering ◽

Human Carbonic Anhydrase

Carbonic anhydrase inhibitors. Part 60##See ref. [1]. The topical intraocular pressure-lowering properties of metal complexes of a heterocyclic sulfonamide: influence of the metal ion upon biological activity

10.1016/s0223-5234(00)80028-8 ◽

1999 ◽

Vol 34 (7-8) ◽

pp. 585-595 ◽

Cited By ~ 3

Author(s):

Claudiu T. Supuran ◽

Andrea Scozzafava ◽

Francesco Mincione ◽

Luca Menabuoni ◽

Fabrizio Briganti ◽

...

Keyword(s):

Biological Activity ◽

Intraocular Pressure ◽

Carbonic Anhydrase ◽

Metal Complexes ◽

Metal Ion ◽

Carbonic anhydrase inhibitors: Design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2005.06.054 ◽

2005 ◽

Vol 15 (17) ◽

pp. 3821-3827 ◽

Cited By ~ 16

Author(s):

Francesco Mincione ◽

Michele Starnotti ◽

Emanuela Masini ◽

Lucia Bacciottini ◽

Chiara Scrivanti ◽

...

Keyword(s):

Intraocular Pressure ◽

Carbonic Anhydrase ◽

Rabbit Model ◽

Pressure Lowering ◽

Lowering Activity

Carbonic anhydrase inhibitors: sulfonamides incorporating furan-, thiophene- and pyrrole-carboxamido groups possess strong topical intraocular pressure lowering properties as aqueous suspensions

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(00)00143-7 ◽

2000 ◽

Vol 8 (8) ◽

pp. 2145-2155 ◽

Cited By ~ 42

Author(s):

Monica Ilies ◽

Claudiu T. Supuran ◽

Andrea Scozzafava ◽

Angela Casini ◽

Francesco Mincione ◽

...

Keyword(s):

Intraocular Pressure ◽

Carbonic Anhydrase ◽

Aqueous Suspensions ◽