Acid-labile Carbon Dioxide in Mammalian Muscle and the Hydrogen Ion Concentration of the Muscle Fibre

Nature ◽  
1944 ◽  
Vol 153 (3871) ◽  
pp. 54-55 ◽  
Author(s):  
E. J. CONWAY ◽  
P. J. FEARON
Keyword(s):  
Carbon Dioxide ◽  
Muscle Fibre ◽  
Hydrogen Ion ◽  
Ion Concentration ◽  
Labile Carbon ◽  
Hydrogen Ion Concentration ◽  
Mammalian Muscle ◽  
Acid Labile

scholarly journals REGULATION OF THE HYDROGEN ION CONCENTRATION AND ITS RELATION TO METABOLISM AND RESPIRATION IN THE STARFISH

1926 ◽  
Vol 10 (2) ◽  
pp. 345-358 ◽  
Author(s):  
Laurence Irving
Keyword(s):  
Carbon Dioxide ◽  
Sea Water ◽  
Carbon Dioxide Production ◽  
Hydrogen Ion ◽  
Ion Concentration ◽  
Coelomic Fluid ◽  
Vital Function ◽  
Hydrogen Ion Concentration ◽  
Optimum Ph ◽  
Patiria Miniata

The normal reaction of the cœlomic fluid in Patiria miniata and Asterias ochraceus is pH 7.6, and of the cæca, 6.7, compared with sea water at 8.3, all without salt error correction. A medium at pH 6.7–7.0 is optimum for the cæca for ciliary survival and digestion of protein, and is maintained by carbon dioxide production. The optimum pH found for carbon dioxide production is a true one for the effect of hydrogen ion concentration on the tissue. It does not represent an elimination gradient for carbon dioxide. Because the normal excised cæca maintain a definite hydrogen ion concentration and change their internal environment toward that as an optimum during life, there exists a regulatory process which is an important vital function.

scholarly journals The heat of rigor of mammalian muscle

1930 ◽  
Vol 107 (750) ◽  
pp. 214-222 ◽  
Keyword(s):  
Lactic Acid ◽  
Heat Production ◽  
Hydrogen Ion ◽  
Ion Concentration ◽  
Post Mortem ◽  
Rigor Mortis ◽  
Hydrogen Ion Concentration ◽  
Mammalian Muscle ◽  
Quantity Of Heat

The stiffening of muscle in rigor mortis is closely related to gelation of the muscle plasma (Smith, 1930). Neither the stiffening of the muscle (Hoet and Marks, 1926) nor the gelation of the plasma is immediately due to an increase in the hydrogen-ion concentration of the muscle, but, apart from the formation of lactic acid, no reaction is known to occur post-mortem which might be held responsible for the coagulation of the plasma. It was with a view to the detection of any such reaction that the following measurements of the heat production accompanying rigor mortis were made. The heat of rigor mortis has not previously been measured, although A. V. Hill (1912) measured the heat produced by frog’s muscles undergoing heat and chloroform rigor. The result suggested that the conversion of glycogen into lactic acid accounted for almost the whole of the heat produced. This has been found to be the case in the muscle of a normal well-fed rabbit when passing into rigor mortis , and also in the case of fatigued or exhausted muscle, but starved animals produce a larger quantity of heat than can be accounted for by the lactic acid produced.

scholarly journals CHANGES IN CARBON DIOXIDE TENSION AND HYDROGEN ION CONCENTRATION OF THE BLOOD FOLLOWING MULTIPLE PULMONARY EMBOLISM

1927 ◽  
Vol 45 (4) ◽  
pp. 633-641 ◽  
Author(s):  
Carl A. L. Binger ◽  
Richmond L. Moore
Keyword(s):  
Carbon Dioxide ◽  
Carbon Dioxide Tension ◽  
Hydrogen Ion ◽  
Ion Concentration ◽  
Hydrogen Ion Concentration ◽  
Characteristic Type ◽  
Pulmonary Capillaries ◽  
Partial Pressure Of Co2 ◽  
Shallow Breathing ◽  
Impaired Pulmonary Function

1. The production of multiple emboli of the pulmonary capillaries and arterioles results in rapid and shallow breathing which may be associated with anoxemia, but is not dependent for its occurrence upon anoxemia. 2. Similarly there may occur an increase in the partial pressure of CO2 in the blood as well as an increase in hydrogen ion concentration. 3. These changes must be regarded as the result of the impaired pulmonary function. 4. They are not, however, the cause of the rapid and shallow respirations, since the abnormal type of breathing may occur without the attendant blood changes. 5. The characteristic type of response to increase in CO2 tension is an increased rather than a decreased depth of respiration.

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