Synthesis and Cytotoxicity of a Salicylihalamide A Analogue

2008 ◽  
Vol 71 (5) ◽  
pp. 898-901 ◽  
Author(s):  
Shaoshan Tang ◽  
Karen L. Erickson
Keyword(s):  
Salicylihalamide A

ChemInform Abstract: Total Synthesis of (-)-Salicylihalamide A.

ChemInform ◽  
2010 ◽  
Vol 32 (52) ◽  
pp. no-no
Author(s):  
Barry B. Snider ◽  
Fengbin Song
Keyword(s):  
Total Synthesis ◽  
Salicylihalamide A

Total Synthesis of (−)-Salicylihalamide A

2001 ◽  
Vol 3 (12) ◽  
pp. 1817-1820 ◽  
Author(s):  
Barry B. Snider ◽  
Fengbin Song
Keyword(s):  
Total Synthesis ◽  
Salicylihalamide A

Synthesis and biological evaluation of a potent salicylihalamide A lactam analogue

2012 ◽  
Vol 10 (40) ◽  
pp. 8147 ◽  
Author(s):  
Dan Balan ◽  
Christopher J. Burns ◽  
Nicholas G. Fisk ◽  
Helmut Hügel ◽  
David C. S. Huang ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Salicylihalamide A ◽  
Synthesis And Biological Evaluation

scholarly journals Computational investigation of marine bioactive compounds reveals frigocyclinone as a potent inhibitor of Kaposi’s Sarcoma Associated Herpesvirus (KSHV) targets

2019 ◽  
Vol 12 (3) ◽  
pp. 1289-1302
Author(s):  
Nirmaladevi Ponnusamy ◽  
Rajasree Odumpatta ◽  
Pavithra Damodharan ◽  
Mohanapriya Arumugam
Keyword(s):  
Bioactive Compounds ◽  
Drug Targets ◽  
Kaposi's Sarcoma ◽  
Protein Structures ◽  
In Silico Analysis ◽  
Kaposi’S Sarcoma ◽  
The Stability ◽  
Salicylihalamide A ◽  
Experimental Structure

In the present study, in silico analysis was employed to identify the action of marine bioactive compounds against KSHV targets. Virulence factor analysis of KSHV from literature review, three proteins LANA1, vIRF3/LANA2 and PF-8 were identified as putative drug targets. The quality of protein structures play a significant role in the experimental structure validation and prediction, where the predicted structures may contain considerable errors was checked by SAVES v5.0 servers. By virtual screening four potential bioactive compounds Ascorbic acid, Salicylihalamide A, Salicylihalamide B and Frigocyclinone were predicted. One of the potential compounds of Frigocyclinone has acting against KSHV proteins. Hence, determined as the good lead molecule against KSHV. Molecular dynamic simulation studies revealed the stability of LANA1- Frigocyclinone complex and it could be a futuristic perspective chemical compound for Kaposi’s sarcoma.

scholarly journals A First Generation Total Synthesis of (+)-Salicylihalamide A

Synlett ◽  
2001 ◽  
Vol 2001 (Special Issue) ◽  
pp. 1019-1023 ◽  
Author(s):  
Amos B. Smith III ◽  
Junying Zheng
Keyword(s):  
Total Synthesis ◽  
First Generation ◽  
Salicylihalamide A
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