Biofeedback Control of Heart Rate Variability to Phobic Stimuli: A New Approach to Treating Spider Phobia

Author(s):  
George P. Prigatano ◽  
Harold J. Johnson
2006 ◽  
Vol 38 (Supplement) ◽  
pp. S506
Author(s):  
Filipe L. Medeiros ◽  
Luis E.C. Cardoso ◽  
Alfredo M. de Oliveira ◽  
Carlos E.B. Neves ◽  
Edil L. Santos

2000 ◽  
Vol 279 (1) ◽  
pp. H110-H115 ◽  
Author(s):  
I. Perlstein ◽  
A. Hoffman

A new approach to assess autonomic nervous system (ANS) activity and its response to drug action is presented. Our approach is based on the use of a cumulative plot of data obtained by power spectral analysis of heart rate variability, in defined frequency bands, during short time epochs (e.g., 2 min in rats). The substantial temporal variability in power evolving from the constant balancing nature of the ANS activity is minimized by this approach and produces a measurable index of ANS activity vs. time. The cumulative plot emphasizes the temporal response pattern of different components of the ANS and thereby facilitates the investigation of the kinetics of action of drugs affecting the ANS. We used this method to measure the activity of cholinergic drugs in freely moving Sabra rats. Bolus atropine doses between 0.5 and 2 mg/kg produced a similar magnitude of effect, reduction of the ascending slope by 0.003 power units/h, whereas the duration of this effect was dose dependent. A lower atropine dose (0.1 mg/kg) or 0.5 mg/kg scopolamine elevated the slope (0.074 and 0.054 power units/h for 206 and 216 min, respectively). The method was used similarly to assess the interaction between cholinergic drugs. Pretreatment with pyridostigmine produced temporal blockage of the anticholinergic activity of atropine.


2020 ◽  
Author(s):  
Mohammad Karimi Moridani ◽  
Seyed Kamaledin Setarehdan ◽  
Ali Motie Nasrabadi ◽  
Esmaeil Hajinasrollah

Abstract Background: This article aimed to explore the mortality prediction of cerebrovascular patients in the intensive care unit (ICU) by examining the important signals associated with these patients during different periods of admission in the intensive care unit, which is considered as one of the new topics in the medical field. Several approaches have been proposed for prediction in this area that each of these methods has been able to predict the mortality somewhat, but many of these techniques require the recording of a large amount of data from the patients, where the recording of all data is not possible in most cases; while this article focuses only on the heart rate variability (HRV) and systolic and diastolic blood pressure.Methods: In this paper, using the information obtained from the electrocardiogram (ECG) signal and blood pressure with the help of vital signal processing methods, how to change these signals during the patient's hospitalization will be initially checked. Then, the mortality prediction in patients with cerebral ischemia is evaluated using the features extracted from the return map generated by the signal of heart rate variability and blood pressure. To implement this paper, 80 recorded data from cerebral ischemic patients admitted to the intensive care unit, including ECG signal recording, systolic and diastolic blood pressure, and other physiological parameters are collected. Time of admission and time of death are labeled in all data.Results: The results indicate that the use of the new approach presented in this article can be compared with other methods or leads to better results. The accuracy, specificity, and sensitivity based on the novel features were, respectively, 97.7, 98.9, and 95.4 for cerebral ischemia disease with a prediction horizon of 0.5-1 hours before death.Conclusion: The perspective of the prediction horizons and the patients' length of stay with a new approach was taken into account in this article. The higher the prediction horizon, the nurses or associates of patients have more time to carry out therapeutic measures. To determine the patient's future status and analysis of the ECG signal and blood pressure, at least 7.8 hours of hospitalization is required, which has had a significant reduction compared with other methods.


2011 ◽  
Vol 10 (1) ◽  
pp. 25-31
Author(s):  
O. V. Yeremeyeva ◽  
V. S. Kormilez ◽  
S. I. Yeremeyev

The aim was to investigate the electroencephalography indexes dynamic caused by neurofeedback in athletes. The main results are that the neurobiofeedback cumulative effect on the electroencephalographic indexes in the high qualified athletes with the dominance of metabolic modulation of heart rate variability is carried out. The conclusions are that the interlobar reciprocal actions reorganization in a brain and the general changing of quantitative electroencephalogram indexes of all standard diapasons of frequency are revealed both in the locus of biofeedback control and overall brain convex surface.


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