Cross-reactivity of IgE antibodies to allergens

Allergy ◽  
2001 ◽  
Vol 56 (6) ◽  
pp. 478-490 ◽  
Author(s):  
R. C. Aalberse ◽  
J. Akkerdaas ◽  
R. van Ree
Keyword(s):  
Cross Reactivity ◽  
Ige Antibodies

scholarly journals Peanut-specific IgE antibodies in asymptomatic Ghanaian children possibly caused by carbohydrate determinant cross-reactivity

2013 ◽  
Vol 132 (3) ◽  
pp. 639-647 ◽  
Author(s):  
Abena S. Amoah ◽  
Benedicta B. Obeng ◽  
Irene A. Larbi ◽  
Serge A. Versteeg ◽  
Yvonne Aryeetey ◽  
...  
Keyword(s):  
Specific Ige ◽  
Cross Reactivity ◽  
Ige Antibodies ◽  
Specific Ige Antibodies

The cross-reactivity of IgE antibodies with pollen allergens

1976 ◽  
Vol 58 (1) ◽  
pp. 129-139 ◽  
Author(s):  
Kristin M. Leiferman ◽  
Gerald J. Gleich
Keyword(s):  
Cross Reactivity ◽  
Pollen Allergens ◽  
Ige Antibodies ◽  
The Cross

The cross-reactivity of IgE antibodies with pollen allergens

1976 ◽  
Vol 58 (1) ◽  
pp. 140-148 ◽  
Author(s):  
Kristin M. Leiferman ◽  
Gerald J. Gleich ◽  
Richard T. Jones
Keyword(s):  
Cross Reactivity ◽  
Pollen Allergens ◽  
Ige Antibodies ◽  
The Cross

scholarly journals High-affinity allergen-specific human antibodies cloned from single IgE B cell transcriptomes

Science ◽  
2018 ◽  
Vol 362 (6420) ◽  
pp. 1306-1309 ◽  
Author(s):  
Derek Croote ◽  
Spyros Darmanis ◽  
Kari C. Nadeau ◽  
Stephen R. Quake
Keyword(s):  
B Cell ◽  
Immunoglobulin E ◽  
Variable Region ◽  
Cross Reactivity ◽  
Food Allergies ◽  
Ige Antibodies ◽  
High Affinity ◽  
Helminth Infections ◽  
Life Threatening ◽  
Antibody Class

Immunoglobulin E (IgE) antibodies protect against helminth infections but can also cause life-threatening allergic reactions. Despite their role in human health, the cells that produce these antibodies are rarely observed and remain enigmatic. We isolated single IgE B cells from individuals with food allergies and used single-cell RNA sequencing to elucidate the gene expression and splicing patterns unique to these cells. We identified a surprising example of convergent evolution in which IgE antibodies underwent identical gene rearrangements in unrelated individuals. Through the acquisition of variable region mutations, these IgE antibodies gained high affinity and unexpected cross-reactivity to the clinically important peanut allergens Ara h 2 and Ara h 3. These findings provide insight into IgE B cell transcriptomics and enable biochemical dissection of this antibody class.

Cross-reactivity of IgE antibodies to caddis fly with arthropoda and mollusca

1989 ◽  
Vol 84 (2) ◽  
pp. 174-183 ◽  
Author(s):  
V.L. Koshte ◽  
S.L. Kagen ◽  
R.C. Aalberse
Keyword(s):  
Cross Reactivity ◽  
Ige Antibodies ◽  
Caddis Fly
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