Modeling Subtype-Selective Agonists Binding with α4β2 and α7 Nicotinic Acetylcholine Receptors:  Effects of Local Binding and Long-Range Electrostatic Interactions

Acetylcholine Receptors ◽

Electrostatic Interactions ◽

Nicotinic Acetylcholine ◽

Selective Agonists ◽

Subtype Selective ◽

Local Binding

Role of α7 nicotinic acetylcholine receptors in regulating tumor necrosis factor-α (TNF-α) as revealed by subtype selective agonists

Journal of Neuroimmunology ◽

10.1016/j.jneuroim.2011.08.007 ◽

2011 ◽

Vol 239 (1-2) ◽

pp. 37-43 ◽

Cited By ~ 18

Author(s):

Jinhe Li ◽

Suzanne L. Mathieu ◽

Richard Harris ◽

Jianguo Ji ◽

David J. Anderson ◽

...

Keyword(s):

Acetylcholine Receptors ◽

Tumor Necrosis ◽

Tnf Α ◽

Selective Agonists ◽

Factor Α ◽

Subtype Selective ◽

Necrosis Factor

Role of α7 nicotinic acetylcholine receptors in regulating tumor necrosis factor-α (TNF-α) as Revealed by subtype selective agonists

Biochemical Pharmacology ◽

10.1016/j.bcp.2009.06.092 ◽

2009 ◽

Vol 78 (7) ◽

pp. 924-925

Author(s):

Jinhe Li ◽

Suzanne L. Mathieu ◽

Richard Harris ◽

Jianguo Ji ◽

David J. Anderson ◽

...

Keyword(s):

Acetylcholine Receptors ◽

Tumor Necrosis ◽

Tnf Α ◽

Selective Agonists ◽

Factor Α ◽

Subtype Selective ◽

Necrosis Factor

An Unaltered Orthosteric Site and a Network of Long-Range Allosteric Interactions for PNU-120596 in α7 Nicotinic Acetylcholine Receptors

Chemistry & Biology ◽

10.1016/j.chembiol.2015.06.018 ◽

2015 ◽

Vol 22 (8) ◽

pp. 1063-1073 ◽

Cited By ~ 5

Author(s):

Christopher B. Marotta ◽

Henry A. Lester ◽

Dennis A. Dougherty

Keyword(s):

Long Range ◽

Acetylcholine Receptors ◽

Nicotinic Acetylcholine ◽

Allosteric Interactions ◽

Design, Synthesis, and Pharmacological Characterization of Novel Spirocyclic Quinuclidinyl-Δ2-Isoxazoline Derivatives as Potent and Selective Agonists of α7 Nicotinic Acetylcholine Receptors

ChemMedChem ◽

10.1002/cmdc.201000514 ◽

2011 ◽

Vol 6 (5) ◽

pp. 889-903 ◽

Cited By ~ 22

Author(s):

Clelia Dallanoce ◽

Pietro Magrone ◽

Carlo Matera ◽

Fabio Frigerio ◽

Giovanni Grazioso ◽

...

Keyword(s):

Acetylcholine Receptors ◽

Pharmacological Characterization ◽

Nicotinic Acetylcholine ◽

Design Synthesis ◽

Selective Agonists

Engineered Conotoxin Differentially Blocks and Discriminates Rat and Human α7 Nicotinic Acetylcholine Receptors

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.0c02079 ◽

2021 ◽

Author(s):

Shuai Wang ◽

Xiaopeng Zhu ◽

Manqi Zhangsun ◽

Yong Wu ◽

Jinpeng Yu ◽

...

Keyword(s):

Acetylcholine Receptors ◽

Nicotinic Acetylcholine ◽

GTS-21 has cell-specific anti-inflammatory effects independent of α7 nicotinic acetylcholine receptors

PLoS ONE ◽

10.1371/journal.pone.0214942 ◽

2019 ◽

Vol 14 (4) ◽

pp. e0214942 ◽

Cited By ~ 10

Author(s):

Brijesh K. Garg ◽

Ralph H. Loring

Keyword(s):

Acetylcholine Receptors ◽

Nicotinic Acetylcholine ◽

Anti Inflammatory

Explore the role of lymphocyte antigen 6/urokinase-type plasminogen activator receptor related protein-1 in melanoma promoting caused by signaling of α7-nicotinic acetylcholine receptors

Journal of the Neurological Sciences ◽

10.1016/j.jns.2017.08.3497 ◽

2017 ◽

Vol 381 ◽

pp. 456-457

Author(s):

P.J. Lin ◽

S.H. Jee ◽

C.Y. Chang

Keyword(s):

Plasminogen Activator ◽

Acetylcholine Receptors ◽

Related Protein ◽

Nicotinic Acetylcholine ◽

Type Plasminogen Activator ◽

Urokinase Type Plasminogen Activator ◽

Plasminogen Activator Receptor

Inhibition of human α7 nicotinic acetylcholine receptors by open channel blockers of N -methyl-D -aspartate receptors

British Journal of Pharmacology ◽

10.1038/sj.bjp.0705559 ◽

2003 ◽

Vol 140 (7) ◽

pp. 1313-1319 ◽

Cited By ~ 57

Author(s):

Peter D Maskell ◽

Pauline Speder ◽

Nigel R Newberry ◽

Isabel Bermudez

Keyword(s):

Acetylcholine Receptors ◽

Open Channel ◽

Channel Blockers ◽

Nicotinic Acetylcholine ◽

A Novel α2/α4 Subtype-selective Positive Allosteric Modulator of Nicotinic Acetylcholine Receptors Acting from the C-tail of an α Subunit

Journal of Biological Chemistry ◽

10.1074/jbc.m115.676551 ◽

2015 ◽

Vol 290 (48) ◽

pp. 28834-28846 ◽

Cited By ~ 11

Author(s):

Jingyi Wang ◽

Alexander Kuryatov ◽

Zhuang Jin ◽

Jack Norleans ◽

Theodore M. Kamenecka ◽

...

Keyword(s):

Acetylcholine Receptors ◽

Allosteric Modulator ◽

Positive Allosteric Modulator ◽

Nicotinic Acetylcholine ◽

Α Subunit ◽

Subtype Selective

Role of α7 nicotinic acetylcholine receptors in the synaptic transmission at the frog neuromuscular contacts

Bulletin of Experimental Biology and Medicine ◽

10.47056/0365-9615-2021-172-11-564-569 ◽

2021 ◽

Vol 172 (11) ◽

pp. 564-569

Author(s):

O. A. Lenina ◽

◽

I. V. Kovyazina ◽

Keyword(s):

Synaptic Transmission ◽

Acetylcholine Receptors ◽

Nicotinic Acetylcholine ◽