scholarly journals Chronic kidney disease and pregnancy outcomes

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Dvořák Jan ◽  
Koucký Michal ◽  
Jančová Eva ◽  
Mysliveček Marek ◽  
Tesař Vladimír ◽  
...  

AbstractPregnancy complicated by CKD is currently not fully understood topic. Outcome of pregnancy in patients with CKD is related to impaired glomerular filtration rate and the degree of proteinuria. In our study we evaluated the association of serum creatinine level and proteinuria with both maternal and fetal outcomes in the cohort of 84 pregnant patients with CKD. In CKD group we confirmed negative correlation of highest serum creatinine level in pregnancy to fetal weight (p value < 0.001) and gestation period (p value < 0.001). Likewise, negative correlation of preconception serum creatinine to fetal weight (p value < 0.001) and gestation period (p value 0.002). Negative correlation of proteinuria to gestation period (p value < 0.001) and fetal weight (p value < 0.001) was also demonstrated. CKD is serious risk factor for pregnancy outcome. Proteinuria and serum creatinine level should be examined before pregnancy and regularly monitored during pregnancy. Higher serum creatinine levels and higher proteinuria predispose to shorter gestation period and lower birth weight of the neonate.

2015 ◽  
Vol 2 (2) ◽  
Author(s):  
Kambiz Novin ◽  
Shiva Moghadam ◽  
Nafiseh Mortazavi ◽  
Farnaz Hosseini Kamal ◽  
Helaleh Khoshbakht Ahmadi ◽  
...  

2020 ◽  
Vol 18 (3) ◽  
pp. 495-499
Author(s):  
Prashant Kumar Gupta ◽  
Laxman Kunwar ◽  
Bom BC ◽  
Aarti Gupta

Background: Ultrasonography is widely used to evaluate the kidney status. Serum creatinine and glomerular filtration rate assess the functional status of the kidney. This study tried to find the association between renal parameters in ultrasonography, serum creatinine and estimated glomerular filtration rate in patients with echogenic kidneys. Methods: Study was done in 61 patients. Four sonographic renal parameters (renal echogenicity grade, renal length, cortical thickness, parenchymal thickness) were obtained from patients showing echogenic kidneys irrespective of cause during ultrasonography of abdomen. Glomerular filtration rate was calculated using Modified Diet in Renal Disease formula after obtaining patient’s serum creatinine level. Sonographic renal parameters were compared with serum creatinine and estimated glomerular filtration rate using Pearson’s correlation coefficient and one-way ANOVA tests. Results: The study showed significant correlation of only renal echogenicity grade and parenchymal thickness with eGFR. However, all four sonographic renal parameters showed significant correlation with serum creatinine level. Renal echogenicity grading had strongest correlation with both serum creatinine (r=0.571, p=0.000) and estimated glomerular filtration rate (r= -0.349, p=0.006). Mean serum creatinine (in mg/dL) ± standard deviation was 1.9(±1.5), 4.0(±3.7), 5.8(±3.7), and 15.4(±5.3) for grade I, II, III, and IV echogenic kidneys respectively. Similarly, mean eGFR (in ml/min/1.73m2) ± standard deviation was 50.2(±22.9), 35.9(±40), 15.7(±13.4), and 3.4(±1.1) for Grade I, II, III, and IV echogenic kidneys respectively. Conclusions: Renal echogenicity is a better sonographic parameter that correlated well with both eGFR and serum creatinine. Renal ultrasound should be routinely used for early diagnosis, grading and monitoring of kidney disease. Keywords: Correlation; estimated glomerular filtration rate; renal echogenicity; serum creatinine; ultrasound


2019 ◽  
Vol 1 (1) ◽  
pp. 19-24
Author(s):  
Nala Fidarotul Ulya ◽  
Gilang Kusdinar ◽  
Kurniawan Santoso

Chronic kidney disease (CKD) is kidney damage that occurs for more than 3 months with a glomerular filtration rate of less than 60 ml/sec/ 1.73 m2. WHO estimates that in Indonesia, there will be an increase in PGK in 1995-2025 by 41.4%. Over the past 40 years, Creatinine serum has become the most common and cheap serum marker for kidney function. One of the most common complications in patients with PGK is anemia. Anemia in PGK can be caused by several factors such as EPO deficiency, iron deficiency, etc. One of the usual parameters checking is the iron status of TIBC. This study aims to determine the relationship of serum Creatinine level with TIBC in chronic kidney patients in Gambiran regional public hospital Kediri and sampling taken by quota sampling. The study used cross-sectional using Rank Spearman statistic test. This test is used for abnormally distributed data types. The measured variable was serum Creatinine level with TIBC. The results of this study indicate that the value of p = (0.000)> α = (0.05), so H1 rejected and H0 accepted, then there is no relationship between serum Creatinine levels with TIBC in patients with chronic kidney disease in Gambiran Hospital Kediri.


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