Live-cell imaging RNAi screen identifies PP2A–B55α and importin-β1 as key mitotic exit regulators in human cells

Michael H. A. Schmitz; Michael Held; Veerle Janssens; James R. A. Hutchins; Otto Hudecz; Elitsa Ivanova; Jozef Goris; Laura Trinkle-Mulcahy; Angus I. Lamond; Ina Poser; Anthony A. Hyman; Karl Mechtler; Jan-Michael Peters; Daniel W. Gerlich

doi:10.1038/ncb2092

Live-cell imaging RNAi screen identifies PP2A–B55α and importin-β1 as key mitotic exit regulators in human cells

Nature Cell Biology ◽

10.1038/ncb2092 ◽

2010 ◽

Vol 12 (9) ◽

pp. 886-893 ◽

Cited By ~ 229

Author(s):

Michael H. A. Schmitz ◽

Michael Held ◽

Veerle Janssens ◽

James R. A. Hutchins ◽

Otto Hudecz ◽

...

Keyword(s):

Live Cell Imaging ◽

Cell Imaging ◽

Mitotic Exit ◽

Rnai Screen ◽

Human Cells ◽

Live Cell

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Live Cell Imaging of the Human Cells Depleted with Kinesin Family Member C1 (KIFC1) and Stathmin/Op18 shows that these Cells Process Mitosis with Lagging Chromosome and Micronuclei, Suggesting a Critical Role of KIFC1 and Stathmin/Op18 in Genomic Stability during Mitosis

Biophysical Journal ◽

10.1016/j.bpj.2011.11.3814 ◽

2012 ◽

Vol 102 (3) ◽

pp. 702a-703a

Author(s):

Kiwon Song

Keyword(s):

Family Member ◽

Live Cell Imaging ◽

Cell Imaging ◽

Critical Role ◽

Genomic Stability ◽

Human Cells ◽

Live Cell ◽

Lagging Chromosome ◽

Kinesin Family

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Faculty Opinions recommendation of Synthesis and application of fluorescence-labeled Ras-proteins for live-cell imaging.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1021921.249626 ◽

2004 ◽

Author(s):

Dennis Hall

Keyword(s):

Live Cell Imaging ◽

Cell Imaging ◽

Live Cell ◽

Ras Proteins

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Faculty Opinions recommendation of Live-cell imaging reveals replication of individual replicons in eukaryotic replication factories.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1033142.389091 ◽

2006 ◽

Author(s):

Andrew Belmont

Keyword(s):

Live Cell Imaging ◽

Cell Imaging ◽

Live Cell

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Faculty Opinions recommendation of Live-cell imaging of enzyme-substrate interaction reveals spatial regulation of PTP1B.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1060705.537867 ◽

2007 ◽

Author(s):

Karen Allen

Keyword(s):

Live Cell Imaging ◽

Cell Imaging ◽

Live Cell ◽

Spatial Regulation ◽

Substrate Interaction ◽

Enzyme Substrate

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Faculty Opinions recommendation of Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717952551.793492296 ◽

2014 ◽

Author(s):

Wade Clapp ◽

Grzegorz Nalepa

Keyword(s):

Dna Repair ◽

Live Cell Imaging ◽

Cell Imaging ◽

S Phase ◽

Live Cell ◽

Dna Repair Mechanisms ◽

Gradual Shift ◽

Repair Mechanisms

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Faculty Opinions recommendation of Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717952551.793458053 ◽

2012 ◽

Author(s):

Junjie Chen

Keyword(s):

Dna Repair ◽

Live Cell Imaging ◽

Cell Imaging ◽

S Phase ◽

Live Cell ◽

Dna Repair Mechanisms ◽

Gradual Shift ◽

Repair Mechanisms

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Faculty Opinions recommendation of Live cell imaging unveils multiple domain requirements for in vivo dimerization of the glucocorticoid receptor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718314288.793503485 ◽

2015 ◽

Author(s):

Stafford Lightman ◽

Becky Conway-Campbell

Keyword(s):

Glucocorticoid Receptor ◽

Live Cell Imaging ◽

Cell Imaging ◽

Live Cell ◽

Multiple Domain

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SCOPE-Seq: a scalable technology for linking live cell imaging and single-cell RNA sequencing

Genome Biology ◽

10.1186/s13059-018-1607-x ◽

2018 ◽

Vol 19 (1) ◽

Cited By ~ 15

Author(s):

Jinzhou Yuan ◽

Jenny Sheng ◽

Peter A. Sims

Keyword(s):

Single Cell ◽

Rna Sequencing ◽

Live Cell Imaging ◽

Cell Imaging ◽

Live Cell ◽

Single Cell Rna Sequencing

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Tracking Bacterial Chromosome Dynamics with Microfluidics-Based Live Cell Imaging

Methods in Molecular Biology - SMC Complexes ◽

10.1007/978-1-4939-9520-2_17 ◽

2019 ◽

pp. 223-238 ◽

Cited By ~ 2

Author(s):

Suchitha Raghunathan ◽

Anjana Badrinarayanan

Keyword(s):

Live Cell Imaging ◽

Cell Imaging ◽

Live Cell ◽

Bacterial Chromosome ◽

Chromosome Dynamics

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Simple Fluorescence Turn-On Chemosensor for Selective Detection of Ba2+ Ion and Its Live Cell Imaging

Analytical Chemistry ◽

10.1021/acs.analchem.9b02057 ◽

2019 ◽

Vol 91 (15) ◽

pp. 10095-10101 ◽

Cited By ~ 20

Author(s):

Palanisamy Ravichandiran ◽

Sivakumar Allur Subramaniyan ◽

Antony Paulraj Bella ◽

Princy Merlin Johnson ◽

Ae Rhan Kim ◽

...

Keyword(s):

Live Cell Imaging ◽

Cell Imaging ◽

Live Cell ◽

Selective Detection ◽

Turn On ◽

Fluorescence Turn On

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