Comparison of efficacy and health-related quality of life of first-line haploidentical hematopoietic stem cell transplantation with unrelated cord blood infusion and first-line immunosuppressive therapy for acquired severe aplastic anemia

Leukemia ◽  
2020 ◽  
Vol 34 (12) ◽  
pp. 3359-3369
Author(s):  
Limin Liu ◽  
Yanming Zhang ◽  
Wenjing Jiao ◽  
Huifen Zhou ◽  
Qingyuan Wang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Stem Cell ◽  
Health Related Quality ◽  
First Line ◽  
Hematopoietic Stem ◽  
Related Quality ◽  
Health Related ◽  
Unrelated Cord Blood ◽  
Acquired Severe Aplastic Anemia

scholarly journals Health-Related Quality of Life Following Allogeneic Hematopoietic Stem Cell Transplantation

Hematology ◽  
2010 ◽  
Vol 2010 (1) ◽  
pp. 248-254 ◽  
Author(s):  
Margaret Bevans
Keyword(s):  
Quality Of Life ◽  
Stem Cell ◽  
Clinical Practice ◽  
Hematopoietic Stem Cell Transplantation ◽  
Health Related Quality ◽  
Hematopoietic Stem ◽  
Allogeneic Hsct ◽  
Related Quality ◽  
Health Related

Abstract It is common knowledge that an allogeneic hematopoietic stem cell transplantation (HSCT) will have an enormous impact on the lives of transplant recipients and their families. Once an appropriate donor is identified, the curative potential of this treatment often drives the decision to proceed knowing that there will be intense physiologic toxicities and adverse effects on health-related quality of life (HRQL). Twenty-five years ago, HRQL was identified as an efficacy parameter in the evaluation of new anticancer drug therapy. Overall, the evidence suggests that an allogeneic HSCT has a significant impact on the overall HRQL of recipients, which is a result of decrements across all dimensions, including a significant symptom profile. The degree of impact on overall HRQL and the multiple dimensions varies across the transplant trajectory. Specific HRQL dimensions, such as physical function and symptoms, are easily incorporated into a clinician's assessment whereas other dimensions (eg, psychosocial) are less commonly integrated. The translation of HRQL results to improve clinical practice is not well established. Clinicians are often uncertain when to assess the scope of HRQL and how to interpret the information in a clinically meaningful way. The purpose of this review is to highlight the quality-of-life effects of allogeneic HSCT and discuss application into clinical practice.

scholarly journals Predonation Health-Related Quality of Life Scores Predict Time to Recovery in Hematopoietic Stem Cell Donors

2015 ◽  
Vol 21 (2) ◽  
pp. 350-356 ◽  
Author(s):  
Annelies Billen ◽  
J. Alejandro Madrigal ◽  
Andre Strydom ◽  
Richard M. Szydlo ◽  
Galen E. Switzer ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Stem Cell ◽  
Hematopoietic Stem Cell ◽  
Health Related Quality ◽  
Hematopoietic Stem ◽  
Related Quality ◽  
Health Related

Oral health-related quality of life before hematopoietic stem cell transplantation

2015 ◽  
Vol 19 (9) ◽  
pp. 2345-2349 ◽  
Author(s):  
J. E. Tinoco-Araujo ◽  
E. S. L. Orti-Raduan ◽  
D. Santos ◽  
V. A. R. Colturato ◽  
M. P. Souza ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Stem Cell ◽  
Oral Health ◽  
Hematopoietic Stem Cell Transplantation ◽  
Stem Cell Transplantation ◽  
Health Related Quality ◽  
Hematopoietic Stem ◽  
Related Quality ◽  
Health Related
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