scholarly journals mdm2 gene mediates the expression of mdr1 gene and P-glycoprotein in a human glioblastoma cell line

1996 ◽  
Vol 74 (8) ◽  
pp. 1263-1268 ◽  
Author(s):  
S Kondo ◽  
Y Kondo ◽  
H Hara ◽  
R Kaakaji ◽  
JW Peterson ◽  
...  
Keyword(s):  
Cell Line ◽  
Mdr1 Gene ◽  
Glioblastoma Cell Line ◽  
Glioblastoma Cell ◽  
Mdm2 Gene ◽  
Human Glioblastoma ◽  
Human Glioblastoma Cell Line ◽  
Human Glioblastoma Cell ◽  
P Glycoprotein

Establishment and Characterization of a Human Glioblastoma Cell Line Which Expresses Somatostatin and its Functional Receptor

1999 ◽  
Vol 11 (3) ◽  
pp. 215-222
Author(s):  
Nobuo HIROTA ◽  
Kiyoshi MATSUMOTO ◽  
Shigeki SUNAGA ◽  
Masataka IIDA ◽  
Hiroshi SAKAGAMI ◽  
...  
Keyword(s):  
Cell Line ◽  
Glioblastoma Cell Line ◽  
Glioblastoma Cell ◽  
Human Glioblastoma ◽  
Human Glioblastoma Cell Line ◽  
Human Glioblastoma Cell ◽  
Functional Receptor

scholarly journals Enhanced Anti-Tumor Activity in Mice with Temozolomide-Resistant Human Glioblastoma Cell Line-Derived Xenograft Using SN-38-Incorporated Polymeric Microparticle

2021 ◽  
Vol 22 (11) ◽  
pp. 5557
Author(s):  
Tao-Chieh Yang ◽  
Shih-Jung Liu ◽  
Wei-Lun Lo ◽  
Shu-Mei Chen ◽  
Ya-Ling Tang ◽  
...  
Keyword(s):  
Cell Line ◽  
Therapeutic Index ◽  
Glioblastoma Cell Line ◽  
Glioblastoma Cell ◽  
Human Glioblastoma ◽  
Human Glioblastoma Cell Line ◽  
Human Glioblastoma Cell ◽  
Therapeutic Benefits ◽  
Biodegradable Poly ◽  
Anti Tumor Activity

Glioblastoma multiforme (GBM) has remained one of the most lethal and challenging cancers to treat. Previous studies have shown encouraging results when irinotecan was used in combination with temozolomide (TMZ) for treating GBM. However, irinotecan has a narrow therapeutic index: a slight dose increase in irinotecan can induce toxicities that outweigh its therapeutic benefits. SN-38 is the active metabolite of irinotecan that accounts for both its anti-tumor efficacy and toxicity. In our previous paper, we showed that SN-38 embedded into 50:50 biodegradable poly[(d,l)-lactide-co-glycolide] (PLGA) microparticles (SMPs) provides an efficient delivery and sustained release of SN-38 from SMPs in the brain tissues of rats. These properties of SMPs give them potential for therapeutic application due to their high efficacy and low toxicity. In this study, we tested the anti-tumor activity of SMP-based interstitial chemotherapy combined with TMZ using TMZ-resistant human glioblastoma cell line-derived xenograft models. Our data suggest that treatment in which SMPs are combined with TMZ reduces tumor growth and extends survival in mice bearing xenograft tumors derived from both TMZ-resistant and TMZ-sensitive human glioblastoma cell lines. Our findings demonstrate that combining SMPs with TMZ may have potential as a promising strategy for the treatment of GBM.

