Surpassingly Competitive Electromagnetic Field Enhancement at the Silica/Silver Interface for Selective Intracellular Surface Enhanced Raman Scattering Detection

ACS Nano ◽  
2015 ◽  
Vol 9 (3) ◽  
pp. 2820-2835 ◽  
Author(s):  
Darya Radziuk ◽  
Helmuth Möhwald
2007 ◽  
Vol 336-338 ◽  
pp. 2146-2148
Author(s):  
Yong Yang ◽  
Masayuki Nogami

Surface-enhanced Raman scattering (SERS) integrates high levels of sensitivity with spectroscopic precision and thus has tremendous potential for chemical and biomolecular sensing. The key to the wider application of Raman spectroscopy using roughened metallic surfaces is the development of highly enhancing substrates for analytical purposes, i.e., for better detection sensitivity of tracing contaminants and pollutants. Controlled methods for preparing nano-structured metals may provide more useful correlations between surface structure and signal enhancement. Here, we self-assembled silver nanorods on glass substrates for sensitive SERS substrates. The enhanced surface Raman scattering signals were observed and mainly attributed to the local field enhancement.


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