scholarly journals Structure–Activity Relationship and in Vitro and in Vivo Evaluation of the Potent Cytotoxic Anti-microtubule AgentN-(4-Methoxyphenyl)-N,2,6-trimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-aminium Chloride and Its Analogues As Antitumor Agents

2013 ◽  
Vol 56 (17) ◽  
pp. 6829-6844 ◽  
Author(s):  
Aleem Gangjee ◽  
Ying Zhao ◽  
Sudhir Raghavan ◽  
Cristina C. Rohena ◽  
Susan L. Mooberry ◽  
...  
Keyword(s):  
Antitumor Agents ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
In Vivo Evaluation ◽  
Structure Activity

Synthesis of new generation triazolyl- and isoxazolyl-containing 6-nitro-2,3-dihydroimidazooxazoles as anti-TB agents: in vitro, structure–activity relationship, pharmacokinetics and in vivo evaluation

2015 ◽  
Vol 13 (12) ◽  
pp. 3610-3624 ◽  
Author(s):  
Gurunadham Munagala ◽  
Kushalava Reddy Yempalla ◽  
Samsher Singh ◽  
Sumit Sharma ◽  
Nitin Pal Kalia ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
In Vivo Evaluation ◽  
Structure Activity ◽  
New Generation

Promising nitroimidazoloxazole scaffold gives another novel triazolyl-containing 6-nitro-2,3-dihydroimidazooxazole as anti-TB lead.

Discovery and Structure−Activity Relationship of Antagonists of B-Cell Lymphoma 2 Family Proteins with Chemopotentiation Activity in Vitro and in Vivo

2006 ◽  
Vol 49 (3) ◽  
pp. 1165-1181 ◽  
Author(s):  
Michael D. Wendt ◽  
Wang Shen ◽  
Aaron Kunzer ◽  
William J. McClellan ◽  
Milan Bruncko ◽  
...  
Keyword(s):  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of
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