scholarly journals Short foveo-disc distance in situs inversus of optic disc

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Young In Shin ◽  
Kyoung Min Lee ◽  
Martha Kim ◽  
Sohee Oh ◽  
Seok Hwan Kim
Keyword(s):  
Optic Nerve ◽  
Nerve Fiber ◽  
Layer Thickness ◽  
Optic Disc ◽  
Situs Inversus ◽  
Axial Length ◽  
Posterior Pole ◽  
Fiber Layer ◽  
Nerve Fiber Layer Thickness ◽  
The Mean

Abstract Situs inversus of optic disc (SIOD) is thought to be a congenital optic disc abnormality that is caused by dysversion of optic nerve insertion. SIOD, however, has many additional features that cannot be explained by abnormal optic-nerve-insertion directionality. In this study, we measured the distance between the fovea and disc in 22 eyes of 15 SIOD patients. For comparison, two control eyes were matched with each SIOD eye by age and axial length. The vertical distance between the temporal vascular arcades also was measured. The foveo-disc distance was shorter in the SIOD eyes than in the control eyes, while the inter-arcade distance did not differ. Further, we measured the circumpapillary retinal nerve fiber layer thickness, which showed nasal crowding of two humps in the SIOD eyes. This nasal crowding disappeared when we shifted the circle scan by the mean difference (465 μm) of the foveal-disc distance between the two groups. Our findings suggest that the optic disc was located closer to the fovea than it would have been normally. Thus, SIOD might reflect incomplete expansion of the posterior pole in the direction of the fovea-disc axis.

scholarly journals Comparing characteristics of the optic nerve head among subjects with suspected glaucoma in different ages of onset

2018 ◽  
Vol 146 (3-4) ◽  
pp. 136-142
Author(s):  
Vesna Maric ◽  
Vujica Markovic ◽  
Marija Bozic ◽  
Ivan Marjanovic
Keyword(s):  
Optic Nerve ◽  
Nerve Fiber ◽  
Layer Thickness ◽  
Optic Disc ◽  
Retinal Nerve Fiber Layer ◽  
Optic Nerve Head ◽  
Fiber Layer ◽  
Nerve Fiber Layer Thickness ◽  
Neuroretinal Rim ◽  
Disc Area

Introduction/Objective. Evaluation of the optic nerve head (ONH) is an inevitable procedure in the diagnosis of glaucoma. One of the most common imaging techniques for a quantitative assessment of the topography of the ONH is the Heidelberg retinal tomography II (HRT II). The aim of this study was to determine quantitative stereometric parameters of the ONH by using the HRT II and to investigate any damage of neuroretinal rim in children with suspected glaucoma and compared these data with the group of adults with suspected glaucoma. Methods. This comparative study included 167 (167 eyes) children aged 11?3 years with suspected juvenile glaucoma and 175 adult participants (175 eyes), aged 60?3 years, also with suspected glaucoma, examined between January 2013 and April 2014. Optic nerve head topography and retinal nerve fiber layer thickness measurements were assessed using a HRT II. Results. Data analysis in this study showed that the average mean values for children/adults were: disc area (mm2) 2.828?0.489/2.663?0.412 (p<0.001); rim area (mm2) 1.873?0.391/1.667?0.275 (p<0.001); cup/disc area ratio 0.369?0.125/0.369?0.101 (p=0.530); mean retinal nerve fiber layer thickness (mm) 0.223?0.078/0.219?0.055 (p=0.494). Statistically significant difference in damage of neuroretinal rim, between children and adults, was found in temporal (T) and temporal-inferior (Ti) segments. Conclusions. There were differences in some of the investigated quantitative parameters of the ONH between children and adults, as optic disc size, cup and rim area and rim volume. By using MRA, difference in the damage of the neuroretinal rim, when comparing children and adult optic discs appeared only in T and Ti segments, which means that optic disc cupping has spread more in children than in adults.

Comparative Analysis of Retinal Nerve Fiber Layer Thickness between Normal and Mild to Moderately Myopic Eyes

2021 ◽  
Vol 37 (4) ◽  
Author(s):  
Gul Nasreen ◽  
Shaheer Suhail Sarwar ◽  
Irfana Bibi ◽  
Muhammad Arslan Ashraf
Keyword(s):  
Optical Coherence Tomography ◽  
Nerve Fiber ◽  
Layer Thickness ◽  
Retinal Nerve Fiber Layer ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Nerve Fiber Layer Thickness ◽  
Rnfl Thickness ◽  
The Mean ◽  
Retinal Nerve Fiber

Purpose:  To determine the difference between mean retinal nerve fiber layer (RNFL) thickness in myopic eyes (up to -6.00D) and normal eyes. Study Design:  Descriptive observational study. Place and Duration of the Study:  Eye department of Mayo hospital Lahore, from February 2019 to April 2019. Methods:  We compared the mean RNFL between 58 myopic eyes (up to -6.00 D) and age matched 60 normal eyes. The age of the participants was between 12 to 42 years. Complete ocular examination was done and RNFL thickness was measured by using Optical coherence tomography (NIDEX RS-33.0, software-ex 1.5.2).Data was analyzed by independent sample t-test by using SPSS; with P < .05 as significant. Results:  The mean difference among these groups was 5.852 µm with (SE: 1.929). Mean RNFL thickness in myopic group was (95.93 ± 10.158µm) with (SE: 1.334). The result for mean RNFL thickness in myopic eyes was distributed normally as P < .03. Mean RNFL in normal group was (101.78 ± 10.774 µm) with (SE: 1.391), and the result of mean RNFL thickness measured in normal eyes was not distributed normally as P < .20. The results showed that there is a statistically significant difference between mean RNFL thickness measured in normal versus myopic eyes as (P < .003). Conclusion:  There is a significance difference between mean RNFL thickness between myopic eyes and normal eyes as measured by OCT. Careful interpretation of RNFL data in myopic eyes is recommended to avoid misdiagnosis with glaucoma. Key Words:  Retinal Nerve Fiber Layer thickness, Myopia, Optical Coherence Tomography.

Genetic Contributions to Glaucoma: Heritability of Intraocular Pressure, Retinal Nerve Fiber Layer Thickness, and Optic Disc Morphology

2007 ◽  
Vol 48 (8) ◽  
pp. 3669 ◽  
Author(s):  
Leonieke M. E. van Koolwijk ◽  
Dominiek D. G. Despriet ◽  
Cornelia M. van Duijn ◽  
Luba M. Pardo Cortes ◽  
Johannes R. Vingerling ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Nerve Fiber ◽  
Layer Thickness ◽  
Optic Disc ◽  
Retinal Nerve Fiber Layer ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Nerve Fiber Layer Thickness ◽  
Genetic Contributions ◽  
Retinal Nerve Fiber
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