Analysis of Amide Bond Formation with an α-Hydroxy-β-amino Acid Derivative, 3-Amino-2-hydroxy-4-phenylbutanoic Acid, as an Acyl Component:  Byproduction of Homobislactone

2001 ◽  
Vol 66 (16) ◽  
pp. 5537-5544 ◽  
Author(s):  
Yoshio Hayashi ◽  
Yuko Kinoshita ◽  
Koushi Hidaka ◽  
Aiko Kiso ◽  
Hirokazu Uchibori ◽  
...  
Keyword(s):  
Amino Acid ◽  
Acid Derivative ◽  
Bond Formation ◽  
Amide Bond ◽  
Amino Acid Derivative ◽  
Amide Bond Formation

scholarly journals Liposomes Can Achieve Enantioselective C–C Bond Formation of an α-Amino Acid Derivative in Aqueous Media

ACS Omega ◽  
2017 ◽  
Vol 2 (1) ◽  
pp. 91-97 ◽  
Author(s):  
Fumihiko Iwasaki ◽  
Keishi Suga ◽  
Yukihiro Okamoto ◽  
Hiroshi Umakoshi
Keyword(s):  
Amino Acid ◽  
Acid Derivative ◽  
Bond Formation ◽  
Aqueous Media ◽  
Amino Acid Derivative

Diethylphosphoryl-OxymaB (DEPO-B) as a Solid Coupling Reagent for Amide Bond Formation

2018 ◽  
Vol 16 (1) ◽  
pp. 30-33
Author(s):  
Ashish Kumar ◽  
Yahya E. Jad ◽  
Ayman El-Faham ◽  
Beatriz G. de la Torre ◽  
Fernando Albericio
Keyword(s):  
Bond Formation ◽  
Hydrolytic Stability ◽  
Solid Material ◽  
Amide Bond ◽  
Amide Bond Formation ◽  
Coupling Reagent

A new phosphonium based coupling reagent DEPO-B has been synthesized from 5- (hydroxyimino)-1,3-dimethylpyrimidine-2,4,6 (1H,3H,5H)-trione (Oxyma B) and diethyl chlorophosphate in presence of base. It is a solid material and the hydrolytic stability and solubility was evaluated for confirming its capability for usage in automated peptide synthesizer.

A Review of Amide Bond Formation in Microwave Organic Synthesis

2014 ◽  
Vol 11 (4) ◽  
pp. 592-604 ◽  
Author(s):  
Natalia Lukasik ◽  
Ewa Wagner-Wysiecka
Keyword(s):  
Organic Synthesis ◽  
Bond Formation ◽  
Amide Bond ◽  
Amide Bond Formation

Synthesis of amino acid derivative Schiff base copper(II) complexes by microwave and wet mechanochemical methods

2021 ◽  
Vol 98 (1) ◽  
pp. 100004
Author(s):  
Nao Otani ◽  
Tetsundo Furuya ◽  
Natsuki Katsuumi ◽  
Tomoyuki Haraguchi ◽  
Takashiro Akitsu
Keyword(s):  
Schiff Base ◽  
Amino Acid ◽  
Acid Derivative ◽  
Amino Acid Derivative

Resolution of racemic mixture of α-amino acid derivative through composite membrane

2011 ◽  
Vol 378 (1-2) ◽  
pp. 531-540 ◽  
Author(s):  
Kripal Singh ◽  
Pravin G. Ingole ◽  
Jayesh Chaudhari ◽  
Harshad Bhrambhatt ◽  
Amit Bhattacharya ◽  
...  
Keyword(s):  
Amino Acid ◽  
Acid Derivative ◽  
Composite Membrane ◽  
Amino Acid Derivative ◽  
Racemic Mixture

A computational study on the mechanism of ynamide-mediated amide bond formation from carboxylic acids and amines

2017 ◽  
Vol 15 (30) ◽  
pp. 6367-6374 ◽  
Author(s):  
Song-Lin Zhang ◽  
Hai-Xing Wan ◽  
Zhu-Qin Deng
Keyword(s):  
Reaction Mechanism ◽  
Carboxylic Acids ◽  
Computational Study ◽  
Bond Formation ◽  
Amide Bond ◽  
Reactivity Pattern ◽  
Amide Bond Formation ◽  
Coupling Reagent ◽  
Catalytic Effects ◽  
Acid Substrate

A detailed computational study is presented on the reaction mechanism of ynamide-mediated condensation of carboxylic acids with amines to produce amides, which elucidates the reactivity pattern of the coupling reagent ynamide and discloses crucial bifunctional catalytic effects of the carboxylic acid substrate during aminolysis.

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