Effects of renal denervation on blood pressures in patients with hypertension: a systematic review and meta-analysis of randomized sham-controlled trials

2021 ◽  
Author(s):  
Yukako Ogoyama ◽  
Kazuhiro Tada ◽  
Makiko Abe ◽  
Shinsuke Nanto ◽  
Hirotaka Shibata ◽  
...  
Keyword(s):  
Systematic Review ◽  
Renal Denervation ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Blood Pressures

scholarly journals EFFECT OF RENAL DENERVATION ON AMBULATORY BLOOD PRESSURE IN PATIENTS WITH UNCONTROLLED HYPERTENSION: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED, SHAM-CONTROLLED TRIALS

2021 ◽  
Vol 39 (Supplement 1) ◽  
pp. e290
Author(s):  
Konstantinos Stavropoulos ◽  
Dimitrios Patoulias ◽  
Alexandra Katsimardou ◽  
Konstantinos Imprialos ◽  
Konstantinos Koutsampasopoulos ◽  
...  
Keyword(s):  
Systematic Review ◽  
Blood Pressure ◽  
Ambulatory Blood Pressure ◽  
Renal Denervation ◽  
Meta Analysis ◽  
Uncontrolled Hypertension ◽  
Controlled Trials

scholarly journals EFFECT OF RENAL DENERVATION ON RENAL FUNCTION OF PATIENTS WITH UNCONTROLLED HYPERTENSION: INSIGHTS FROM A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED, SHAM-CONTROLLED TRIALS

2021 ◽  
Vol 39 (Supplement 1) ◽  
pp. e290-e291
Author(s):  
Konstantinos Stavropoulos ◽  
Alexandra Katsimardou ◽  
Dimitrios Patoulias ◽  
Konstantinos Imprialos ◽  
Sofia Bouloukou ◽  
...  
Keyword(s):  
Systematic Review ◽  
Renal Function ◽  
Renal Denervation ◽  
Meta Analysis ◽  
Uncontrolled Hypertension ◽  
Controlled Trials

The Effects of Quercetin Supplementation on Blood Pressures and Endothelial Function Among Patients with Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-analysis of Randomized Controlled Trials

2019 ◽  
Vol 25 (12) ◽  
pp. 1372-1384 ◽  
Author(s):  
Omid R. Tamtaji ◽  
Alireza Milajerdi ◽  
Ehsan Dadgostar ◽  
Fariba Kolahdooz ◽  
Maryam Chamani ◽  
...  
Keyword(s):  
Systematic Review ◽  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Endothelial Function ◽  
Randomized Controlled Trials ◽  
Adhesion Molecule ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Blood Pressures

Background: This systematic review and meta-analysis of randomized controlled trials (RCTs) were performed to determine the effect of quercetin administration on blood pressures and endothelial function among patients with metabolic syndrome (MetS) and related disorders. Methods: We searched systematically online databases including Cochrane Library, EMBASE, MEDLINE, and Web of Science to identify the relevant RCTs until December 2018. Q-test and I2 statistics were applied to assess heterogeneity among the included studies. Data were pooled using a random-effects model and weighted mean difference (WMD) was considered as the overall effect size. Results: Out of 284 citations, 8 RCTs were included in the meta-analysis. We found a significant reduction in systolic blood pressure (SBP) (WMD: -1.69; 95% CI: -3.22, -0.17) following the intake of quercetin supplements. However, quercetin supplementation did not significantly affect diastolic blood pressure (DBP) (WMD: -3.14; 95% CI: -8.24, 1.95), vascular cell adhesion molecule 1 (VCAM-1) (WMD: -24.49; 95% CI: -53.74, 4.77) and intercellular adhesion molecule 1 (ICAM-1) (WMD: -5.78; 95% CI: -12.93, 1.38). Conclusions: In summary, the current meta-analysis demonstrated that quercetin supplementation significantly reduced SBP, yet did not affect DBP, VCAM-1 and ICAM-1 among patients with MetS and related disorders.

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