Optimal Design and Characterization of Superparamagnetic Iron Oxide Nanoparticles Coated with Polyvinyl Alcohol for Targeted Delivery and Imaging†

2008 ◽  
Vol 112 (46) ◽  
pp. 14470-14481 ◽  
Author(s):  
Morteza Mahmoudi ◽  
Abdolreza Simchi ◽  
Mohammad Imani ◽  
Abbas S. Milani ◽  
Pieter Stroeve
Keyword(s):  
Iron Oxide ◽  
Optimal Design ◽  
Polyvinyl Alcohol ◽  
Iron Oxide Nanoparticles ◽  
Targeted Delivery ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles

scholarly journals Use of Superparamagnetic Iron Oxide Nanoparticles (SPIONs) via Multiple Imaging Modalities and Modifications to Reduce Cytotoxicity: An Educational Review

2020 ◽  
Vol 1 (1) ◽  
pp. 105-135
Author(s):  
Nicholas Nelson ◽  
John Port ◽  
Mukesh Pandey
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Targeted Delivery ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Positron Emission ◽  
Multiple Imaging ◽  
Specific Accumulation ◽  
Magnetic Resonance Imaging Mri

The aim of the present educational review on superparamagnetic iron oxide nanoparticles (SPIONs) is to inform and guide young scientists and students about the potential use and challenges associated with SPIONs. The present review discusses the basic concepts of magnetic resonance imaging (MRI), basic construct of SPIONs, cytotoxic challenges associated with SPIONs, shape and sizes of SPIONs, site-specific accumulation of SPIONs, various methodologies applied to reduce cytotoxicity including coatings with various materials, and application of SPIONs in targeted delivery of chemotherapeutics (Doxorubicin), biotherapeutics (DNA, siRNA), and positron emission tomography (PET) imaging applications.

Synthesis and characterization of multifunctional superparamagnetic iron oxide nanoparticles (SPION)/C60 nanocomposites assembled by fullerene–amine click chemistry

RSC Advances ◽  
2016 ◽  
Vol 6 (74) ◽  
pp. 70374-70382 ◽  
Author(s):  
Manuel Cano ◽  
Rebeca Núñez-Lozano ◽  
Yves Dumont ◽  
Chantal Larpent ◽  
Guillermo de la Cueva-Méndez
Keyword(s):  
Iron Oxide ◽  
Click Chemistry ◽  
Iron Oxide Nanoparticles ◽  
Antioxidant Activities ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Synthesis And Characterization ◽  
Oxide Nanoparticles

We used fullerene–amine click chemistry for the fabrication of SPION/C60 nanocomposites that bring together the superparamagnetic character conferred by the SPION-core and the photochemical and antioxidant activities provided by the C60.

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