scholarly journals Metastatic potential of human melanoma cells in nude mice - characterisation of phenotype, cytokine secretion and tumour-associated antigens

1996 ◽  
Vol 74 (2) ◽  
pp. 194-199 ◽  
Author(s):  
D Schadendorf ◽  
I Fichtner ◽  
A Makki ◽  
S Alijagic ◽  
M Küpper ◽  
...  
Keyword(s):  
Nude Mice ◽  
Metastatic Potential ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Cytokine Secretion ◽  
Human Melanoma Cells ◽  
Tumour Associated Antigens

Sequential detection of mRNA for the chemokine IL-8 and macrophages (F4/80) in human melanoma

1995 ◽  
Vol 53 ◽  
pp. 1008-1009
Author(s):  
C.D. Bucana ◽  
R. Sanchez ◽  
R. Singh ◽  
I.J. Fidler
Keyword(s):  
Tumor Cells ◽  
Nude Mice ◽  
Constitutive Expression ◽  
Metastatic Potential ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Angiogenic Factor ◽  
Infiltrating Cells ◽  
Immunoperoxidase Assay ◽  
Multifunctional Cytokine

The purpose of this study was to demonstrate by ISH the presence of IL-8 mRNA, and by immunohistochemistry (IHC) the presence of the chemokine IL-8 and the distribution of infiltrating macrophages in subcutaneous melanomas in the same tumor. IL-8 is a multifunctional cytokine produced by melanoma cells, activated macrophages and monocytes and it has been shown to be a growth and angiogenic factor for tumor cells. More recently it was shown that constitutive expression of IL-8 correlated directly with metastatic potential of human melanoma cells in nude mice. IL-8 content of a solid tumor as determined by Western blot analysis does not take into account the contribution of macrophages. Previous studies showed that murine tumors contain many infiltrating cells interspersed among tumor cells whereas human tumors growing in nude mice exhibit macrophages at the periphery or between tumor islands. In this study we demonstrate the expression of IL-8 and the distribution of macrophages by immunoperoxidase assay and IL-8 mRNA by ISH.

Selective growth of human melanoma cells in the brain parenchyma of nude mice

1996 ◽  
Vol 6 (5) ◽  
pp. 363-371 ◽  
Author(s):  
T Fujimaki ◽  
J E Price ◽  
D Fan ◽  
C D Bucana ◽  
K Itoh ◽  
...  
Keyword(s):  
Nude Mice ◽  
Melanoma Cells ◽  
Brain Parenchyma ◽  
Human Melanoma ◽  
Selective Growth ◽  
Human Melanoma Cells ◽  
The Brain

Effect of Interferon-Gamma on the Expression of HLA-DR by Human Melanoma Cells of Varying Metastatic Potential

1990 ◽  
Vol 3 (3) ◽  
pp. 162-167 ◽  
Author(s):  
MARY J.C. HENDRIX ◽  
ELISABETH A. SEFTOR ◽  
MICHELLE D. ECKES ◽  
ADRIAN L. WINTERS ◽  
STANLEY P.L. LEONG ◽  
...  
Keyword(s):  
Interferon Gamma ◽  
Metastatic Potential ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Human Melanoma Cells ◽  
Hla Dr

scholarly journals The chemokine RANTES is secreted by human melanoma cells and is associated with enhanced tumour formation in nude mice

1999 ◽  
Vol 79 (7-8) ◽  
pp. 1025-1031 ◽  
Author(s):  
U Mrowietz ◽  
U Schwenk ◽  
S Maune ◽  
J Bartels ◽  
M Küpper ◽  
...  
Keyword(s):  
Nude Mice ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Human Melanoma Cells ◽  
Tumour Formation

Direct correlation between MUC18 expression and metastatic potential of human melanoma cells

1993 ◽  
Vol 3 (1) ◽  
pp. 35-42 ◽  
Author(s):  
M. Luca ◽  
B. Hunt ◽  
C. D. Bucana ◽  
J. P. Johnson ◽  
I. J. Fidler ◽  
...  
Keyword(s):  
Metastatic Potential ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Human Melanoma Cells

Abstract 4476: The effect of electrochemotherapy on metastatic potential of human melanoma cells SK-Mel28

2011 ◽  
Author(s):  
Maja Cemazar ◽  
Vesna Todorovic ◽  
Vid Mlakar ◽  
Damjan Glavac ◽  
Gregor Sersa
Keyword(s):  
Metastatic Potential ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Human Melanoma Cells

Distinct regulation of pHin and [Ca2+]in in human melanoma cells with different metastatic potential

1998 ◽  
Vol 176 (1) ◽  
pp. 196-205 ◽  
Author(s):  
Raul Martínez-Zaguilán ◽  
Gloria M. Martinez ◽  
Araceli Gomez ◽  
Mary J.C. Hendrix ◽  
Robert J. Gillies
Keyword(s):  
Metastatic Potential ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Human Melanoma Cells

Quantitative Evaluation of Anticancer Agents against Human Melanoma Cells Implanted in Nude Mice

Pathobiology ◽  
1986 ◽  
Vol 54 (3) ◽  
pp. 149-154 ◽  
Author(s):  
Arnold Lockshin ◽  
Beppino C. Giovanella ◽  
John S. Stehlin, Jr.
Keyword(s):  
Quantitative Evaluation ◽  
Nude Mice ◽  
Anticancer Agents ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Human Melanoma Cells
Sign in / Sign up

Export Citation Format

Share Document