Differently labeled peptide ligands for rapid investigation of receptor expression on a new human glioblastoma cell line

Peptides ◽  
2000 ◽  
Vol 21 (12) ◽  
pp. 1885-1893 ◽  
Author(s):  
Marlies Fabry ◽  
Chiara Cabrele ◽  
Hartwig Höcker ◽  
Annette G Beck-Sickinger
Keyword(s):  
Cell Line ◽  
Peptide Ligands ◽  
Receptor Expression ◽  
Glioblastoma Cell Line ◽  
Glioblastoma Cell ◽  
Human Glioblastoma ◽  
Human Glioblastoma Cell Line ◽  
Human Glioblastoma Cell

scholarly journals Genomic and transcriptomic characterization of the human glioblastoma cell line AHOL1

2021 ◽  
Vol 54 (3) ◽  
Author(s):  
W.A.S. Ferreira ◽  
C.K.N. Amorim ◽  
R.R. Burbano ◽  
R.A.R. Villacis ◽  
F.A. Marchi ◽  
...  
Keyword(s):  
Cell Line ◽  
Glioblastoma Cell Line ◽  
Glioblastoma Cell ◽  
Human Glioblastoma ◽  
Human Glioblastoma Cell Line ◽  
Human Glioblastoma Cell

scholarly journals The differential effects of neuroleptic drugs and PACAP on the expression of BDNF mRNA and protein in a human glioblastoma cell line

2017 ◽  
Vol 77 (3) ◽  
pp. 205-213 ◽  
Author(s):  
Marta Jóźwiak-Bębenista ◽  
Magdalena Jasińska-Stroschein ◽  
Edward Kowalczyk
Keyword(s):  
Cell Line ◽  
Glioblastoma Cell Line ◽  
Glioblastoma Cell ◽  
Neuroleptic Drugs ◽  
Bdnf Mrna ◽  
Human Glioblastoma ◽  
Human Glioblastoma Cell Line ◽  
Human Glioblastoma Cell ◽  
Differential Effects

Molecular cytogenetic analysis of a t(7; 10) in a human glioblastoma cell line

1995 ◽  
Vol 84 (2) ◽  
pp. 142
Author(s):  
Dan Fults ◽  
Carolyn A. Pedone ◽  
Xiao Lin Zhu ◽  
Briana J. Williams ◽  
Emma Jones ◽  
...  
Keyword(s):  
Cell Line ◽  
Cytogenetic Analysis ◽  
Glioblastoma Cell Line ◽  
Glioblastoma Cell ◽  
Human Glioblastoma ◽  
Human Glioblastoma Cell Line ◽  
Human Glioblastoma Cell ◽  
Molecular Cytogenetic

scholarly journals Recombinant adeno-associated virus (rAAV) expressing TFPI-2 inhibits invasion, angiogenesis and tumor growth in a human glioblastoma cell line

2005 ◽  
Vol 115 (6) ◽  
pp. 998-1005 ◽  
Author(s):  
Niranjan Yanamandra ◽  
Shakuntala Kondraganti ◽  
Christopher S. Gondi ◽  
Meena Gujrati ◽  
William C. Olivero ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Cell Line ◽  
Glioblastoma Cell Line ◽  
Glioblastoma Cell ◽  
Adeno Associated Virus ◽  
Human Glioblastoma ◽  
Human Glioblastoma Cell Line ◽  
Human Glioblastoma Cell

scholarly journals N-(2-hydroxyphenyl)acetamide (NA-2) and Temozolomide synergistically induce apoptosis in human glioblastoma cell line U87

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Farina Hanif ◽  
Kahkashan Perveen ◽  
Huma Jawed ◽  
Aqeel Ahmed ◽  
Saima M Malhi ◽  
...  
Keyword(s):  
Cell Line ◽  
Glioblastoma Cell Line ◽  
Glioblastoma Cell ◽  
Human Glioblastoma ◽  
Human Glioblastoma Cell Line ◽  
Human Glioblastoma Cell

scholarly journals Decrease in TTP pools mediated by 5-bromo-2'-deoxyuridine exposure in a human glioblastoma cell line

1992 ◽  
Vol 43 (7) ◽  
pp. 1579-1585 ◽  
Author(s):  
Donna S. Shewach ◽  
JoAnn Ellero ◽  
William R. Mancini ◽  
William D. Ensminger
Keyword(s):  
Cell Line ◽  
Glioblastoma Cell Line ◽  
Glioblastoma Cell ◽  
Human Glioblastoma ◽  
Human Glioblastoma Cell Line ◽  
Human Glioblastoma Cell
Sign in / Sign up

Export Citation Format

Share Document